- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.






Cheapest price
$19
Average price
$20
Fastest journey
59m
Average duration
1h 20m
Trains per day
6
Distance
56 km
Omio recommends booking the bus as it is the most popular option from Santa Clara, CA to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $10. For those with little time consider booking a bus which can get you there in 58m. The ticket price range depends on the travel mode: a bus costs an average of $10, and a train costs an average of $27.
Distance: 38 miles (62 km)
Most popular Bus | Train | Driving |
|---|---|---|
$15 Average price Cheapest | $27 Average price | $10 Average price (fuel + tolls) |
1h 28m Average total duration Fastest 58m Onboard + 30m Additional time* | 2h 9m Average total duration 1h 39m Onboard + 30m Additional time* | 54m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Clara, CA to San Francisco, CA:
A bus is $13 (€11) less than a train for this route with tickets for a train from Santa Clara, CA to San Francisco, CA costing on average $27 (€23).
Other travel options to San Francisco, CA take longer:
Train takes on average 1h 39m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:05AM | Arrival Time 02:05AM | Duration 1h00 | Departure days Tue, Wed, Thu | Cheapest price $10 |
Operator Greyhound | Departure Time 05:45AM | Arrival Time 07:10AM | Duration 1h25 | Departure days Fri | Cheapest price $14 |
Operator Greyhound | Departure Time 12:35PM | Arrival Time 02:15PM | Duration 1h40 | Departure days Thu, Sat | Cheapest price $15 |
Operator Greyhound | Departure Time 08:25PM | Arrival Time 10:05PM | Duration 1h40 | Departure days Fri | Cheapest price $13 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 12:35AM | Duration 1h00 | Departure days Wed | Cheapest price $12 |
The table below shows live departures for Santa Clara, CA to San Francisco, CA buses for tomorrow, Wednesday, July 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:05 AM Santa Clara, CA | 1h00 | 2:05 AM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santa Clara, CA to San Francisco, CA run on average 6 times per day, taking around 58m. Cheap bus tickets for this journey start at $10 (€8) if you book in advance.
There are 4 buses per day. The earliest bus runs at 05:20, the last at 23:50. The fastest bus covers the 38 miles (62 km) distance in 1h 0m.
Distance 38 miles (62 km) |
Average bus duration 58m |
Cheapest ticket price $10 (€8) |
Buses per day 6 |
Direct buses 4 |
Fastest bus 1h 0m |
First bus 5:20 AM |
Last bus 11:50 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 1 day |
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Santa Clara, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

Most Santa Clara, CA to San Francisco, CA buses use the San José, Cahill Street (Diridon Station) to San Francisco, Townsend Street / 5th Street station pair, with some services arriving at San Francisco, Transit Center Bay 29. Use this guide to compare Santa Clara, CA and San Francisco, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need