Santa Clara, CA to San Diego, CA bus

Wed, Oct 14
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
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The cheapest and fastest buses from Santa Clara, CA to San Diego, CA

Showing times, prices and bookable tickets for Oct 14

Cheapest price on Oct 14

€81

Average ticket price on Oct 14

€86

Fastest journey on Oct 14

11 h 35 m

Average journey duration on Oct 14

12 h 38 m

Buses on Oct 14

2

Distance

676 km

Cheap tickets

The best way to find a cheap bus ticket from Santa Clara, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Santa Clara, CA to San Diego, CA will cost around €86 if you buy it on the day, but the cheapest tickets can be found for only €81.

Fast buses

On Wed, Oct 14, we found 2 buses from Santa Clara, CA to San Diego, CA, including 2 direct services.

On Wed, Oct 14 the direct buses cover the 676 km distance in an average of 12 h 38 m but if you time it right, some buses will get you there in just 11 h 35 m .

On Wed, Oct 14 the slowest buses will take 13 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    3:35 PM13h40
    Santa Clara, CA
    5:15 AMSan Diego, CA
    €811One-way
    0 transfers
  • Amtrak
    2:00 AM11h35
    Santa Clara, CA
    1:35 PMSan Diego, CA
    €901One-way
    0 transfers

Journey information

Overview: Bus from Santa Clara, CA to San Diego, CA

USAUSA
USAUSA
Icon of bus

Take a bus from Santa Clara, CA to San Diego, CA and enjoy the approximately 420 miles (676 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest bus runs at 00:05, the last at 23:45.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €150
Distance
420 miles (676 km)
First bus
12:05 AM
Last bus
11:45 PM
Cheapest Month
Nov
Cheapest Day
Mon
High Season
Oct - Dec
Low Season
Jul - Sep
Best time to book
7 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €150

Santa Clara, CA to San Diego, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Amtrak
Departure Time
01:00AM
Arrival Time
12:35PM
Duration
11h35
Departure days
Fri, Sat
Cheapest price
€93
Operator
Amtrak
Departure Time
02:00AM
Arrival Time
01:35PM
Duration
11h35
Departure days
Thu
Cheapest price
€90
Operator
FlixBus
Departure Time
03:35PM
Arrival Time
05:15AM
Duration
13h40
Departure days
Wed
Cheapest price
€81
Operator
FlixBus
Departure Time
05:25PM
Arrival Time
06:15AM
Duration
12h50
Departure days
Mon
Cheapest price
€43

Live departures

Santa Clara, CA to San Diego, CA bus times

The table below shows live departures for Santa Clara, CA to San Diego, CA buses for tomorrow, Wednesday, October 14. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Amtrak2:00 AM Santa Clara, CA
11h35
1:35 PM San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Complete guide to San Diego, CA

Things to do in San Diego, CA

Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.

  • Must visit

San Diego Museum of Art

Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.

  • Must visit

Museum of Contemporary Art San Diego

Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.

  • Must visit

USS Midway Museum

Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.

US Dollar ($)

San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$25-45 per person for a mid-range meal.
Fine dining
$75+ per person for upscale dining.
Coffee
$4-6 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.

FAQs: Bus from Santa Clara, CA to San Diego, CA

Find answers to the most common questions about traveling from Santa Clara, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
The earliest bus from Santa Clara, CA to San Diego, CA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Santa Clara, CA to San Diego, CA leaves at 11:45 PM.
When departing from Santa Clara, CA , you have various bus station options to start your journey from including San José, Cahill Street (Diridon Station) . When arriving in San Diego, CA , you can end your journey in bus stations like San Diego, Congress Street (Old Town Park), CA, La Jolla, UCSD Health La Jolla Station, CA, San Diego, San Ysidro Transit Center, San Diego, West Harbor Drive (The Headquarters at Seaport District), CA .Passengers board the bus most frequently from San José, Cahill Street (Diridon Station), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at San Diego, Congress Street (Old Town Park), CA, located 5 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Santa Clara, CA and San Diego, CA including taking a bus, train, and flight.
No, the bus from Santa Clara, CA to San Diego, CA has no accessibility options.
No, there are no bathrooms on board the bus from Santa Clara, CA to San Diego, CA.
No, bikes are not allowed on board the bus from Santa Clara, CA to San Diego, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Santa Clara, CA to San Diego, CA.
No, luggage for the bus from Santa Clara, CA to San Diego, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Santa Clara, CA to San Diego, CA.
Unfortunately, pets are not allowed on the bus from Santa Clara, CA to San Diego, CA.
No, there are no USB plugs on board the bus from Santa Clara, CA to San Diego, CA.
No, there is no WiFi on board the bus from Santa Clara, CA to San Diego, CA.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Santa Clara, CA to San Diego, CA

Most Santa Clara, CA to San Diego, CA buses use the San José, Cahill Street (Diridon Station) to San Diego, Congress Street (Old Town Park) station pair, with some services arriving at San Diego, West Harbor Drive (The Headquarters at Seaport District). Use this guide to compare Santa Clara, CA and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Santa Clara
Arrival bus stations in San Diego

Which San Diego, CA station do buses from Santa Clara, CA arrive at?

Buses from Santa Clara, CA to San Diego, CA most often arrive at San Diego, Congress Street (Old Town Park). Some services arrive at La Jolla, UCSD Health La Jolla Station, so check your ticket before travel to confirm your San Diego, CA arrival station.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre

San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 20m · €1
83 · 26m · €5
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min

San Diego, Congress Street (Old Town Park) bus station facilities and services

San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).

Tickets and information

Ticket office support is available at San Diego, Congress Street (Old Town Park).

Parking, taxis and toilets

Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.

San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, San Ysidro Transit Center from San Diego city centre

San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 25m · €2
910 · 41m · €5
TramBlue · 41m · €14 · every ~14 min
Blue · 43m · €14 · every ~14 min

San Diego, San Ysidro Transit Center bus station facilities and services

San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food eateries located nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.

Tickets and information

Ticket office support is available at San Diego, San Ysidro Transit Center.

Parking, taxis and toilets

Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.

San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre

San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:

TRUE

San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services

San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options are in the area.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Tickets and information

Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Parking, taxis and toilets

Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.

Most popular bus connections from Santa Clara, CA

HomeBusesBuses in USABus tickets to San Diego, CASanta Clara, CA to San Diego, CA bus

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