- Must visit
Museum of Prehistoric Thera
Major archaeological museum displaying frescoes, pottery, and finds from Akrotiri; essential for understanding ancient Santorini.
Cheapest price on Oct 22
$255
Average ticket price on Oct 22
$434
Fastest journey on Oct 22
4 h 25 m
Average journey duration on Oct 22
6 h 57 m
Flights on Oct 22
13
Distance
1761 km
The best way to find a cheap flight ticket from Prague to Santorini (Island) is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Santorini (Island) will cost around $434 if you buy it on the day, but the cheapest tickets can be found for only $255.
It's difficult to get from Prague to Santorini (Island) without transferring at least once.
A3867 · A3354
A3867 · A3352
A3867 · A3364
LX1489+
LX8336
LX1487+
LX8336
A3867 · A3364
LH1393+
4Y1220
LH1393+
LH4362
OS650 · OS205+
LH4362
OS650 · OS205+
4Y1220Flights from Prague to Santorini (Island) depart on average 11 times per day, taking around 4h 49m. Cheap flight tickets for this journey start at $132 (€110) if you book in advance.
The earliest flight runs at 05:10, the last at 22:45. The fastest flight covers the 1094 miles (1761 km) distance in 2h 40m. September is the cheapest month to fly.
Distance 1094 miles (1761 km) |
Average flight duration 4h 49m |
Cheapest ticket price $132 (€110) |
Flights per day 11 |
Fastest flight 2h 40m |
First flight 5:10 AM |
Last flight 10:45 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 77 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Prague to Santorini (Island).
The table below shows live departures for Prague to Santorini (Island) flights for today, Wednesday, October 21. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:00 PM Prague | 4h25 | 9:25 PM Santorini (Island) | 0 transfersDirect | |
| Thursday, October 22 | |||||
OS650 · OS205+ LH4362 | 7:30 AM Prague Vaclav Havel Airport | 8h25 | 4:55 PM Santorini (Thira) National Airport | 2 transfers | |
OS650 · OS205+ 4Y1220 | 7:30 AM Prague Vaclav Havel Airport | 8h25 | 4:55 PM Santorini (Thira) National Airport | 2 transfers | |
OS650 · OS207+ 4Y1220 | 7:30 AM Prague Vaclav Havel Airport | 8h25 | 4:55 PM Santorini (Thira) National Airport | 2 transfers | |
OS650 · OS207+ LH4362 | 7:30 AM Prague Vaclav Havel Airport | 8h25 | 4:55 PM Santorini (Thira) National Airport | 2 transfers | |
LH1393+ LH4362 | 9:10 AM Prague Vaclav Havel Airport | 6h45 | 4:55 PM Santorini (Thira) National Airport | 1 transfer | |
LH1393+ 4Y1220 | 9:10 AM Prague Vaclav Havel Airport | 6h45 | 4:55 PM Santorini (Thira) National Airport | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Santorini (Island) — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santorini (Island) trip today.
Major archaeological museum displaying frescoes, pottery, and finds from Akrotiri; essential for understanding ancient Santorini.
Collection of sculptures, inscriptions, and ceramics from Archaic to Roman times in central Fira.
Museum in Oia presenting nautical instruments, ship models, and maritime history tied to the island’s seafaring past.
Famous whitewashed village of narrow lanes, cave houses, and caldera views; one of Santorini’s signature walking areas.
Bustling island capital with caldera promenades, shops, museums, and dramatic cliffside scenery day and night.
Long scenic trail linking the main caldera villages, offering some of the island’s best walking and volcanic views.
Creamy yellow split pea purée made from Santorini fava. A signature island dish prized for its rich flavor from the volcanic soil.
White eggplant grown on Santorini, often fried or baked. It is sweeter and less bitter than common eggplant and is a local specialty.
Tomato fritters made with Santorini cherry tomatoes, herbs, and often onion. A classic meze that highlights the island's intensely flavored tomatoes.
Renowned fine dining in Imerovigli with creative Greek tasting menus, polished service, and dramatic caldera sunset views.
Popular traditional tavern in Megalochori known for local meze, grilled dishes, and a relaxed courtyard atmosphere.
Well-known casual spot in Oia for fresh gyros, souvlaki, and other Greek staples, ideal for a quick inexpensive meal.
Very touristy and pricier than many Greek islands, especially for hotels, cliffside dining, and summer transport. Budget options exist but peak season costs rise fast.
Service may be included, but rounding up or leaving 5-10% at restaurants is common for good service. Round up taxi fares; small change for cafes is appreciated.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Santorini (Island).
Find answers to the most common questions about traveling from Prague to Santorini (Island) by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santorini (Island), this guide helps you travel smarter and with confidence.

Most Prague to Santorini (Island) flights use the Prague Vaclav Havel Airport to airport pair. Use this guide to compare Prague and Santorini (Island) airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Prague Vaclav Havel Airport is 11 km from Prague city centre. Public transport options include:
Prague Vaclav Havel Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in Terminals 1 and 2.
Lost and found is available at the station.
Available at Prague Vaclav Havel Airport: Parking, Taxis, WC.
Accessibility facilities are available at Prague Vaclav Havel Airport: Ramps, assistance.
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