The cheapest and fastest buses from Santander to Madrid
Cheapest price
$25
Average price
$54
Fastest journey
4 h
Average duration
4 h 12 m
Buses per day
20
Distance
339 km
The best way to find a cheap bus ticket from Santander to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Madrid will cost around $54 if you buy it on the day, but the cheapest tickets can be found for only $25.
Of the 20 buses that leave Santander for Madrid on Mon, Dec 15, 17 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 15 the direct buses cover the 339 km distance in an average of 4 h 12 m but if you time it right, some buses will get you there in just 4 h .
On Mon, Dec 15 the slowest buses will take 4 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Santander to Madrid
Omio recommends booking the train as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price take the train with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 32m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of €25, and a flight costs an average of €60.
Distance: 210 miles (339 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€72 Average price | €53 Average price Cheapest | €290 Average price |
8h 36m Average total duration 8h 6m Onboard + 30m Additional time* | 4h 55m Average total duration 4h 25m Onboard + 30m Additional time* | 4h 32m Average total duration Fastest 1h 32m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Santander to Madrid Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Alsa | Departure Time 12:45AM | Arrival Time 06:30AM | Duration 5h45 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $59 |
Operator Alsa | Departure Time 01:00AM | Arrival Time 06:30AM | Duration 5h30 | Departure days Mon, Wed, Fri, Sat | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 05:30AM | Arrival Time 09:40AM | Duration 4h10 | Departure days Tue | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 10:20AM | Duration 4h20 | Departure days Fri | Cheapest price $32 |
Operator BlaBlaCar | Departure Time 06:30AM | Arrival Time 10:20AM | Duration 3h50 | Departure days Sat | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 12:20PM | Duration 5h20 | Departure days Thu | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 11:20AM | Duration 3h50 | Departure days Tue | Cheapest price $34 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 12:10PM | Duration 4h10 | Departure days Mon, Wed | Cheapest price $29 |
Operator Alsa | Departure Time 08:00AM | Arrival Time 01:40PM | Duration 5h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 12:30PM | Duration 4h00 | Departure days Mon, Fri | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 08:40AM | Arrival Time 12:40PM | Duration 4h00 | Departure days Sat | Cheapest price $35 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 07:10AM | Duration 21h45 | Departure days Mon, Tue, Wed, Thu | Cheapest price $89 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 07:10AM | Duration 21h40 | Departure days Fri, Sat | Cheapest price $109 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 01:40PM | Duration 4h10 | Departure days Fri | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 02:00PM | Duration 4h00 | Departure days Tue, Wed, Thu, Sat | Cheapest price $29 |
Operator Alsa | Departure Time 10:30AM | Arrival Time 04:45PM | Duration 6h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 03:10PM | Duration 4h10 | Departure days Fri | Cheapest price $37 |
Operator Alsa | Departure Time 12:00PM | Arrival Time 05:45PM | Duration 5h45 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 07:10PM | Duration 5h10 | Departure days Mon, Wed, Sat | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 06:30PM | Duration 4h00 | Departure days Sun | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 03:20PM | Arrival Time 08:20PM | Duration 5h00 | Departure days Sun | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 03:30PM | Arrival Time 08:10PM | Duration 4h40 | Departure days Mon, Thu | Cheapest price $27 |
Operator Alsa | Departure Time 03:30PM | Arrival Time 08:45PM | Duration 5h15 | Departure days Everyday | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 03:40PM | Arrival Time 07:50PM | Duration 4h10 | Departure days Sat | Cheapest price $43 |
Operator Alsa | Departure Time 04:00PM | Arrival Time 10:45PM | Duration 6h45 | Departure days Everyday | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 08:20PM | Duration 4h20 | Departure days Fri | Cheapest price $35 |
Operator BlaBlaCar | Departure Time 04:30PM | Arrival Time 09:30PM | Duration 5h00 | Departure days Sun | Cheapest price $34 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 09:10PM | Duration 4h10 | Departure days Wed, Sun | Cheapest price $32 |
Operator Alsa | Departure Time 05:30PM | Arrival Time 11:00PM | Duration 5h30 | Departure days Everyday | Cheapest price $54 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 09:40PM | Duration 4h10 | Departure days Thu | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 11:50PM | Duration 5h50 | Departure days Tue, Wed | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 06:40PM | Arrival Time 11:00PM | Duration 4h20 | Departure days Mon | Cheapest price $25 |
Operator FlixBus | Departure Time 06:50PM | Arrival Time 01:20PM | Duration 18h30 | Departure days Mon, Tue, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 01:20PM | Duration 18h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price $82 |
Live departures
Santander to Madrid bus times
The table below shows live departures for Santander to Madrid buses for today, Sunday, December 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Supra Economy | 2:30 PM Santander, Estación de Autobuses | 5h15 | 7:45 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Supra Economy | 2:30 PM Santander, Estación de Autobuses | 5h00 | 7:30 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Normal · Normal | 3:00 PM Santander, Estación de Autobuses | 6h45 | 9:45 PM Madrid, Calle de la Princesa / Paseo de Moret (Moncloa) | 1 transfer | |
Normal | 4:30 PM Santander, Estación de Autobuses | 5h30 | 10:00 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 5:50 PM Santander, Estación de Autobuses | 18h30 | 12:20 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
Supra Economy | 11:45 PM Santander, Estación de Autobuses | 5h30 | 5:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Supra Economy | 11:45 PM Santander, Estación de Autobuses | 5h45 | 5:30 AM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
| Monday, December 15 | |||||
Normal | 12:00 AM Santander, Estación de Autobuses | 5h15 | 5:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Normal | 12:00 AM Santander, Estación de Autobuses | 5h30 | 5:30 AM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Normal | 7:00 AM Santander, Estación de Autobuses | 5h40 | 12:40 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Normal | 7:00 AM Santander, Estación de Autobuses | 5h50 | 12:50 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 8:25 AM Santander, Estación de Autobuses | 21h45 | 6:10 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santander to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 14
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Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
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Dec 31
Jan 01
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Jan 03
Journey information
Overview: Bus from Santander to Madrid
Buses from Santander to Madrid run on average 15 times per day, taking around 8h 6m. Cheap bus tickets for this journey start at $40 (€32) but you can travel from only $31 (€25) by train.
There are 12 buses per day. The earliest bus runs at 00:10, the last at 23:45. The fastest bus covers the 210 miles (339 km) distance in 5h 15m.
Distance 210 miles (339 km) |
Average bus duration 8h 6m |
Cheapest ticket price $40 (€32) |
Buses per day 15 |
Direct buses 12 |
Fastest bus 5h 15m |
First bus 00:10 |
Last bus 23:45 |
Bus providers: Alsa, Alsa Supra, BlaBlaCar, FlixBus from Santander to MadridYou can travel by bus between Santander to Madrid with Alsa, Alsa Supra, BlaBlaCar, FlixBus for as low as $31 (€25). When you search for schedules and tickets, Omio will show you the best journey
Alsa
Alsa Supra
FlixBus
BlaBlaCar
FAQs: Bus from Santander to Madrid
Find answers to the most common questions about traveling from Santander to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Santander, Estación de Autobuses, which is located around 1.1 miles (1.8 km) away from the city centre, and they get off the bus at Madrid, Avenida de América, located 3.2 miles (5.2 km) away from the city centre.
- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- Alsa Supra
- Assistance
- Priority boarding
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
- Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
- Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
- Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
- Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
- Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
- Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
- Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
- Attend a flamenco show to experience traditional Spanish dance and music
- Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- Alsa Supra
- You can cancel your ticket up to 48 hours before departure for a partial refund. Within 48 hours, a fee applies.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Santander to Madrid, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- Alsa Supra
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- Alsa Supra
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- Larger pets must travel in the hold.
- Alsa Supra
- Small pets allowed in carriers
- Guide dogs travel for free.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Santander to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Rincón (0.5 km)
- La Vaca Argentina (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 200, 114, 115, 122 Metro: 4, 6, 7, 9
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
- 06:00-23:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 1, 2, 44, 82, 132, C1, C2 Metro: 3, 6
Most popular bus connections from Santander
More options for your journey from Santander to Madrid
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