Journey information
Overview: Santa Cruz to Madrid flight
Flights from Santa Cruz to Madrid depart on average 3 times per day, taking around 13h 8m. Cheap flight tickets for this journey start at $706 (€564) if you book in advance.
There are 1 flights per day. The earliest flight runs at 06:50, the last at 16:20. The fastest flight covers the 5532 miles (8904 km) distance in 10h 50m. December is the cheapest month to fly.
Distance 5532 miles (8904 km) |
Average flight duration 13h 8m |
Cheapest ticket price $706 (€564) |
Flights per day 3 |
Direct flights 1 |
Fastest flight 10h 50m |
Cheapest month to travel December |
First flight 06:50 |
Last flight 16:20 |
The cheapest and fastest flights from Santa Cruz to Madrid
Cheapest price
$1173
Average price
$2529
Fastest journey
10 h 40 m
Average duration
20 h 24 m
Flights per day
17
Distance
8904 km
The best way to find a cheap flight ticket from Santa Cruz to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Cruz to Madrid will cost around $2529 if you buy it on the day, but the cheapest tickets can be found for only $1173.
Of the 17 flights that leave Santa Cruz for Madrid onTue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct flights cover the 8904 km distance in an average of 20 h 24 m but if you time it right, some flights will get you there in just 10 h 40 m .
On Tue, Dec 23 the longest flights will take 1 d 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
UX26
AV166 · AV182
AV166 · AV18+
AV6001
AV166 · AV18+
AV6000
AV166 · AV18+
AV6153
UX26
AV166 · AV46
AV166 · AV182
AV166 · AV18+
AV6000
AV166 · AV18+
AV6001Live departures
Santa Cruz to Madrid flight times
The table below shows live departures for Santa Cruz to Madrid flights for tomorrow, Tuesday, December 23. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
AV166 · AV8553 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV18+ AV6001 | 7:40 AM Santa Cruz | 26h30 | 10:10 AM Madrid Barajas Airport | 2 transfers | |
AV166 · AV18+ AV6000 | 7:40 AM Santa Cruz | 26h00 | 9:40 AM Madrid Barajas Airport | 2 transfers | |
AV166 · AV9545 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV9543 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV9207 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV9209 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV18+ AV6153 | 7:40 AM Santa Cruz | 35h40 | 7:20 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV8523 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV9227 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV46 | 7:40 AM Santa Cruz | 14h40 | 10:20 PM Madrid Barajas Airport | 1 transfer | |
AV166 · AV9365 · AV14 | 7:40 AM Santa Cruz | 29h10 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV182 | 7:40 AM Santa Cruz | 24h10 | 7:50 AM Madrid Barajas Airport | 1 transfer | |
AV166 · AV18+ AV6017 | 7:40 AM Santa Cruz | 27h20 | 11:00 AM Madrid Barajas Airport | 2 transfers | |
AV166 · AV18+ AV6172 | 7:40 AM Santa Cruz | 30h15 | 1:55 PM Madrid Barajas Airport | 2 transfers | |
AV166 · AV18+ AV6019 | 7:40 AM Santa Cruz | 34h45 | 6:25 PM Madrid Barajas Airport | 2 transfers | |
UX26 | 5:30 PM Santa Cruz | 10h40 | 4:10 AM Madrid Barajas Airport | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Cruz to Madrid by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Airlines: Air Europa, Iberia, LATAM Airlines from Santa Cruz to MadridFind the best flights between Santa Cruz to Madrid with Omio's travel partners Air Europa, Iberia, LATAM Airlines from $706 (€564). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Air Europa
Iberia
LATAM Airlines
FAQs: Santa Cruz to Madrid Flight
Find answers to the most common questions about traveling from Santa Cruz to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- San Isidro Festival, a celebration honoring the patron saint of Madrid with parades and traditional music
- Madrid Pride, one of the largest LGBTQ+ pride events in Europe featuring a colorful parade
- La Paloma Festival, a local festival celebrating the Virgin of La Paloma with street parties and cultural activities
- Madrid Fashion Week, a showcase of the latest trends and designs from Spanish and international fashion designers.
- Epiphany, January, a traditional celebration with parades and the Three Kings' Day festivities
- Semana Santa, April, a significant religious observance with processions and cultural significance
- Assumption of Mary, August, a public holiday with various local celebrations and events
- National Day of Spain, October, commemorating the country's history with patriotic displays and activities.
Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you.
Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
More options for your journey from Santa Cruz to Madrid
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