The cheapest and fastest buses from Santa Clara, CA to San Diego, CA
Cheapest price
$114
Average price
$119
Fastest journey
11 h 35 m
Average duration
13 h 6 m
Buses per day
2
Distance
676 km
The best way to find a cheap bus ticket from Santa Clara, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Clara, CA to San Diego, CA will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $114.
Of the 2 buses that leave Santa Clara, CA for San Diego, CA on Thu, Apr 16, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 16 the direct buses cover the 676 km distance in an average of 13 h 6 m but if you time it right, some buses will get you there in just 11 h 35 m .
On Thu, Apr 16 the slowest buses will take 14 h 37 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2:00 AM11h35Santa Clara, CA1:35 PMSan Diego, CA$1141One-way0 transfers
10:48 PM14h37Santa Clara, CA1:25 PMSan Diego, CA$1251One-way0 transfers
2:00 AM11h35Santa Clara, CA1:35 PMSan Diego, CA$1141One-way0 transfers
10:48 PM14h37Santa Clara, CA1:25 PMSan Diego, CA$1251One-way0 transfers
Travel Information
Compare bus, train, and flight for Santa Clara, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Clara, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $54. For those with little time consider booking a flight which can get you there in 2h 1m. The ticket price range depends on the travel mode: a bus costs an average of $54, and a flight costs an average of $71.
Distance: 420 miles (676 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$118 Average price Cheapest | $132 Average price | $212 Average price |
14h 27m Average total duration 13h 57m Onboard + 30m Additional time* | 12h 52m Average total duration 12h 22m Onboard + 30m Additional time* | 5h 1m Average total duration Fastest 2h 1m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Clara, CA to San Diego, CA bus times
The table below shows live departures for Santa Clara, CA to San Diego, CA buses for today, Tuesday, April 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:48 PM Santa Clara, CA | 14h37 | 1:25 PM San Diego, CA | 0 transfersDirect | |
| Wednesday, April 15 | |||||
![]() | 2:00 AM Santa Clara, CA | 11h35 | 1:35 PM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Clara, CA to San Diego, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 15
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Journey information
Overview: Bus from Santa Clara, CA to San Diego, CA
Buses from Santa Clara, CA to San Diego, CA run on average 5 times per day, taking around 13h 57m. Cheap bus tickets for this journey start at $54 (€43) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 11h 35m.
Distance 420 miles (676 km) |
Average bus duration 13h 57m |
Cheapest ticket price $54 (€43) |
Buses per day 5 |
Direct buses 1 |
Fastest bus 11h 35m |
First bus 12:05 AM |
Last bus 11:45 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Best time to book 7 days |
FAQs: Bus from Santa Clara, CA to San Diego, CA
Find answers to the most common questions about traveling from Santa Clara, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
popular bus stations
Popular bus stations from Santa Clara, CA to San Diego, CA
Most popular bus connections from Santa Clara, CA
More options for your journey from Santa Clara, CA to San Diego, CA
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