- Must visit
Museo del Prado
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Cheapest price
$39
Average price
$53
Fastest journey
5 h
Average duration
5 h 23 m
Buses per day
9
Distance
339 km
The best way to find a cheap bus ticket from Santander to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Madrid will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $39.
Of the 9 buses that leave Santander for Madrid on Wed, Jul 29, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 29 the direct buses cover the 339 km distance in an average of 5 h 23 m but if you time it right, some buses will get you there in just 5 h .
On Wed, Jul 29 the slowest buses will take 5 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Supra Economy
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NormalOmio recommends booking the train as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price take the train with prices starting from $16. For those with little time consider booking a flight which can get you there in 2h 41m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of $16, and a flight costs an average of $49.
Distance: 210 miles (339 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$54 Average price | $31 Average price Cheapest | $254 Average price | $65 Average price (fuel + tolls) |
6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 4h 47m Average total duration 4h 17m Onboard + 30m Additional time* | 5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* | 4h 41m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santander to Madrid:
A train is $22 (€22) less than a bus for this route with tickets for a bus from Santander to Madrid costing on average $54 (€54).
A train is $222 (€222) less than a flight for this route with tickets for a flight from Santander to Madrid costing on average $254 (€254).
Other travel options to Madrid take longer:
Train takes on average 4h 17m.
Bus takes on average 5h 52m.
Tickets start at around $54 (€54) compared to roughly $65 (€65) in fuel and tolls — a saving of about $12 (€12). The journey takes 5h 52m versus 4h 41m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Alsa, Alsa Supra, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Alsa | Departure Time 12:45AM | Arrival Time 06:15AM | Duration 5h30 | Departure days Mon, Fri, Sat, Sun | Cheapest price $60 |
Operator BlaBlaCar | Departure Time 05:00AM | Arrival Time 09:40AM | Duration 4h40 | Departure days Sat | Cheapest price $29 |
Operator Alsa | Departure Time 06:00AM | Arrival Time 10:40AM | Duration 4h40 | Departure days Thu | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 12:40PM | Duration 5h10 | Departure days Fri | Cheapest price $25 |
Operator Alsa | Departure Time 08:00AM | Arrival Time 01:50PM | Duration 5h50 | Departure days Everyday | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 01:30PM | Duration 5h10 | Departure days Wed | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 01:50PM | Duration 4h50 | Departure days Wed, Sat, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 07:10AM | Duration 21h40 | Departure days Everyday | Cheapest price $78 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 02:40PM | Duration 5h10 | Departure days Thu, Fri | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 02:20PM | Duration 4h20 | Departure days Mon, Sat, Sun | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 10:10AM | Arrival Time 02:50PM | Duration 4h40 | Departure days Thu | Cheapest price $23 |
Operator Alsa | Departure Time 10:30AM | Arrival Time 04:45PM | Duration 6h15 | Departure days Mon, Sat, Sun | Cheapest price $41 |
Operator Alsa | Departure Time 12:00PM | Arrival Time 05:45PM | Duration 5h45 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $41 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 07:00PM | Duration 5h00 | Departure days Wed | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 06:50PM | Duration 4h20 | Departure days Mon, Wed | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 06:50PM | Duration 3h50 | Departure days Tue, Sun | Cheapest price $25 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 07:30PM | Duration 4h00 | Departure days Mon, Thu | Cheapest price $23 |
Operator Alsa | Departure Time 03:30PM | Arrival Time 09:15PM | Duration 5h45 | Departure days Everyday | Cheapest price $41 |
Operator Alsa | Departure Time 04:00PM | Arrival Time 10:45PM | Duration 6h45 | Departure days Mon, Fri | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 08:20PM | Duration 4h20 | Departure days Mon, Thu, Sat | Cheapest price $19 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 09:20PM | Duration 4h20 | Departure days Fri, Sun | Cheapest price $22 |
Operator BlaBlaCar | Departure Time 05:10PM | Arrival Time 10:20PM | Duration 5h10 | Departure days Mon | Cheapest price $28 |
Operator Alsa | Departure Time 05:30PM | Arrival Time 11:00PM | Duration 5h30 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $39 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 09:30PM | Duration 4h00 | Departure days Tue, Wed, Fri | Cheapest price $25 |
Operator BlaBlaCar | Departure Time 05:40PM | Arrival Time 09:40PM | Duration 4h00 | Departure days Sat | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 11:00PM | Duration 5h00 | Departure days Tue, Fri, Sun | Cheapest price $22 |
Operator BlaBlaCar | Departure Time 06:10PM | Arrival Time 10:10PM | Duration 4h00 | Departure days Tue | Cheapest price $25 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 01:20PM | Duration 18h25 | Departure days Everyday | Cheapest price $68 |
Operator BlaBlaCar | Departure Time 07:10PM | Arrival Time 12:00AM | Duration 4h50 | Departure days Tue | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 07:30PM | Arrival Time 12:20AM | Duration 4h50 | Departure days Thu | Cheapest price $23 |
The table below shows live departures for Santander to Madrid buses for today, Tuesday, July 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Normal | 8:00 AM Santander, Estación de Autobuses | 5h50 | 1:50 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Normal | 8:00 AM Santander, Estación de Autobuses | 5h40 | 1:40 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
FlixBus · FlixBus | 9:30 AM Santander, Estación de Autobuses | 21h40 | 7:10 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
Normal | 3:30 PM Santander, Estación de Autobuses | 5h45 | 9:15 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Normal | 5:30 PM Santander, Estación de Autobuses | 5h30 | 11:00 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 6:55 PM Santander, Estación de Autobuses | 18h25 | 1:20 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santander to Madrid run on average 15 times per day, taking around 5h 52m. Cheap bus tickets for this journey start at $33 (€33) but you can travel from only $16 (€16) by train.
There are 12 buses per day. The earliest bus runs at 00:30, the last at 23:45. The fastest bus covers the 210 miles (339 km) distance in 5h 15m.
Distance 210 miles (339 km) |
Average bus duration 5h 52m |
Cheapest ticket price $33 (€33) |
Buses per day 15 |
Direct buses 12 |
Fastest bus 5h 15m |
First bus 12:30 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 91 days |
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Leading modern art museum best known for Picasso’s Guernica, plus major works by Dalí and Miró.
Celebrated collection of European masters from Van Eyck to Hopper in a refined palace setting.
Madrid’s most famous park offers gardens, a boating lake, monuments, and relaxed walks in the city center.
Lively grand avenue known for architecture, shopping, theaters, and nonstop energy from day to night.
Elegant boulevard linking major museums and landmarks, ideal for a classic central Madrid walk.
A hearty chickpea stew with meats, vegetables, and broth, especially traditional in Madrid and often served in stages.
Crisp fried squid rings served in a baguette roll. This iconic Madrid street food is especially linked to bars around Plaza Mayor.
Tripe stew with chorizo and morcilla in a rich sauce. A classic old Madrid tavern dish with deep local roots.
Refined two-Michelin-star dining focused on seasonal Spanish produce, with elegant modern cooking in a polished fine-dining room.
Traditional Madrid restaurant known for cocido madrileño served in stages, with an old-school dining room and loyal local following.
Historic century-old tavern famed for roast suckling pig and Castilian dishes in a classic, wood-lined setting near Plaza Mayor.
Moderate for Western Europe: hotels vary, dining is reasonable, and public transport is good value for tourists.
Tipping is modest: round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, small change is enough.
Official public transport app
Madrid Estación Sur de Autobuses -> Puerta del Sol
Find answers to the most common questions about traveling from Santander to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Most Santander to Madrid buses use the Santander, Estación de Autobuses to Madrid, Avenida de América station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Santander and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Madrid, Avenida de América is 3 km from Madrid city centre. Public transport options include:
Madrid, Avenida de América has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Rincón (0.5 km), La Vaca Argentina (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and on the second floor.
Ticket office support is available at Madrid, Avenida de América.
Available at Madrid, Avenida de América: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Avenida de América: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food options include: Rodilla, Mahoudrid
ATMs are aTMs located throughout T4, major cards accepted .
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Here are some other resources that might have the information you need