Journey information
Overview: Santa Cruz to Madrid flight
Flights from Santa Cruz to Madrid depart on average 10 times per day, taking around 13h 15m. Cheap flight tickets for this journey start at $501 (€399) if you book in advance.
There are 1 flights per day. The earliest flight runs at 07:40, the last at 17:30. The fastest flight covers the 5532 miles (8904 km) distance in 10h 40m. July is the cheapest month to fly.
Distance 5532 miles (8904 km) |
Average flight duration 13h 15m |
Cheapest ticket price $501 (€399) |
Flights per day 10 |
Direct flights 1 |
Fastest flight 10h 40m |
Cheapest month to travel July |
First flight 07:40 |
Last flight 17:30 |
The cheapest and fastest flights from Santa Cruz to Madrid
Cheapest price
$851
Average price
$851
Fastest journey
1 d 10 m
Average duration
1 d 10 m
Flights per day
1
Distance
8904 km
The best way to find a cheap flight ticket from Santa Cruz to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Cruz to Madrid will cost around $851 if you buy it on the day, but the cheapest tickets can be found for only $851.
Of the 1 flights that leave Santa Cruz for Madrid onFri, Feb 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 06 the direct flights cover the 8904 km distance in an average of 1 d 10 m but if you time it right, some flights will get you there in just 1 d 10 m .
On Fri, Feb 06 the longest flights will take 1 d 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Live departures
Santa Cruz to Madrid flight times
The table below shows live departures for Santa Cruz to Madrid flights for tomorrow, Friday, February 6. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:40 AM Santa Cruz | 24h10 | 7:50 AM Madrid | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Cruz to Madrid by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Feb 12
Why should you book Santa Cruz to Madrid flights with Omio?
Why book with Omio vs Air Europa?
- Compare with other providers: On Omio, you can not only buy tickets for Air Europa, but also compare tickets for the likes of Iberia, Avianca - Aerovias Nacionales de Colombia or LATAM Airlines to find the best option for your trip from Santa Cruz to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Edreams, Trip or Kayak?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Iberia, Avianca - Aerovias Nacionales de Colombia or LATAM Airlines to find the best option for your trip from Santa Cruz to Madrid.
Airlines: Air Europa, Avianca - Aerovias Nacionales de Colombia, Iberia, LATAM Airlines from Santa Cruz to MadridFind the best flights between Santa Cruz to Madrid with Omio's travel partners Air Europa, Avianca - Aerovias Nacionales de Colombia, Iberia, LATAM Airlines from $501 (€399). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Avianca - Aerovias Nacionales de Colombia
Air Europa
Iberia
LATAM Airlines
FAQs: Santa Cruz to Madrid Flight
Find answers to the most common questions about traveling from Santa Cruz to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- San Isidro Festival, a celebration honoring the patron saint of Madrid with parades and traditional music
- Madrid Pride, one of the largest LGBTQ+ pride events in Europe featuring a colorful parade
- La Paloma Festival, a local festival celebrating the Virgin of La Paloma with street parties and cultural activities
- Madrid Fashion Week, a showcase of the latest trends and designs from Spanish and international fashion designers.
- Epiphany, January, a traditional celebration with parades and the Three Kings' Day festivities
- Semana Santa, April, a significant religious observance with processions and cultural significance
- Assumption of Mary, August, a public holiday with various local celebrations and events
- National Day of Spain, October, commemorating the country's history with patriotic displays and activities.
More options for your journey from Santa Cruz to Madrid
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