- Must visit
USS Midway Museum
Museum aboard the historic aircraft carrier USS Midway with restored aircraft, flight deck exhibits, and audio tours on San Diego Bay.
Omio recommends booking the train as it is the most popular option from Simi Valley, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 4h 16m. The ticket price range depends on the travel mode: a bus costs an average of $43, and a flight costs an average of $167.
Distance: 142 miles (229 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$43 Average price Cheapest | $43 Average price | $440 Average price |
5h 44m Average total duration 5h 14m Onboard + 30m Additional time* | 4h 46m Average total duration Fastest 4h 16m Onboard + 30m Additional time* | 7h 44m Average total duration 4h 44m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Simi Valley, CA to San Diego, CA:
A bus is $0.04 (€0.03) less than a train for this route with tickets for a train from Simi Valley, CA to San Diego, CA costing on average $43 (€35).
A bus is $397 (€324) less than a flight for this route with tickets for a flight from Simi Valley, CA to San Diego, CA costing on average $440 (€360).
Other travel options to San Diego, CA take longer:
Flight takes on average 4h 44m.
Bus takes on average 5h 14m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 04:41PM | Arrival Time 09:55PM | Duration 5h14 | Departure days Sun | Cheapest price $43 |
Compare train, flight, and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Simi Valley, CA to San Diego, CA run on average 5 times per day, taking around 5h 14m. Cheap bus tickets for this journey start at $43 (€35) but you can travel from only $42 (€35) by train.
The earliest bus runs at 03:50, the last at 20:49. The fastest bus covers the 142 miles (229 km) distance in 5h 14m.
Distance 142 miles (229 km) |
Average bus duration 5h 14m |
Cheapest ticket price $43 (€35) |
Buses per day 5 |
Fastest bus 5h 14m |
First bus 3:50 AM |
Last bus 8:49 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Wed |
Best time to book 5 days |
Discover the best of San Diego — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego trip today.
Museum aboard the historic aircraft carrier USS Midway with restored aircraft, flight deck exhibits, and audio tours on San Diego Bay.
Balboa Park art museum known for Spanish old masters, South Asian works, and rotating exhibitions in a landmark building.
Leading contemporary art museum with major postwar and current works, especially strong in Southern California and Pacific Rim artists.
Vast cultural park with gardens, museums, Spanish Colonial Revival architecture, walking paths, and some of San Diego's best photo spots.
Scenic cove known for sea lions, clear water, coastal cliffs, and highly shareable sunset and ocean-view walks.
Wide sandy beach beside the Hotel del Coronado, popular for walking, photography, and classic Southern California scenery.
Beer-battered or grilled local fish in tortillas, usually topped with cabbage, crema, and salsa. A signature coastal San Diego staple with strong Baja influence.
A San Diego original burrito filled with carne asada, fries, cheese, and salsa. It is one of the city’s most iconic late-night and casual foods.
French fries topped with carne asada, cheese, guacamole, sour cream, and salsa. This indulgent dish is strongly associated with San Diego taco shop culture.
Popular waterfront seafood restaurant serving fresh local catch, fish tacos, and sandwiches in a relaxed harbor setting near the fishing fleet.
Historic, no-frills Mexican restaurant famous for house-made tortillas, rolled tacos, and comforting traditional plates. A beloved local institution with a classic atmosphere.
Iconic casual spot in Ocean Beach known for oversized burgers, fries, and a lively beach-town vibe. A long-standing San Diego favorite.
Prices are high by U.S. standards, especially for hotels, dining, and parking near the coast and downtown.
Tip 18-20% at restaurants, 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet.
Find answers to the most common questions about traveling from Simi Valley, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

Most Simi Valley, CA to San Diego, CA buses use the San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop) to San Diego, Congress Street (Old Town Park) station pair, with some services arriving at La Jolla, UCSD Health La Jolla Station. Use this guide to compare Simi Valley, CA and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need