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Journey information
Overview: Madrid to Santa Cruz flight
Spain
Bolivia
Flights from Madrid to Santa Cruz depart on average 8 times per day, taking around 14h 16m. Cheap flight tickets for this journey start at $455 (€370) if you book in advance.
There are 1 flights per day. The earliest flight runs at 02:05, the last at 23:45. The fastest flight covers the 5532 miles (8904 km) distance in 11h 20m. April is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 5532 miles (8904 km) |
Average flight duration 14h 16m |
Cheapest ticket price $455 (€370) |
Flights per day 8 |
Direct flights 1 |
Fastest flight 11h 20m |
First flight 02:05 |
Last flight 23:45 |
Cheapest month Apr |
Cheapest day Mon |
High season Oct - Dec |
Low season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
The cheapest and fastest flights from Madrid to Santa Cruz
Showing times and prices for Mar 24
Cheapest price
$617
Average price
$1235
Fastest journey
20 h 45 m
Average duration
22 h 33 m
Flights per day
3
Distance
8904 km
Cheap tickets
The best way to find a cheap flight ticket from Madrid to Santa Cruz is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Santa Cruz will cost around $1235 if you buy it on the day, but the cheapest tickets can be found for only $617.
Fast flights
Of the 3 flights that leave Madrid for Santa Cruz onTue, Mar 24, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct flights cover the 8904 km distance in an average of 22 h 33 m but if you time it right, some flights will get you there in just 20 h 45 m .
On Tue, Mar 24 the longest flights will take 1 d 1 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
09:50AM20h45
Madrid06:35AMSanta Cruz
$6171One-way
0 transfers
05:35AM25h00
Madrid06:35AMSanta Cruz
$14011One-way
0 transfers
09:55PM21h55
Madrid07:50PMSanta Cruz
$16881One-way
0 transfers
09:50AM20h45
Madrid06:35AMSanta Cruz
$6171One-way
0 transfers
09:55PM21h55
Madrid07:50PMSanta Cruz
$16881One-way
0 transfers
05:35AM25h00
Madrid06:35AMSanta Cruz
$14011One-way
0 transfers
Live departures
Madrid to Santa Cruz flight times
The table below shows live departures for Madrid to Santa Cruz flights for today, Monday, March 23. You can also manually refresh the results below to see updated flight journeys.
Last updated at 6:40 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| AV183 · AV167 | 9:50 AM Madrid Barajas Airport | 20h45 | 6:35 AM Santa Cruz | 1 transfer | |
| AV6146 · AV19 · AV167 | 12:00 PM Madrid Barajas Airport | 42h35 | 6:35 AM Santa Cruz | 2 transfers | |
LA8075 · LA632+ OB709 | 12:50 PM Madrid Barajas Airport | 31h50 | 8:40 PM Santa Cruz | 2 transfers | |
| AV6016 · AV19 · AV167 | 1:55 PM Madrid Barajas Airport | 40h40 | 6:35 AM Santa Cruz | 2 transfers | |
| AV6076 · AV19 · AV167 | 2:50 PM Madrid Barajas Airport | 39h45 | 6:35 AM Santa Cruz | 2 transfers | |
 IB765+LA8071+OB735 | 3:05 PM Madrid Barajas Airport | 28h45 | 7:50 PM Santa Cruz | 2 transfers | |
| IB723+LA8085+OB735 | 3:45 PM Madrid Barajas Airport | 28h05 | 7:50 PM Santa Cruz | 2 transfers | |
| AV6083 · AV19 · AV167 | 7:00 PM Madrid Barajas Airport | 35h35 | 6:35 AM Santa Cruz | 2 transfers | |
| LA8065 · LA753 · LA864 | 9:55 PM Madrid Barajas Airport | 36h45 | 10:40 AM Santa Cruz | 2 transfers | |
| LA8065 · LA763 · LA864 | 9:55 PM Madrid Barajas Airport | 36h45 | 10:40 AM Santa Cruz | 2 transfers | |
| LA8065 · LA8096 · LA864 | 9:55 PM Madrid Barajas Airport | 36h45 | 10:40 AM Santa Cruz | 2 transfers | |
| LA8065 · LA407 · LA864 | 9:55 PM Madrid Barajas Airport | 36h45 | 10:40 AM Santa Cruz | 2 transfers | |
LA8065+ LA1304+OB795 | 9:55 PM Madrid Barajas Airport | 21h45 | 7:40 PM Santa Cruz | 2 transfers | |
| LA8065+OB735 | 9:55 PM Madrid Barajas Airport | 21h55 | 7:50 PM Santa Cruz | 1 transfer | |
 UX25 | 10:35 PM Madrid Barajas Airport | 11h20 | 9:55 AM Santa Cruz | 0 transfersDirect | |
| LA1572+LA407 · LA864 | 10:55 PM Madrid Barajas Airport | 35h45 | 10:40 AM Santa Cruz | 2 transfers | |
| LA1572+LA753 · LA864 | 10:55 PM Madrid Barajas Airport | 35h45 | 10:40 AM Santa Cruz | 2 transfers | |
| Tuesday, March 24 | |||||
| 5:35 AM Madrid | 25h00 | 6:35 AM Santa Cruz | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Madrid to Santa Cruz by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Tue
Mar 24
Mar 24
Wed
Mar 25
Mar 25
Thu
Mar 26
Mar 26
Fri
Mar 27
Mar 27
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Mar 28
Mar 28
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Mar 30
Why should you book Madrid to Santa Cruz flights with Omio?
Air Europa as well as Avianca - Aerovias Nacionales de Colombia, LATAM Airlines, Iberia and more offer flights services from Madrid to Santa Cruz.
Omio is an official ticket reseller for all your travel options from Madrid to Santa Cruz.
Why book with Omio vs Air Europa?
- Compare with other providers: On Omio, you can not only buy tickets for Air Europa, but also compare tickets for the likes of Avianca - Aerovias Nacionales de Colombia, LATAM Airlines or Iberia to find the best option for your trip from Madrid to Santa Cruz.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Edreams, Trip or Kayak?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Avianca - Aerovias Nacionales de Colombia, LATAM Airlines or Iberia to find the best option for your trip from Madrid to Santa Cruz.
Airlines: Air Europa, Avianca - Aerovias Nacionales de Colombia, LATAM Airlines, Iberia from Madrid to Santa CruzFind the best flights between Madrid to Santa Cruz with Omio's travel partners Air Europa, Avianca - Aerovias Nacionales de Colombia, LATAM Airlines, Iberia from $455 (€370). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Avianca - Aerovias Nacionales de Colombia
About
Avianca is the national and largest airline of Colombia, and one of the oldest airlines in the world, tracing its origins back to 1919. It serves as the flagship of a group of airlines across the Americas, operating under a codesharing system. Avianca boasts an extensive network of destinations throughout the Americas, with its main hub located at El Dorado International Airport in Bogotá. The airline is a member of the Star Alliance, offering various classes of service from economy to business and first-class. Its fleet includes modern aircraft such as the Airbus A320 family, Airbus A330, and Boeing 787 Dreamliner.
Luggage & cancellation policy
Average Duration
20h 45m
Cheapest Price
$455 (€370)
Luggage included
1 carry-on bag (10kg) and 1 personal item included in most fares
Additional luggage
Additional checked baggage can be purchased, up to 32kg per piece
Cancellation Policy
Refunds available depending on fare type, some tickets non-refundable. Changes permitted with fee.
Pregnant on board
Pregnant women can travel up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel as unaccompanied minors with additional service fee. Must be booked at least 48 hours in advance
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested 48h before flight
Pets
Small pets in cabin, max 8kg including carrier
Entertaiment on board
Air Europa
About
Air Europa is Spain’s third most popular airline, offering flights across Europe and to destinations worldwide. For your next trip, you can choose between Economy and Business Class fares.
Luggage & cancellation policy
Average Duration
11h 20m
Cheapest Price
$552 (€449)
Luggage included
1 cabin bag (55x35x25 cm) max 10kg
Additional luggage
23kg checked baggage available for purchase
Cancellation Policy
Refunds available depending on fare type, Basic fares non-refundable, Flex fares refundable with fee
Pregnant on board
Pregnant women can fly up to 36 weeks (single pregnancy) or 32 weeks (multiple pregnancy). Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-11 can travel unaccompanied with UM service. Service must be booked in advance and fees apply
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Wheelchair assistance available, must be requested 48h before flight
Pets
Small pets under 8kg allowed in cabin, larger animals in hold
Entertaiment on board
LATAM Airlines
About
LATAM Airlines Peru, a subsidiary of LATAM Airlines Group, is a major airline based in Lima, Peru, and the dominant carrier in the Peruvian domestic market. It operates scheduled domestic and international flights, with its main hub at Jorge Chávez International Airport. The airline was formerly known as LAN Perú S.A. until 2015, when it was dissolved and rebranded as LATAM Airlines as part of the merger between LAN Airlines and TAM Airlines. LATAM Airlines Group, the parent company, is the largest airline group in South America.
Luggage & cancellation policy
Average Duration
20h 25m
Cheapest Price
$521 (€424)
Luggage included
1 carry-on bag (max 10kg) and 1 personal item
Additional luggage
Additional checked baggage can be purchased, up to 23kg per piece
Cancellation Policy
Free cancellation within 24 hours of booking, after that fees apply based on fare type and timing
Pregnant on board
Up to 32 weeks for single pregnancy, 28 weeks for multiple. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel alone with LATAM's Unaccompanied Minor service. Service must be requested at least 48 hours before flight
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, including wheelchairs and special assistance
Pets
Small pets allowed in cabin, max 8kg including carrier. Must be booked in advance
Entertaiment on board
Iberia
About
Iberia is the national airline of Spain and a key member of the International Airlines Group (IAG), operating flights throughout Europe and to major global destinations. Its wide range of services makes travel easy and flexible—Economy passengers enjoy affordable fares with comfort, while Business Class travelers can experience premium seating, exclusive lounges, and enhanced dining. From short domestic flights to intercontinental journeys, Iberia combines Spanish hospitality with modern amenities, making it a popular choice worldwide.
Luggage & cancellation policy
Average Duration
20h 25m
Cheapest Price
$554 (€451)
Luggage included
1 cabin bag (40x30x20 cm) and 1 checked bag (158 cm total dimensions) included in most fares except Basic
Additional luggage
Additional bags can be purchased, with prices varying by route and fare type
Cancellation Policy
Basic fares non-refundable, Flexible fares refundable with fee, Business fully refundable
Pregnant on board
Pregnant women can fly up to 36 weeks (single pregnancy) or 32 weeks (multiple pregnancy). Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-11 can travel alone using Iberia's unaccompanied minor service. Service is optional for ages 12-17
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Iberia provides assistance for passengers with reduced mobility, including wheelchair assistance and special services for visually or hearing impaired passengers
Pets
Small pets under 8kg in cabin, larger animals in hold. Must be booked in advance
Entertaiment on board
FAQs: Madrid to Santa Cruz Flight
Find answers to the most common questions about traveling from Madrid to Santa Cruz by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santa Cruz, this guide helps you travel smarter and with confidence.
Cheap plane tickets from Madrid to Santa Cruz can start from as little as $455 (€370) when you book in advance. The average flight ticket price for Madrid to Santa Cruz is $989 (€804) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Madrid to Santa Cruz is 11h 20m to travel the 5532 miles (8904 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Madrid to Santa Cruz leaves at 2:05 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Madrid to Santa Cruz leaves at 11:45 PM.
Yes, there are 1 direct flights a day from Madrid to Santa Cruz with . Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Madrid to Santa Cruz, you can count on Air Europa, Avianca - Aerovias Nacionales de Colombia, LATAM Airlines, Iberia for the best way to get you to Santa Cruz. You can also check all possible airlines who offer a service between Madrid and Santa Cruz and compare the amenities they offer before buying a plane ticket.
The cheapest month for a flight from Madrid to Santa Cruz is April.
Yes, you can take a flight between Madrid and Santa Cruz.
Santa Cruz is outside the Schengen Area. Travelers departing from Madrid will need a valid passport and may require a visa depending on their nationality. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 5 h in winter and 6 h in summer between Madrid and Santa Cruz.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
More options for your journey from Madrid to Santa Cruz
Here are some other resources that might have the information you need
Most popular flights to and from Santa Cruz and Madrid
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