The cheapest and fastest buses from Santa Clara, CA to San Diego, CA
Cheapest price
$120
Average price
$130
Fastest journey
14 h 37 m
Average duration
14 h 49 m
Buses per day
3
Distance
676 km
The best way to find a cheap bus ticket from Santa Clara, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Clara, CA to San Diego, CA will cost around $130 if you buy it on the day, but the cheapest tickets can be found for only $120.
Of the 3 buses that leave Santa Clara, CA for San Diego, CA on Thu, Nov 27, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 27 the direct buses cover the 676 km distance in an average of 14 h 49 m but if you time it right, some buses will get you there in just 14 h 37 m .
On Thu, Nov 27 the slowest buses will take 15 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, and flight for Santa Clara, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Clara, CA to San Diego, CA among Omio's users. If you are prioritising price take the train with prices starting from €76. For those with little time consider booking a flight which can get you there in 5h 43m. The ticket price range depends on the travel mode: a train costs an average of €76, and a flight costs an average of €70.
Distance: 420 miles (676 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€106 Average price | €98 Average price Cheapest | €156 Average price |
15h 26m Average total duration 14h 56m Onboard + 30m Additional time* | 12h 52m Average total duration 12h 22m Onboard + 30m Additional time* | 8h 43m Average total duration Fastest 5h 43m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Clara, CA to San Diego, CA bus times
The table below shows live departures for Santa Clara, CA to San Diego, CA buses for today, Wednesday, November 26. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:38 PM Santa Clara, CA | 14h47 | 12:25 PM San Diego, CA | 0 transfersDirect | |
![]() | 9:48 PM Santa Clara, CA | 14h37 | 12:25 PM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Clara, CA to San Diego, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Journey information
Overview: Bus from Santa Clara, CA to San Diego, CA
Buses from Santa Clara, CA to San Diego, CA run on average 7 times per day, taking around 14h 56m. Cheap bus tickets for this journey start at $82 (€66) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 13h 30m.
Distance 420 miles (676 km) |
Average bus duration 14h 56m |
Cheapest ticket price $82 (€66) |
Buses per day 7 |
Direct buses 1 |
Fastest bus 13h 30m |
First bus 00:05 |
Last bus 23:45 |
FAQs: Bus from Santa Clara, CA to San Diego, CA
Find answers to the most common questions about traveling from Santa Clara, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- Enjoy a harbor cruise for stunning views of the skyline and naval ships
- Hike the scenic trails at Torrey Pines State Natural Reserve
- Visit the Birch Aquarium to learn about marine life and ocean conservation
- Experience the thrill of a whale watching tour off the coast.
To find the cheapest bus tickets for your trip from Santa Clara, CA to San Diego, CA, follow these tips:
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Popular bus stations from Santa Clara, CA to San Diego, CA
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