- Must visit
COSI
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
The best way to find a cheap bus ticket from Syracuse, NY to Columbus, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Columbus, OH will cost around €154 if you buy it on the day, but the cheapest tickets can be found for only €154.
On Thu, Nov 05, we found 1 buses from Syracuse, NY to Columbus, OH, including 1 direct services.
On Thu, Nov 05 the direct buses cover the 666 km distance in an average of 17 h 25 m but if you time it right, some buses will get you there in just 17 h 25 m .
On Thu, Nov 05 the slowest buses will take 17 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Syracuse, NY to Columbus, OH run on average 3 times per day, taking around 12h 44m. Cheap bus tickets for this journey start at €62 if you book in advance.
The earliest bus runs at 00:20, the last at 21:10. The fastest bus covers the 413 miles (666 km) distance in 9h 15m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Syracuse, NY to Columbus, OH.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:00AM | Arrival Time 06:25PM | Duration 17h25 | Departure days Thu | Cheapest price €154 |
Operator FlixBus | Departure Time 01:00AM | Arrival Time 03:20AM | Duration 26h20 | Departure days Wed | Cheapest price €99 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 04:20AM | Duration 26h20 | Departure days Tue | Cheapest price €120 |
Operator Greyhound | Departure Time 04:30AM | Arrival Time 11:20PM | Duration 18h50 | Departure days Sun | Cheapest price €75 |
Operator FlixBus | Departure Time 07:00AM | Arrival Time 07:30PM | Duration 12h30 | Departure days Thu, Fri, Sat | Cheapest price €77 |
Operator Greyhound | Departure Time 08:30AM | Arrival Time 03:20AM | Duration 18h50 | Departure days Mon | Cheapest price €68 |
Operator Greyhound | Departure Time 01:25PM | Arrival Time 08:30AM | Duration 19h05 | Departure days Tue | Cheapest price €146 |
Operator Greyhound | Departure Time 06:15PM | Arrival Time 10:40AM | Duration 16h25 | Departure days Sun | Cheapest price €75 |
Operator Greyhound | Departure Time 07:35PM | Arrival Time 05:15AM | Duration 9h40 | Departure days Thu, Fri, Sat, Sun | Cheapest price €74 |
Operator Greyhound | Departure Time 09:00PM | Arrival Time 02:15PM | Duration 17h15 | Departure days Fri, Sat | Cheapest price €101 |
Operator Greyhound | Departure Time 11:35PM | Arrival Time 09:25AM | Duration 9h50 | Departure days Mon, Tue | Cheapest price €130 |
The table below shows live departures for Syracuse, NY to Columbus, OH buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:00 AM Syracuse, NY | 26h20 | 3:20 AM Columbus, OH | 0 transfersDirect | |
![]() | 1:25 PM Syracuse, NY | 19h05 | 8:30 AM Columbus, OH | 0 transfersDirect | |
![]() | 11:35 PM Syracuse, NY | 9h50 | 9:25 AM Columbus, OH | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Syracuse, NY to Columbus, OH with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Columbus, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Columbus, OH trip today.
A major science museum with hands-on exhibits, a planetarium, and family-friendly programs that make science engaging for all ages.
This leading art museum offers strong American and European collections, special exhibitions, and a notable sculpture garden.
Located on Ohio State's campus, this museum presents contemporary art and rotating exhibitions in an acclaimed modern building.
Columbus's best-known historic district has brick streets, restored homes, and a walkable atmosphere ideal for architecture lovers.
A scenic downtown riverfront park with fountains, trails, and skyline views, popular for walks, events, and photos.
This large botanical park is famous for seasonal displays, glasshouses, and the iconic Chihuly installation in the conservatory.
A tangy, tomato-based slaw served on hot dogs or sandwiches. It is a long-running Columbus comfort food linked to old local chili and diner culture.
A sweet, cinnamon-forward fried pastry sold at the Ohio State Fair since the early 1900s. It is one of central Ohio's most iconic fair treats.
A shredded chicken and cracker casserole common at Columbus-area potlucks and game days. It is a nostalgic Midwestern comfort dish in central Ohio.
Refined tasting-menu restaurant in the Short North with inventive seasonal cooking and one of the city's strongest fine dining reputations.
Acclaimed local brewery and gastropub serving creative beers and polished comfort food in a stylish but relaxed setting.
Beloved local pizzeria known for thin crust, square-cut Columbus-style pies in a casual neighborhood setting.
Moderate for a U.S. city: hotels, dining, and transit usually cost less than New York or Chicago, but more than smaller Midwest towns.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee at cafes if service is provided.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Columbus, OH.
Find answers to the most common questions about traveling from Syracuse, NY to Columbus, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbus, OH, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to Columbus, OH buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to Columbus, E Town St (Bus Station) station pair, with some services arriving at Columbus, E Mound St (Akili Christian High School). Use this guide to compare Syracuse, NY and Columbus, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Columbus, E Town St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Town St (Bus Station). ATMs are available at Columbus, E Town St (Bus Station).
Ticket office support is available at Columbus, E Town St (Bus Station).
Available at Columbus, E Town St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Town St (Bus Station): Wheelchair accessible bus platforms.
Columbus, E Mound St (Akili Christian High School) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Columbus, E Mound St (Akili Christian High School). ATMs are available at Columbus, E Mound St (Akili Christian High School).
Ticket office support is available at Columbus, E Mound St (Akili Christian High School).
Available at Columbus, E Mound St (Akili Christian High School): Parking, Taxis, WC.
Accessibility facilities are available at Columbus, E Mound St (Akili Christian High School): Wheelchair accessible buses available.
Check bus stations information for Syracuse, NY and Columbus, OH, including where buses depart and arrive on this route.