Tampa, FL to Lake City, FL bus with Greyhound

Mon, Sep 14
+ Add return
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Tampa, FL to Lake City, FL

Showing times, prices and bookable tickets for Sep 14

Cheapest price on Sep 14

$65

Average ticket price on Sep 14

$65

Fastest journey on Sep 14

10 h 25 m

Average journey duration on Sep 14

10 h 30 m

Buses on Sep 14

3

Distance

250 km

Cheap tickets

The best way to find a cheap bus ticket from Tampa, FL to Lake City, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Tampa, FL to Lake City, FL will cost around $65 if you buy it on the day, but the cheapest tickets can be found for only $65.

Fast buses

It's difficult to get from Tampa, FL to Lake City, FL without transferring at least once.

  • Greyhound · ·
    6:50 AM10h30
    Tampa, Marion Transit Center
    5:20 PMLake City, S Marion Ave (Lake City Greyhound Station), FL
    $651One-way
    2 transfers
  • FlixBusFlixBus+Greyhound
    10:25 PM10h35
    Tampa, USF Holly Drive (Central Plant), FL
    9:00 AMLake City, S Marion Ave (Lake City Greyhound Station), FL
    $651One-way
    1 transfer
  • FlixBusFlixBus+Greyhound
    10:35 PM10h25
    Tampa, Marion Transit Center
    9:00 AMLake City, S Marion Ave (Lake City Greyhound Station), FL
    $651One-way
    1 transfer

Travel Information

Compare bus for Tampa, FL to Lake City, FL

Omio recommends booking the bus as it is the most popular option from Tampa, FL to Lake City, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $62 For those with little time, consider booking a bus, which has an average total journey time of 6h 40m. Average ticket prices depend on the travel mode: a bus costs an average of $62, while a bus costs an average of $62.

Distance: 155 miles (250 km)

Compare bus with

Most popular
Bus
Driving

$62

Average price

Cheapest

$36

Average price

(fuel + tolls)

6h 40m

Average total duration

Fastest

6h 10m

Onboard

+

30m

Additional time*

2h 36m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

The cheapest way to travel from Tampa, FL to Lake City, FL is a bus with an average price of $62 (€50).

This is compared to other travel options from Tampa, FL to Lake City, FL:

A bus is $761 (€615) less than a flight for this route with tickets for a flight from Tampa, FL to Lake City, FL costing on average $823 (€665).

The fastest way to travel from Tampa, FL to Lake City, FL is by flight with an average journey time of 3h 42m.

Other travel options to Lake City, FL take longer:

Bus takes on average 6h 10m.

Yes, you can take a bus between Tampa, FL and Lake City, FL.
We recommend using the bus as it is the most popular way to get from Tampa, FL to Lake City, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $62 (€50) compared to roughly $36 (€29) in fuel and tolls — a saving of about $-25.29 (€-20.45). The journey takes 6h 10m versus 2h 36m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Tampa, FL to Lake City, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
02:10AM
Arrival Time
01:00PM
Duration
10h50
Departure days
Mon, Thu, Sat
Cheapest price
$76
Operator
Greyhound
Departure Time
02:50AM
Arrival Time
02:00PM
Duration
11h10
Departure days
Fri
Cheapest price
$54
Operator
Greyhound
Departure Time
06:50AM
Arrival Time
05:20PM
Duration
10h30
Departure days
Mon, Tue
Cheapest price
$62
Operator
Greyhound
Departure Time
10:50AM
Arrival Time
09:25PM
Duration
10h35
Departure days
Thu, Sat
Cheapest price
$89
Operator
Greyhound
Departure Time
11:50AM
Arrival Time
10:25PM
Duration
10h35
Departure days
Thu, Sun
Cheapest price
$49
Operator
Greyhound
Departure Time
10:25PM
Arrival Time
09:00AM
Duration
10h35
Departure days
Mon
Cheapest price
$65
Operator
Greyhound
Departure Time
10:35PM
Arrival Time
09:00AM
Duration
10h25
Departure days
Mon, Tue
Cheapest price
$52

Live departures

Tampa, FL to Lake City, FL bus times

The table below shows live departures for Tampa, FL to Lake City, FL buses for tomorrow, Monday, September 14. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · · 6:50 AM Tampa, Marion Transit Center
10h30
5:20 PM Lake City, S Marion Ave (Lake City Greyhound Station), FL2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Tampa, FL to Lake City, FL by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Sep 14
Tue
Sep 15
Wed
Sep 16
Thu
Sep 17
Fri
Sep 18
Sat
Sep 19
Sun
Sep 20

Why should you book Tampa, FL to Lake City, FL buses with Omio?

Greyhound as well as FlixBus offer buses services from Tampa, FL to Lake City, FL.
Omio is an official ticket reseller for all your travel options from Tampa, FL to Lake City, FL.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Tampa, FL to Lake City, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Tampa, FL to Lake City, FL.

Journey information

Overview: Bus from Tampa, FL to Lake City, FL

USAUSA
USAUSA
Icon of bus

Buses from Tampa, FL to Lake City, FL run on average 4 times per day, taking around 6h 10m. Cheap bus tickets for this journey start at $50 (€40) if you book in advance.

The earliest bus runs at 06:20, the last at 22:35. The fastest bus covers the 155 miles (250 km) distance in 5h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
155 miles (250 km)
Average bus duration
6h 10m
Cheapest ticket price
$50 (€40)
Buses per day
4
Fastest bus
5h 15m
First bus
6:20 AM
Last bus
10:35 PM
Cheapest Month
Aug
Cheapest Day
Thu
High Season
Oct - Dec
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Tampa, FL to Lake City, FLYou can travel by bus between Tampa, FL to Lake City, FL with Greyhound, FlixBus for as low as $50 (€40). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
5h 20m
Cheapest FlixBus Price
$68 (€55)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
5h 15m
Cheapest Greyhound Price
$50 (€40)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Tampa, FL to Lake City, FL

Find answers to the most common questions about traveling from Tampa, FL to Lake City, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lake City, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Tampa, FL to Lake City, FL can start from as little as $50 (€40) when you book in advance. The average bus ticket price for Tampa, FL to Lake City, FL is $62 (€50) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tampa, FL to Lake City, FL is 5h 15m to travel the 155 miles (250 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tampa, FL to Lake City, FL leaves at 6:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tampa, FL to Lake City, FL leaves at 10:35 PM.
There are 4 buses a day from Tampa, FL to Lake City, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Tampa, FL to Lake City, FL, you can count on Greyhound, FlixBus for the best way to get you to Lake City, FL. You can also check all possible bus companies who offer a service between Tampa, FL and Lake City, FL and compare the amenities they offer before buying a bus ticket.
When departing from Tampa, FL , you have various bus station options to start your journey from including Tampa, Marion Transit Center, Tampa, USF Holly Drive (Central Plant), FL, Saint Petersburg, Central Avenue N / Dr Martin Luther King St Jr, FL . When arriving in Lake City, FL , you can end your journey in bus stations like Lake City, S Marion Ave (Lake City Greyhound Station), FL .Passengers board the bus most frequently from Tampa, Marion Transit Center, which is located around away from the city centre, and they get off the bus at Lake City, S Marion Ave (Lake City Greyhound Station), FL, located 0 away from the city centre.
A trip to Lake City, FL from Tampa, FL is worth doing but not as a day trip with a journey time of 5h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tampa, FL to Lake City, FL is August.
Yes, you can take a bus between Tampa, FL and Lake City, FL.
Yes, the following accessibility options are available when taking the bus from Tampa, FL to Lake City, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Tampa, FL to Lake City, FL for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Tampa, FL to Lake City, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Tampa, FL to Lake City, FL.
Yes, the following luggage options are included when booking a bus ticket from Tampa, FL to Lake City, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Tampa, FL to Lake City, FL:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Tampa, FL to Lake City, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Tampa, FL to Lake City, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Tampa, FL to Lake City, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Tampa, FL to Lake City, FL with the following bus company: Greyhound, FlixBus.
Since neither Tampa, FL nor Lake City, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Tampa, FL to Lake City, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Lake City, FL, travelers should be cautious of petty theft and vehicle break-ins, especially in parking areas near popular attractions. It's advisable to avoid poorly lit or isolated areas at night. Common scams include overpriced services or unofficial tour operators; always use licensed providers for transportation and activities. Staying alert and securing personal belongings can help ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Tampa, FL to Lake City, FL

Most Tampa, FL to Lake City, FL buses use the Tampa, Marion Transit Center to Lake City, S Marion Ave (Lake City Greyhound Station) station pair. Use this guide to compare Tampa, FL and Lake City, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Tampa
Arrival bus stations in Lake City

Which Tampa, FL station do buses to Lake City, FL leave from?

Buses from Tampa, FL to Lake City, FL leave from Tampa, Marion Transit Center. The station is 0 miles (1 km) from Tampa, FL city centre at Marion Transit Center, 1211 N Marion St, Tampa, FL 33602, USA.
Tampa, Marion Transit CenterMarion Transit Center, 1211 N Marion St, Tampa, FL 33602, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Tampa, Marion Transit Center from Tampa city centre

Bus1, 5, 19, 30 · 3m · $5 · every ~15 min

Tampa, Marion Transit Center bus station facilities and services

Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.

Tickets and information

Ticket office support is available at Tampa, Marion Transit Center.

Parking, taxis and toilets

Available at Tampa, Marion Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.

Tampa, USF Holly Drive (Central Plant)University of South Florida, Central Plant, 13302 USF Chestnut Dr, Tampa, FL 33620, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre

Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:

BusFlixBus 2421 · 26m · $1
9, 400 · 1h 3m · $5 · every ~7 min
6 · 1h 9m · $5 · every ~5 min

Tampa, USF Holly Drive (Central Plant) bus station facilities and services

Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).

Tickets and information

Ticket office support is available at Tampa, USF Holly Drive (Central Plant).

Parking, taxis and toilets

Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.

More options for your journey from Tampa, FL to Lake City, FL

Here are some other resources that might have the information you need

Return journeys for buses from Lake City, FL to Tampa, FL
Tickets and more information for coaches to Tampa, FL
HomeBusesBuses in USATampa, FL to Lake City, FL bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone