Port Saint Lucie, FL to San Francisco, CA bus

Thu, Feb 05
+ Add return
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Costa Verde
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from Port Saint Lucie, FL to San Francisco, CA

Showing times and prices for Feb 06

Cheapest price

$331

Average price

$331

Fastest journey

3 d 17 h 55 m

Average duration

3 d 17 h 55 m

Buses per day

1

Distance

4075 km

Cheap tickets

The best way to find a cheap bus ticket from Port Saint Lucie, FL to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Port Saint Lucie, FL to San Francisco, CA will cost around $331 if you buy it on the day, but the cheapest tickets can be found for only $331.

Fast buses

Of the 1 buses that leave Port Saint Lucie, FL for San Francisco, CA on Fri, Feb 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Feb 06 the direct buses cover the 4075 km distance in an average of 3 d 17 h 55 m but if you time it right, some buses will get you there in just 3 d 17 h 55 m .

On Fri, Feb 06 the slowest buses will take 3 d 17 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
07:45PM89h55
Port Saint Lucie, FL
01:40PMSan Francisco, CA
$3311One-way
0 transfers

Travel Information

Compare bus and flight for Port Saint Lucie, FL to San Francisco, CA

Omio recommends booking the flight as it is the most popular option from Port Saint Lucie, FL to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €263. For those with little time consider booking a flight which can get you there in 10h 6m. The ticket price range depends on the travel mode: a bus costs an average of €263, and a flight costs an average of €352.

Distance: 2532 miles (4075 km)

Compare bus with

Bus
Most popular
Flight

€263

Average price

Cheapest

€352

Average price

90h 25m

Average total duration

89h 55m

Onboard

+

30m

Additional time*

13h 6m

Average total duration

Fastest

10h 6m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Port Saint Lucie, FL to San Francisco, CA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Feb 06
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Feb 07
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Feb 08
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Feb 09
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Feb 12

Journey information

Overview: Bus from Port Saint Lucie, FL to San Francisco, CA

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Buses from Port Saint Lucie, FL to San Francisco, CA run on average 6 times per day, taking around 89h 55m. Cheap bus tickets for this journey start at $331 (€263) if you book in advance.

The earliest bus runs at 19:45, the last at 19:45. The fastest bus covers the 2532 miles (4075 km) distance in 89h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
2532 miles (4075 km)
Average bus duration
89h 55m
Cheapest ticket price
$331 (€263)
Buses per day
6
Fastest bus
89h 55m
First bus
19:45
Last bus
19:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Port Saint Lucie, FL to San Francisco, CA

Find answers to the most common questions about traveling from Port Saint Lucie, FL to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Port Saint Lucie, FL to San Francisco, CA can start from as little as $331 (€263) when you book in advance. The average bus ticket price for Port Saint Lucie, FL to San Francisco, CA is $331 (€263) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Port Saint Lucie, FL to San Francisco, CA is 89h 55m to travel the 2532 miles (4075 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Port Saint Lucie, FL to San Francisco, CA leaves at 7:45 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Port Saint Lucie, FL to San Francisco, CA leaves at 7:45 PM.
A trip to San Francisco, CA from Port Saint Lucie, FL is worth doing but not as a day trip with a journey time of 89h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Port Saint Lucie, FL to San Francisco, CA is June.
It's helpful to compare your options as there are 2 ways to travel between Port Saint Lucie, FL and San Francisco, CA including taking a bus and flight.
No, the bus from Port Saint Lucie, FL to San Francisco, CA has no accessibility options.
No, there are no bathrooms on board the bus from Port Saint Lucie, FL to San Francisco, CA.
Some of the most interesting sights to explore in San Francisco, CA are:
  • Golden Gate Bridge, an iconic suspension bridge offering panoramic views of the San Francisco Bay
  • Alcatraz Island, a historic site featuring the infamous former prison and informative audio tours
  • Fisherman's Wharf, a bustling waterfront area known for seafood, shops, and sea lions
  • Golden Gate Park, a large urban park with gardens, museums, and recreational activities
  • Chinatown, the oldest and one of the largest Chinatowns in North America, offering vibrant culture and cuisine.
The best things to do in San Francisco, CA include:
  • Ride a cable car through the steep streets of San Francisco for a classic city experience
  • Explore the vibrant murals and street art in the Mission District
  • Visit the Exploratorium, an interactive science museum perfect for all ages
  • Take a scenic walk along the Embarcadero, offering views of the Bay Bridge and access to the Ferry Building Marketplace
  • Enjoy a wine tasting tour in nearby Napa Valley, a short drive from the city.
No, bikes are not allowed on board the bus from Port Saint Lucie, FL to San Francisco, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Port Saint Lucie, FL to San Francisco, CA.
No, luggage for the bus from Port Saint Lucie, FL to San Francisco, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Port Saint Lucie, FL to San Francisco, CA.
Unfortunately, pets are not allowed on the bus from Port Saint Lucie, FL to San Francisco, CA.
No, there are no USB plugs on board the bus from Port Saint Lucie, FL to San Francisco, CA.
No, there is no WiFi on board the bus from Port Saint Lucie, FL to San Francisco, CA.

popular bus stations

Popular bus stations from Port Saint Lucie, FL to San Francisco, CA

Port Saint Lucie
San Francisco
The major bus station for departures in Port Saint Lucie is Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot). Find all the information you need to know about services, amenities and connections at Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot) for your trip from Port Saint Lucie to San Francisco.
Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot)
information

More options for your journey from Port Saint Lucie, FL to San Francisco, CA

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