- Must visit
Columbia Museum of Art
Major art museum with American, European, and Asian works plus rotating exhibitions in a central downtown setting.
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Travel Information
Compare train and flight for Tampa, FL to Columbia, SC
Omio recommends booking the train as it is the most popular option from Tampa, FL to Columbia, SC among Omio's users. If you are prioritising price, take the train, with an average ticket price of lei502 For those with little time, consider booking a flight, which has an average total journey time of 5h 35m. Average ticket prices depend on the travel mode: a train costs an average of lei502, while a flight costs an average of lei2648.
Distance: 426 miles (687 km)
Compare train with
Most popular Train | Flight | Driving |
|---|---|---|
lei502 Average price Cheapest | lei2648 Average price | lei103 Average price (fuel + tolls) |
12h 12m Average total duration 11h 42m Onboard + 30m Additional time* | 5h 35m Average total duration Fastest 3h 35m Onboard + 2h 0m Additional time* | 7h 23m Average total duration (door-to-door) |
 Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Tampa, FL to Columbia, SC is a train with an average price of lei502.
This is compared to other travel options from Tampa, FL to Columbia, SC:
A train is lei2146 less than a flight for this route with tickets for a flight from Tampa, FL to Columbia, SC costing on average lei2648.
The fastest way to travel from Tampa, FL to Columbia, SC is by flight with an average journey time of 3h 35m.
Other travel options to Columbia, SC take longer:
Train takes on average 11h 42m.
It's helpful to compare your options as there are 2 ways to travel between Tampa, FL and Columbia, SC including taking a train and flight.
We recommend using the train as it is the most popular way to get from Tampa, FL to Columbia, SC among Omio's users.
Tampa, FL to Columbia, SC Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:15PM | Arrival Time 06:45PM | Duration 21h30 | Departure days Thu | Cheapest price lei503 |
Compare prices and tickets Tampa, FL to Columbia, SC by train or flight
Compare train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Tampa, FL to Columbia, SC
USAUSA
Take a bus from Tampa, FL to Columbia, SC and enjoy the approximately 426 miles (687 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 08:45, the last at 15:00.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from lei241
Distance 426 miles (687 km) |
First bus 8:45 AM |
Last bus 3:00 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 77 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from lei241
Complete guide to Columbia, SC
Things to do in Columbia, SC
Discover the best of Columbia, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbia, SC trip today.
- Must visit
South Carolina State Museum
State museum covering art, history, science, and technology with immersive galleries and family-friendly exhibits.
- Recommended
South Carolina Confederate Relic Room and Military Museum
Military history museum with artifacts, uniforms, and exhibits on South Carolina service members across multiple conflicts.
- Must visit
Riverfront Park
Popular riverside green space with trails, historic canal views, and shaded walks near downtown and the river confluence.
- Recommended
The Vista
Revived warehouse district with galleries, public art, shops, and event spaces that showcase Columbia's creative scene.
- Recommended
Five Points
Lively university district with boutiques, murals, nightlife, and walkable blocks popular with locals and students.
FAQs: Bus from Tampa, FL to Columbia, SC
Find answers to the most common questions about traveling from Tampa, FL to Columbia, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbia, SC, this guide helps you travel smarter and with confidence.
Most popular bus connections from Tampa, FL
More options for your journey from Tampa, FL to Columbia, SC
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Most popular buses to and from Columbia, SC and Tampa, FL
Most popular bus connections to Columbia, SC
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