- Must visit
San Diego Museum of Art
Major Balboa Park museum with works from Spanish old masters to modern art, plus strong regional and international exhibitions.
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Travel Information
Compare bus, train, and flight for Santa Clara, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Clara, CA to San Diego, CA among Omio's users. If you are prioritising price, take the train, with an average ticket price of zł749 For those with little time, consider booking a flight, which has an average total journey time of 7h 13m. Average ticket prices depend on the travel mode: a train costs an average of zł749, while a flight costs an average of zł3076.
Distance: 420 miles (676 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
zł1047 Average price | zł749 Average price Cheapest | zł3076 Average price | zł361 Average price (fuel + tolls) |
17h 13m Average total duration 16h 43m Onboard + 30m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 7h 13m Average total duration Fastest 5h 13m Onboard + 2h 0m Additional time* | 7h 57m Average total duration (door-to-door) |
 Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Santa Clara, CA to San Diego, CA is a train with an average price of zł749.
This is compared to other travel options from Santa Clara, CA to San Diego, CA:
A train is zł298 less than a bus for this route with tickets for a bus from Santa Clara, CA to San Diego, CA costing on average zł1047.
A train is zł2327 less than a flight for this route with tickets for a flight from Santa Clara, CA to San Diego, CA costing on average zł3076.
The fastest way to travel from Santa Clara, CA to San Diego, CA is by flight with an average journey time of 5h 13m.
Other travel options to San Diego, CA take longer:
Train takes on average 13h 39m.
Bus takes on average 16h 43m.
It's helpful to compare your options as there are 3 ways to travel between Santa Clara, CA and San Diego, CA including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Santa Clara, CA to San Diego, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Santa Clara, CA to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 01:00AM | Arrival Time 12:35PM | Duration 11h35 | Departure days Fri, Sat | Cheapest price zł430 |
Operator Amtrak | Departure Time 02:00AM | Arrival Time 01:35PM | Duration 11h35 | Departure days Thu | Cheapest price zł415 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 05:15AM | Duration 13h40 | Departure days Wed | Cheapest price zł377 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 06:15AM | Duration 12h50 | Departure days Mon | Cheapest price zł199 |
Compare prices and tickets Santa Clara, CA to San Diego, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Santa Clara, CA to San Diego, CA
USAUSA
Buses from Santa Clara, CA to San Diego, CA run on average 2 times per day, taking around 16h 43m. Cheap bus tickets for this journey start at zł1025 but you can travel from only zł692 by train.
The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 16h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from zł692
Distance 420 miles (676 km) |
Average bus duration 16h 43m |
Cheapest ticket price zł1025 |
Buses per day 2 |
Fastest bus 16h 25m |
First bus 12:05 AM |
Last bus 11:45 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from zł692
Complete guide to San Diego, CA
Things to do in San Diego, CA
Discover the best of San Diego, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego, CA trip today.
- Must visit
Museum of Contemporary Art San Diego
Acclaimed contemporary art museum in La Jolla featuring oceanfront settings, modern works, and rotating global exhibitions.
- Must visit
USS Midway Museum
Museum aboard a historic aircraft carrier with restored aircraft, naval exhibits, and immersive views of life at sea.
- Must visit
Balboa Park
Balboa Park is San Diego's grand cultural park, packed with gardens, architecture, museums, and walkable plazas worth lingering in.
- Must visit
Gaslamp Quarter
Historic Gaslamp Quarter offers Victorian-era streets, nightlife energy, and preserved downtown architecture for an atmospheric walk.
- Must visit
La Jolla Cove
Dramatic seaside cliffs and walking paths in La Jolla, famous for waves, sea lions, and sweeping Pacific views.
Fish Taco
A San Diego staple: grilled fish in a soft tortilla with cabbage, crema, and salsa. Popularized by Baja influence and coastal seafood culture.
California Burrito
French fries, carne asada, cheese, guacamole, and crema wrapped in a flour tortilla. A late-night local favorite born in San Diego taquerias.
- Gluten-free
Sea Urchin (Uni)
Fresh local sea urchin served raw, prized for its rich, buttery taste. It reflects San Diego's access to Pacific seafood and sushi culture.
Sushi Ota
Celebrated sushi restaurant specializing in omakase and pristine seafood, including uni. Intimate, polished, and highly respected by locals.
Mitch's Seafood
Iconic casual seafood counter known for fish tacos, smoked fish, and harbor views. A classic stop for San Diego's Baja-inspired seafood style.
Juniper and Ivy
Refined fine-dining restaurant showcasing local seafood and seasonal California ingredients. Elegant room with one of the city's strongest reputations.
US Dollar ($)
San Diego is pricey for US travel, with higher hotel rates, dining, and parking than many cities, though casual food and buses stay manageable.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a mid-range meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $4-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis or rideshares, and $1-2 for coffee drinks or small cafe orders.
FAQs: Bus from Santa Clara, CA to San Diego, CA
Find answers to the most common questions about traveling from Santa Clara, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Santa Clara, CA to San Diego, CA can start from as little as zł1025 when you book in advance. The average bus ticket price for Santa Clara, CA to San Diego, CA is zł1047 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Santa Clara, CA to San Diego, CA is 16h 25m to travel the 420 miles (676 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Santa Clara, CA to San Diego, CA leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Santa Clara, CA to San Diego, CA leaves at 11:45 PM.
When departing from Santa Clara, CA , you have various bus station options to start your journey from including San José, Cahill Street (Diridon Station), San Jose, CA . When arriving in San Diego, CA , you can end your journey in bus stations like San Diego, Congress Street (Old Town Park), CA, San Diego, San Ysidro Transit Center, San Diego, CA, La Jolla, UCSD Health La Jolla Station, CA, San Diego, West Harbor Drive (The Headquarters at Seaport District), CA, San Diego, Rail Ct / E San Ysidro Blvd (McDonald`s), CA .Passengers board the bus most frequently from San José, Cahill Street (Diridon Station), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at San Diego, Congress Street (Old Town Park), CA, located 5 away from the city centre.
A trip to San Diego, CA from Santa Clara, CA is worth doing but not as a day trip with a journey time of 16h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Santa Clara, CA to San Diego, CA is November.
It's helpful to compare your options as there are 3 ways to travel between Santa Clara, CA and San Diego, CA including taking a bus, train, and flight.
No, the bus from Santa Clara, CA to San Diego, CA has no accessibility options.
No, there are no bathrooms on board the bus from Santa Clara, CA to San Diego, CA.
Some of the most interesting sights to explore in San Diego, CA are:
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
The best things to do in San Diego, CA include:
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
No, bikes are not allowed on board the bus from Santa Clara, CA to San Diego, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Santa Clara, CA to San Diego, CA.
No, luggage for the bus from Santa Clara, CA to San Diego, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Santa Clara, CA to San Diego, CA.
Unfortunately, pets are not allowed on the bus from Santa Clara, CA to San Diego, CA.
No, there are no USB plugs on board the bus from Santa Clara, CA to San Diego, CA.
No, there is no WiFi on board the bus from Santa Clara, CA to San Diego, CA.
Since neither Santa Clara, CA nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Santa Clara, CA to San Diego, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Santa Clara, CA to San Diego, CA
Most Santa Clara, CA to San Diego, CA buses use the San José, Cahill Street (Diridon Station) to San Diego, Congress Street (Old Town Park) station pair, with some services arriving at San Diego, San Ysidro Transit Center. Use this guide to compare Santa Clara, CA and San Diego, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Santa Clara
Arrival bus stations in San Diego
Which San Diego, CA station do buses from Santa Clara, CA arrive at?
Buses from Santa Clara, CA to San Diego, CA most often arrive at San Diego, Congress Street (Old Town Park). Some services arrive at San Diego, San Ysidro Transit Center, so check your ticket before travel to confirm your San Diego, CA arrival station.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USA
City-centre transport
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 20m · zł5
83 · 26m · zł23
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USA
City-centre transport
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
BusFlixBus 2017 · 25m · zł9
910 · 41m · zł23
TramBlue · 41m · zł65 · every ~14 min
Blue · 43m · zł65 · every ~14 min
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
San DiegoSan Diego, CA, USA
City-centre transport
Getting to San Diego from San Diego city centre
Bus215, 225, 235, 910 · 5m · zł23 · every ~22 min
TramBlue, Orange · 2m · every ~15 min
San Diego bus station facilities and services
San Diego has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: There are fast food outlets nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego. ATMs are available at San Diego.
Tickets and information
Ticket office support is available at San Diego.
Parking, taxis and toilets
Available at San Diego: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego: Station is accessible for individuals with disabilities.
Most popular bus connections from Santa Clara, CA
More options for your journey from Santa Clara, CA to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and Santa Clara, CA
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