- Recommended
Jack and Shanaz Langson Institute and Museum of California Art
Orange County’s leading contemporary art museum, presenting rotating exhibitions and acclaimed modern artists near UC Irvine.
Omio recommends booking the bus as it is the most popular option from Denver, CO to Irvine, CA among Omio's users.
Distance: 824 miles (1327 km)
Most popular Bus | Driving |
|---|---|
$211 Average price (fuel + tolls) | |
14h 50m Average total duration (door-to-door) | |
Direct Options | Direct Options |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 11:05AM | Arrival Time 05:42AM | Duration 42h37 | Departure days Tue, Fri, Sat, Sun | Cheapest price $263 |
Operator Greyhound | Departure Time 05:05PM | Arrival Time 06:30PM | Duration 25h25 | Departure days Wed, Thu | Cheapest price $219 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Denver, CO to Irvine, CA and enjoy the approximately 824 miles (1327 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 08:46, the last at 21:40.
Distance 824 miles (1327 km) |
First bus 8:46 AM |
Last bus 9:40 PM |
Cheapest Month Jan |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Irvine, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Irvine, CA trip today.
Orange County’s leading contemporary art museum, presenting rotating exhibitions and acclaimed modern artists near UC Irvine.
University art museum featuring exhibitions of contemporary and historical works, with thought-provoking programs and free admission.
Historic farm site with interpretive exhibits, original structures, and programs that bring Orange County’s agricultural past to life.
Major civic park with trails, sports areas, art spaces, and the iconic balloon, popular with both visitors and locals.
Lakeside shopping and entertainment district with landscaped plazas and a lively pedestrian setting day and night.
Circular park at the heart of UC Irvine with mature trees and paths, ideal for walking, picnics, and campus atmosphere.
Fish tacos are a Southern California staple: battered or grilled fish in corn tortillas with cabbage, crema, and salsa. They reflect the region’s Baja and coastal influence.
California rolls were popularized in Southern California sushi culture. Crab, avocado, and cucumber make them approachable and iconic to the region’s Japanese influence.
Avocado toast is a modern California café classic. Fresh avocado on artisan bread showcases the state’s produce culture and everyday brunch habits.
Established Japanese restaurant in Diamond Jamboree known for quality sushi, izakaya dishes, and a polished yet comfortable setting.
Well-known upscale-casual venue serving seasonal Californian cuisine. Stylish room and dependable service make it a strong fine dining option.
Highly regarded Taiwanese bakery café famous for sea salt coffee, breads, and desserts. Casual, busy, and representative of Irvine’s café culture.
Irvine is pricier than many US cities, with higher hotel and dining costs. Transit is limited, so visitors often need taxis or rental cars, raising daily spend.
Tip 18-20% at restaurants, 15-20% for taxis and rideshares, and $1-2 per drink or coffee is appreciated.
Find answers to the most common questions about traveling from Denver, CO to Irvine, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Irvine, CA, this guide helps you travel smarter and with confidence.

Most Denver, CO to Irvine, CA buses use the Denver, Union Station to Anaheim, Regional Transportation Intermodal Center (ARTIC) station pair. Use this guide to compare Denver, CO and Irvine, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need