- Must visit
Museum of Prehistoric Thera
Key archaeological museum displaying finds from Akrotiri and ancient Thera, including frescoes, pottery, and daily-life objects from the Bronze Age.
Flights from Prague to Santorini (Island) depart on average 23 times per day, taking around 5h 45m. Cheap flight tickets for this journey start at $142 (€116) if you book in advance.
The earliest flight runs at 05:10, the last at 22:45. The fastest flight covers the 1094 miles (1761 km) distance in 4h 25m. November is the cheapest month to fly.
Distance 1094 miles (1761 km) |
Average flight duration 5h 45m |
Cheapest ticket price $142 (€116) |
Flights per day 23 |
Fastest flight 4h 25m |
First flight 5:10 AM |
Last flight 10:45 PM |
Cheapest Month Nov |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 70 days |
Cheapest price
$216
Average price
$428
Fastest journey
4 h 20 m
Average duration
5 h 30 m
Flights per day
20
Distance
1761 km
The best way to find a cheap flight ticket from Prague to Santorini (Island) is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Santorini (Island) will cost around $428 if you buy it on the day, but the cheapest tickets can be found for only $216.
It's difficult to get from Prague to Santorini (Island) without transferring at least once.
A3867 · A3348
A3867 · A3352
A3867 · A3354
A3867 · A3364
OS644 · OS841
LH1691 · LH2624
A3867 · A3364
GQ352 · GQ761
GQ354 · GQ761
LH1691+
OS186 · OS841Omio recommends booking the flight as it is the most popular option from Prague to Santorini (Island) among Omio's users. If you are prioritising price take the flight with prices starting from $142. For those with little time consider booking a flight which can get you there in 5h 45m. The ticket price range depends on the travel mode: a flight costs an average of $142, and a flight costs an average of $142.
Distance: 1094 miles (1761 km)
Most popular Flight | Driving |
|---|---|
$377 Average price Cheapest | $569 Average price (fuel + tolls) |
8h 45m Average total duration Fastest 5h 45m Onboard + 3h 0m Additional time* | 30h 10m Average total duration (door-to-door) |
![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
The table below shows live departures for Prague to Santorini (Island) flights for tomorrow, Saturday, June 6. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
BA859 · BA692 | 7:20 AM Prague Vaclav Havel Airport | 9h10 | 5:30 PM Santorini (Thira) National Airport | 1 transfer | |
BA859 · BA688 | 7:20 AM Prague Vaclav Havel Airport | 7h55 | 4:15 PM Santorini (Thira) National Airport | 1 transfer | |
OS650+ OS207+ LH4362 | 7:30 AM Prague Vaclav Havel Airport | 8h15 | 4:45 PM Santorini (Thira) National Airport | 2 transfers | |
OS650 · OS205+ 4Y1220 | 7:30 AM Prague Vaclav Havel Airport | 8h15 | 4:45 PM Santorini (Thira) National Airport | 2 transfers | |
OS650+ OS207+ 4Y1220 | 7:30 AM Prague Vaclav Havel Airport | 8h15 | 4:45 PM Santorini (Thira) National Airport | 2 transfers | |
OS650 · OS205+ LH4362 | 7:30 AM Prague Vaclav Havel Airport | 8h15 | 4:45 PM Santorini (Thira) National Airport | 2 transfers | |
LH1393+ 4Y1220 | 9:10 AM Prague Vaclav Havel Airport | 6h35 | 4:45 PM Santorini (Thira) National Airport | 1 transfer | |
LH1393+ LH4362 | 9:10 AM Prague Vaclav Havel Airport | 6h35 | 4:45 PM Santorini (Thira) National Airport | 1 transfer | |
LH1689 · LH2624 | 9:35 AM Prague Vaclav Havel Airport | 8h10 | 6:45 PM Santorini (Thira) National Airport | 1 transfer | |
GQ761 · GQ356 | 10:25 AM Prague Vaclav Havel Airport | 9h50 | 9:15 PM Santorini (Thira) National Airport | 1 transfer | |
GQ354 · GQ761 | 10:25 AM Prague Vaclav Havel Airport | 6h20 | 5:45 PM Santorini (Thira) National Airport | 1 transfer | |
GQ352 · GQ761 | 10:25 AM Prague Vaclav Havel Airport | 6h00 | 5:25 PM Santorini (Thira) National Airport | 1 transfer | |
OS644 · OS841 | 11:15 AM Prague Vaclav Havel Airport | 8h35 | 8:50 PM Santorini (Thira) National Airport | 1 transfer | |
SN2810+ OS841+ OS294 | 11:50 AM Prague Vaclav Havel Airport | 8h00 | 8:50 PM Santorini (Thira) National Airport | 2 transfers | |
LH1691 · LH2624 | 1:25 PM Prague Vaclav Havel Airport | 4h20 | 6:45 PM Santorini (Thira) National Airport | 1 transfer | |
LH1691+ OS186 · OS841 | 1:25 PM Prague Vaclav Havel Airport | 6h25 | 8:50 PM Santorini (Thira) National Airport | 2 transfers | |
A3867 · A3364 | 7:00 PM Prague Vaclav Havel Airport | 4h25 | 12:25 AM Santorini (Thira) National Airport | 1 transfer | |
A3867 · A3348 | 7:00 PM Prague Vaclav Havel Airport | 12h40 | 8:40 AM Santorini (Thira) National Airport | 1 transfer | |
A3867 · A3354 | 7:00 PM Prague Vaclav Havel Airport | 15h05 | 11:05 AM Santorini (Thira) National Airport | 1 transfer | |
A3867 · A3352 | 7:00 PM Prague Vaclav Havel Airport | 11h45 | 7:45 AM Santorini (Thira) National Airport | 1 transfer | |
Find all the dates and times for this journey
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Discover the best of Santorini — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santorini trip today.
Key archaeological museum displaying finds from Akrotiri and ancient Thera, including frescoes, pottery, and daily-life objects from the Bronze Age.
Small museum in Fira with sculpture, inscriptions, and ceramics from Archaic to Roman times, useful for understanding the island's long history.
Immersive museum-style attraction exploring the Atlantis legend through interactive exhibits and audiovisual displays tied to Santorini's volcanic history.
The island's most famous village for whitewashed lanes, cave houses, luxury viewpoints, and sunset scenes that dominate Santorini's global image.
Santorini's main town, combining caldera walks, shopping streets, nightlife, museums, and transport links, making it a practical and scenic base area.
Classic cliffside walking route linking major caldera settlements with sweeping volcano views, churches, and some of the island's best photo opportunities.
Silky yellow split-pea puree made from Santorini fava, usually served with olive oil, onion, and capers. It is one of the island's signature traditional dishes.
Santorini's famous tomato fritters made with the island's small, sweet tomatoes, herbs, and flour. A classic meze strongly associated with local home cooking.
The island's white eggplant is prized for its mild, less bitter flavor and is often baked, fried, or cooked in casseroles. It is a distinctive local agricultural product.
Widely known traditional taverna loved for Cretan and Santorini dishes, generous portions, and a warm local atmosphere away from the caldera crowds.
Historic fine-dining restaurant associated with modern Santorini cuisine, showcasing local ingredients and refined Greek flavors in an elegant setting.
Well-regarded seafood taverna near Vlychada known for fresh fish, straightforward Greek cooking, and a relaxed harborside feel.
Santorini is pricier than much of Greece, especially for hotels and caldera-view dining in peak season.
Service is often included, but a 5-10% tip is appreciated in restaurants for good service. Round up in taxis. Small change is fine in cafes and for hotel staff.
Official public transport app
Santorini (Thira) National Airport -> Fira Bus Station, Santorini
Find answers to the most common questions about traveling from Prague to Santorini (Island) by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santorini (Island), this guide helps you travel smarter and with confidence.

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