- Must visit
Museo Nacional del Prado
Spain’s premier art museum, famed for masterpieces by Velázquez, Goya, and El Greco. A cornerstone of Madrid’s Golden Triangle of Art and a top priority for first-time visitors.
Cheapest price
$45
Average price
$80
Fastest journey
5 h
Average duration
5 h 24 m
Buses per day
8
Distance
339 km
The best way to find a cheap bus ticket from Santander to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Madrid will cost around $80 if you buy it on the day, but the cheapest tickets can be found for only $45.
Of the 8 buses that leave Santander for Madrid on Sat, Jun 13, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 13 the direct buses cover the 339 km distance in an average of 5 h 24 m but if you time it right, some buses will get you there in just 5 h .
On Sat, Jun 13 the slowest buses will take 5 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Normal · Normal
Normal
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Supra Economy
Supra Economy
Supra Economy
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Normal
NormalOmio recommends booking the train as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price take the train with prices starting from $20. For those with little time consider booking a flight which can get you there in 2h 41m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of $20, and a flight costs an average of $60.
Distance: 210 miles (339 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$66 Average price | $39 Average price Cheapest | $312 Average price | $80 Average price (fuel + tolls) |
6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 4h 47m Average total duration 4h 17m Onboard + 30m Additional time* | 5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* | 4h 41m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santander to Madrid:
A train is $27 (€22) less than a bus for this route with tickets for a bus from Santander to Madrid costing on average $66 (€54).
A train is $274 (€222) less than a flight for this route with tickets for a flight from Santander to Madrid costing on average $312 (€254).
Other travel options to Madrid take longer:
Train takes on average 4h 17m.
Bus takes on average 5h 52m.
Tickets start at around $66 (€54) compared to roughly $80 (€65) in fuel and tolls — a saving of about $14 (€12). The journey takes 5h 52m versus 4h 41m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Alsa, Alsa Supra, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Alsa | Departure Time 12:45AM | Arrival Time 06:15AM | Duration 5h30 | Departure days Tue, Wed, Thu, Sun | Cheapest price $50 |
Operator Alsa | Departure Time 01:00AM | Arrival Time 06:30AM | Duration 5h30 | Departure days Tue, Wed, Sun | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 05:00AM | Arrival Time 09:10AM | Duration 4h10 | Departure days Mon | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 07:10AM | Arrival Time 12:00PM | Duration 4h50 | Departure days Tue | Cheapest price $30 |
Operator BlaBlaCar | Departure Time 07:20AM | Arrival Time 11:40AM | Duration 4h20 | Departure days Thu | Cheapest price $38 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 01:20PM | Duration 5h20 | Departure days Sat | Cheapest price $39 |
Operator Alsa | Departure Time 08:00AM | Arrival Time 01:50PM | Duration 5h50 | Departure days Mon, Thu, Sun | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 09:20AM | Arrival Time 02:10PM | Duration 4h50 | Departure days Wed | Cheapest price $33 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 07:10AM | Duration 21h45 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $127 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 01:30PM | Duration 4h00 | Departure days Wed, Sun | Cheapest price $25 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 02:20PM | Duration 4h20 | Departure days Thu | Cheapest price $35 |
Operator Alsa | Departure Time 10:30AM | Arrival Time 04:45PM | Duration 6h15 | Departure days Tue, Wed, Thu, Sun | Cheapest price $45 |
Operator BlaBlaCar | Departure Time 10:50AM | Arrival Time 04:00PM | Duration 5h10 | Departure days Tue | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 03:30PM | Duration 4h30 | Departure days Tue, Sun | Cheapest price $22 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 04:40PM | Duration 5h10 | Departure days Wed, Sat | Cheapest price $30 |
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 04:10PM | Duration 4h30 | Departure days Tue | Cheapest price $28 |
Operator Alsa | Departure Time 12:00PM | Arrival Time 05:30PM | Duration 5h30 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 04:10PM | Duration 4h10 | Departure days Sun | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 05:00PM | Duration 4h30 | Departure days Thu | Cheapest price $33 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 06:00PM | Duration 4h00 | Departure days Wed, Thu | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 07:10PM | Duration 4h40 | Departure days Sat | Cheapest price $39 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 07:00PM | Duration 4h00 | Departure days Thu | Cheapest price $31 |
Operator Alsa | Departure Time 03:30PM | Arrival Time 08:45PM | Duration 5h15 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $53 |
Operator Alsa | Departure Time 04:00PM | Arrival Time 10:45PM | Duration 6h45 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $45 |
Operator BlaBlaCar | Departure Time 04:00PM | Arrival Time 09:10PM | Duration 5h10 | Departure days Mon | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 10:00PM | Duration 5h00 | Departure days Mon | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 05:10PM | Arrival Time 10:00PM | Duration 4h50 | Departure days Tue | Cheapest price $27 |
Operator BlaBlaCar | Departure Time 05:20PM | Arrival Time 09:50PM | Duration 4h30 | Departure days Wed | Cheapest price $31 |
Operator Alsa | Departure Time 05:30PM | Arrival Time 11:00PM | Duration 5h30 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $49 |
Operator BlaBlaCar | Departure Time 05:30PM | Arrival Time 09:30PM | Duration 4h00 | Departure days Sun | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 10:40PM | Duration 4h40 | Departure days Sat | Cheapest price $35 |
Operator FlixBus | Departure Time 06:50PM | Arrival Time 01:20PM | Duration 18h30 | Departure days Everyday | Cheapest price $95 |
Operator BlaBlaCar | Departure Time 07:30PM | Arrival Time 12:20AM | Duration 4h50 | Departure days Fri, Sun | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 08:30PM | Arrival Time 12:50AM | Duration 4h20 | Departure days Fri | Cheapest price $36 |
The table below shows live departures for Santander to Madrid buses for tomorrow, Saturday, June 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:25 AM Santander, Estación de Autobuses | 21h45 | 7:10 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
Normal | 12:00 PM Santander, Estación de Autobuses | 5h45 | 5:45 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Normal | 12:00 PM Santander, Estación de Autobuses | 5h30 | 5:30 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Supra Economy | 3:30 PM Santander, Estación de Autobuses | 5h15 | 8:45 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Supra Economy | 3:30 PM Santander, Estación de Autobuses | 5h00 | 8:30 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Normal · Normal | 4:00 PM Santander, Estación de Autobuses | 6h45 | 10:45 PM Madrid, Calle de la Princesa / Paseo de Moret (Moncloa) | 1 transfer | |
Normal | 5:30 PM Santander, Estación de Autobuses | 5h30 | 11:00 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 6:50 PM Santander, Estación de Autobuses | 18h30 | 1:20 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santander to Madrid run on average 15 times per day, taking around 5h 52m. Cheap bus tickets for this journey start at $41 (€33) but you can travel from only $20 (€16) by train.
There are 12 buses per day. The earliest bus runs at 00:30, the last at 23:45. The fastest bus covers the 210 miles (339 km) distance in 5h 15m.
Distance 210 miles (339 km) |
Average bus duration 5h 52m |
Cheapest ticket price $41 (€33) |
Buses per day 15 |
Direct buses 12 |
Fastest bus 5h 15m |
First bus 12:30 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 91 days |
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
Spain’s premier art museum, famed for masterpieces by Velázquez, Goya, and El Greco. A cornerstone of Madrid’s Golden Triangle of Art and a top priority for first-time visitors.
Madrid’s leading modern art museum, best known for Picasso’s Guernica alongside major works by Dalí and Miró. Essential for modern and contemporary art lovers.
A major museum spanning European painting from the Renaissance to the 20th century. Its broad collection complements the Prado and Reina Sofía perfectly.
Madrid’s most famous park, ideal for walking, boating, and relaxing among monuments and formal gardens. A top city experience for nearly every visitor.
Madrid’s best-known avenue, lined with historic architecture, theaters, shops, and rooftop views. Energetic by day and night, it is one of the city’s defining walks.
The symbolic heart of Madrid and a major meeting point, home to the Kilómetro Cero marker and famous public celebrations. Constantly busy and central.
Madrid’s signature chickpea stew, traditionally served in stages with broth, vegetables, chickpeas, and assorted meats. It is one of the city’s most emblematic comfort dishes.
A classic Madrid sandwich of fried squid rings in crusty bread, especially associated with bars around Plaza Mayor. It is a simple local staple and iconic snack.
A rich traditional stew made with tripe, chorizo, and morcilla in a paprika-forward sauce. It is a historic tavern dish closely linked to Madrid cuisine.
Prestigious flamenco venue with acclaimed dining, known for refined Spanish cuisine in an intimate historic setting. It combines performance and high-end gastronomy.
Historic traditional restaurant famous for roast suckling pig and Castilian classics. It offers an old-world atmosphere and is one of Madrid’s most iconic dining rooms.
Well-known classic restaurant celebrated for huevos rotos and traditional Spanish cooking. It is a long-established spot with a lively, polished tavern feel.
Moderate for Western Europe. Museums and transport are reasonable, while central hotels and fine dining cost more.
Service is usually included. Locals often round up or leave EUR 1-2 in cafés and 5-10% at restaurants for very good service. Tipping is appreciated, not required.
Official public transport app
Madrid, Estación Sur de Autobuses -> Puerta del Sol, Madrid
Find answers to the most common questions about traveling from Santander to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

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