Travel Information
Compare train, bus, and flight for Santander to Madrid
Omio recommends booking the flight as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price, take the train, with an average ticket price of $31 For those with little time, consider booking a flight, which has an average total journey time of 3h 12m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a train costs an average of $31, while a flight costs an average of $251.
Distance: 210 miles (339 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$251 Average price | $31 Average price Cheapest | $59 Average price | $81 Average price (fuel + tolls) |
3h 12m Average total duration Fastest 1h 12m Onboard + 2h 0m Additional time* | 5h 19m Average total duration 4h 49m Onboard + 30m Additional time* | 7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 4h 41m Average total duration (door-to-door) |
1.0 - 2.0kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.8kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santander to Madrid:
A train is $28 less than a bus for this route with tickets for a bus from Santander to Madrid costing on average $59.
A train is $219 less than a flight for this route with tickets for a flight from Santander to Madrid costing on average $251.
Other travel options to Madrid take longer:
Train takes on average 5h 19m.
Bus takes on average 7h 36m.
You'll arrive about 3h 29m sooner (1h 12m by flight vs 4h 41m by car). Tickets start at around $251 compared to roughly $81 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Santander to Madrid
How to get from Santander to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Santander to Madrid is by taking a bus because it’s the best combination of price and speed.
Normal5:30 PM5h30Santander, Estación de Autobuses11:00 PMMadrid, Intercambiador de Avenida de América$481One-way0 transfers
Cheapest
Normal5:30 PM5h30Santander, Estación de Autobuses11:00 PMMadrid, Intercambiador de Avenida de América$481One-way0 transfers
Fastest
IB4945:40 PM1h10Santander Airport6:50 PMMadrid Barajas Airport$2591One-way0 transfers
Other options
18102+
180049:20 AM8h09Santander station5:29 PMMadrid Príncipe Pío$611One-way1 transfer
18102+
180129:20 AM9h35Santander station6:55 PMMadrid Príncipe Pío$611One-way1 transfer
04072+
180047:05 AM10h24Santander station5:29 PMMadrid Príncipe Pío$611One-way1 transfer
Normal1:00 AM5h15Santander, Estación de Autobuses6:15 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$501One-way0 transfers
Normal1:00 AM5h30Santander, Estación de Autobuses6:30 AMMadrid, Intercambiador de Avenida de América$501One-way0 transfers
Normal8:00 AM5h40Santander, Estación de Autobuses1:40 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$501One-way0 transfers
IB10609:20 AM1h10Santander Airport10:30 AMMadrid Barajas Airport$3211One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Santander to Madrid
The Best Way According to our Users
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FAQs: Travel from Santander to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Madrid.

This is compared to other travel options from Santander to Madrid:
A train is $28 less than a bus for this route with tickets for a bus from Santander to Madrid costing on average $59.
A train is $219 less than a flight for this route with tickets for a flight from Santander to Madrid costing on average $251.
Other travel options to Madrid take longer:
Train takes on average 5h 19m.
Bus takes on average 7h 36m.
- Around 15 trains per day.
- Around 13 buses per day.
- Around 3 flights per day.
However, we recommend checking specific travel dates for your route between Santander and Madrid as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Madrid Barajas Airport.
- Trains mostly depart from Santander station and arrive in Madrid Chamartín.
- Buses mostly depart from Santander, Estación de Autobuses and arrive in Madrid, Intercambiador de Avenida de América.
- Travel with Iberia, Air Nostrum, Vueling, Air Europa to go to Madrid by flight.
- Travel with Alsa, Alsa Supra, BlaBlaCar, FlixBus to go to Madrid by bus.
- Travel with Renfe ALVIA, Renfe INTERCITY, Renfe, Renfe MD, Renfe Viajeros to go to Madrid by train.
- 3 direct flights per day with Iberia, Air Nostrum.
- 11 direct buses per day with Alsa, Alsa Supra, BlaBlaCar.
- 3 direct trains per day with Renfe Viajeros.
Travelling from Santander to Madrid: related information
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