- Must visit
Cummer Museum of Art & Gardens
Major art museum on the St. Johns River with a strong permanent collection and historic formal gardens. One of Jacksonville’s best-known cultural attractions.
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The cheapest and fastest buses from Port Saint Lucie, FL to Jacksonville, FL
Showing times and prices for Jun 01
Cheapest price
$46
Average price
$67
Fastest journey
6 h 5 m
Average duration
6 h 10 m
Buses per day
2
Distance
361 km
Cheap tickets
The best way to find a cheap bus ticket from Port Saint Lucie, FL to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Port Saint Lucie, FL to Jacksonville, FL will cost around $67 if you buy it on the day, but the cheapest tickets can be found for only $46.
Fast buses
Of the 2 buses that leave Port Saint Lucie, FL for Jacksonville, FL on Mon, Jun 01, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 01 the direct buses cover the 361 km distance in an average of 6 h 10 m but if you time it right, some buses will get you there in just 6 h 5 m .
On Mon, Jun 01 the slowest buses will take 6 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
8:45 AM6h15Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot), FL3:00 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$461One-way0 transfers
FlixBus · FlixBus1:40 AM6h05Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot), FL7:45 AMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$871One-way1 transfer
- FlixBus · FlixBus1:40 AM6h05Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot), FL7:45 AMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$871One-way1 transfer
- 8:45 AM6h15Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot), FL3:00 PMJacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St$461One-way0 transfers
Travel Information
Compare bus, train, and flight for Port Saint Lucie, FL to Jacksonville, FL
Omio recommends booking the train as it is the most popular option from Port Saint Lucie, FL to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $41. For those with little time consider booking a bus which can get you there in 5h 43m. The ticket price range depends on the travel mode: a bus costs an average of $41, and a flight costs an average of $373.
Distance: 224 miles (361 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$62 Average price Cheapest | $79 Average price | $676 Average price | $48 Average price (fuel + tolls) |
6h 13m Average total duration Fastest 5h 43m Onboard + 30m Additional time* | 9h 8m Average total duration 8h 38m Onboard + 30m Additional time* | 17h 29m Average total duration 14h 29m Onboard + 3h 0m Additional time* | 3h 23m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Port Saint Lucie, FL to Jacksonville, FL is a bus with an average price of $62 (€50).
This is compared to other travel options from Port Saint Lucie, FL to Jacksonville, FL:
A bus is $17 (€14) less than a train for this route with tickets for a train from Port Saint Lucie, FL to Jacksonville, FL costing on average $79 (€64).
A bus is $614 (€494) less than a flight for this route with tickets for a flight from Port Saint Lucie, FL to Jacksonville, FL costing on average $676 (€544).
The fastest way to travel from Port Saint Lucie, FL to Jacksonville, FL is by bus with an average journey time of 5h 43m.
Other travel options to Jacksonville, FL take longer:
Train takes on average 8h 38m.
Flight takes on average 14h 29m.
It's helpful to compare your options as there are 3 ways to travel between Port Saint Lucie, FL and Jacksonville, FL including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Port Saint Lucie, FL to Jacksonville, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about -3h -20m sooner (5h 43m by bus vs 3h 23m by car) and save roughly $-13.78 (€-11.09) compared to fuel and tolls ($62 (€50) vs $48 (€39)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Port Saint Lucie, FL to Jacksonville, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:40AM | Arrival Time 08:50AM | Duration 7h10 | Departure days Mon, Tue | Cheapest price $69 |
Operator Jet Set Express | Departure Time 08:05AM | Arrival Time 03:45PM | Duration 7h40 | Departure days Sat | Cheapest price $72 |
Operator Greyhound | Departure Time 08:45AM | Arrival Time 03:00PM | Duration 6h15 | Departure days Mon, Tue | Cheapest price $43 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 07:00PM | Duration 6h05 | Departure days Wed, Thu, Sun | Cheapest price $47 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 08:00PM | Duration 6h05 | Departure days Thu, Fri | Cheapest price $52 |
Operator Greyhound | Departure Time 07:45PM | Arrival Time 11:45AM | Duration 16h00 | Departure days Wed | Cheapest price $100 |
Live departures
Port Saint Lucie, FL to Jacksonville, FL bus times
The table below shows live departures for Port Saint Lucie, FL to Jacksonville, FL buses for today, Sunday, May 31. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:55 PM Port Saint Lucie, FL | 6h05 | 7:00 PM Jacksonville, FL | 0 transfersDirect | |
| Monday, June 1 | |||||
| FlixBus · FlixBus | 1:40 AM Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot), FL | 6h05 | 7:45 AM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Port Saint Lucie, FL to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Port Saint Lucie, FL to Jacksonville, FL buses with Omio?
Greyhound as well as Jet Set Express or Area Regional Transit St Lucie offer buses services from Port Saint Lucie, FL to Jacksonville, FL.
Omio is an official ticket reseller for all your travel options from Port Saint Lucie, FL to Jacksonville, FL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Jet Set Express or Area Regional Transit St Lucie to find the best option for your trip from Port Saint Lucie, FL to Jacksonville, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Port Saint Lucie, FL to Jacksonville, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Port Saint Lucie, FL to Jacksonville, FL.
Journey information
Overview: Bus from Port Saint Lucie, FL to Jacksonville, FL
USAUSA
Buses from Port Saint Lucie, FL to Jacksonville, FL run on average 2 times per day, taking around 5h 43m. Cheap bus tickets for this journey start at $41 (€33) if you book in advance.
There are 1 buses per day. The earliest bus runs at 01:40, the last at 21:10. The fastest bus covers the 224 miles (361 km) distance in 6h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 224 miles (361 km) |
Average bus duration 5h 43m |
Cheapest ticket price $41 (€33) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 6h 5m |
First bus 1:40 AM |
Last bus 9:10 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, Jet Set Express, Area Regional Transit St Lucie from Port Saint Lucie, FL to Jacksonville, FLYou can travel by bus between Port Saint Lucie, FL to Jacksonville, FL with Greyhound, Jet Set Express, Area Regional Transit St Lucie for as low as $41 (€33). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
6h 5m
Cheapest Price
$41 (€33)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Jet Set Express
Luggage & cancellation policy
Average Duration
7h 40m
Cheapest Price
$72 (€58)
Jet Set Express frequency
1 a day
Area Regional Transit St Lucie
Luggage & cancellation policy
Average Duration
6h 56m
Area Regional Transit St Lucie frequency
1 a day
Complete guide to Jacksonville
Things to do in Jacksonville
Discover the best of Jacksonville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jacksonville trip today.
- Must visit
MOSH
The Museum of Science & History features science, regional history, and family-friendly exhibits on the Southbank. It is one of Jacksonville’s most popular museums.
- Recommended
Museum of Contemporary Art Jacksonville
Downtown contemporary art museum presenting rotating exhibitions, modern works, and public programs. A top stop for current visual culture in the city.
- Must visit
Riverwalk
Scenic pedestrian route along both sides of the St. Johns River with skyline views, bridges, and easy access to downtown sights. One of the city’s best walks.
- Must visit
Riverside Avondale
Historic neighborhood district known for walkable streets, boutiques, parks, and preserved architecture. Very popular with locals for casual exploring and photos.
- Must visit
Jacksonville Beach
The city’s best-known beach area with a broad sandy shoreline, fishing pier area, and active promenade atmosphere. Strong social media appeal, especially at sunrise.
- Gluten-free
Mayport Shrimp
Wild-caught shrimp from nearby Mayport, commonly served fried, grilled, blackened, or in baskets and tacos. It is one of the area’s best-known local seafood specialties.
Fried Shrimp Basket
A classic Jacksonville beach-area meal featuring local shrimp, fries, and slaw. It is especially associated with casual seafood spots near the coast.
- Gluten-free
Low Country Boil
A regional coastal feast of shrimp, sausage, corn, and potatoes boiled with seasoning. Popular in Northeast Florida and commonly shared at casual gatherings.
Maple Street Biscuit Company
A well-known local-born breakfast and brunch spot famous for Southern biscuit sandwiches, gravy, and a relaxed neighborhood feel.
The Bearded Pig
A popular Jacksonville barbecue restaurant serving smoked meats, hearty sides, and craft beer in a lively, casual setting.
Cowford Chophouse
An upscale downtown steakhouse in a historic building, known for steaks, seafood, rooftop dining, and polished service.
United States Dollar
Generally moderate for U.S. city travel. Meals and transport are reasonable, while beachfront stays cost more.
Average meal costs
- Budget
- USD 10-15 for fast food or a casual lunch.
- Mid-range
- USD 20-40 per person at a standard restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 15-20% at restaurants. Bartenders: USD 1-2 per drink. Taxis and rideshares: 10-15% or round up. Hotel staff: USD 2-5 for bags; USD 2-5 nightly for housekeeping.
FAQs: Bus from Port Saint Lucie, FL to Jacksonville, FL
Find answers to the most common questions about traveling from Port Saint Lucie, FL to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Port Saint Lucie, FL to Jacksonville, FL can start from as little as $41 (€33) when you book in advance. The average bus ticket price for Port Saint Lucie, FL to Jacksonville, FL is $62 (€50) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Port Saint Lucie, FL to Jacksonville, FL is 6h 5m to travel the 224 miles (361 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Port Saint Lucie, FL to Jacksonville, FL leaves at 1:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Port Saint Lucie, FL to Jacksonville, FL leaves at 9:10 PM.
Yes, there are 1 direct buses a day from Port Saint Lucie, FL to Jacksonville, FL with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Port Saint Lucie, FL to Jacksonville, FL, you can count on Greyhound, Jet Set Express, Area Regional Transit St Lucie for the best way to get you to Jacksonville, FL. You can also check all possible bus companies who offer a service between Port Saint Lucie, FL and Jacksonville, FL and compare the amenities they offer before buying a bus ticket.
A trip to Jacksonville, FL from Port Saint Lucie, FL is worth doing but not as a day trip with a journey time of 6h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Port Saint Lucie, FL to Jacksonville, FL is July.
It's helpful to compare your options as there are 3 ways to travel between Port Saint Lucie, FL and Jacksonville, FL including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Port Saint Lucie, FL to Jacksonville, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Port Saint Lucie, FL to Jacksonville, FL for bus company Greyhound.
Whether you can cancel your bus ticket from Port Saint Lucie, FL to Jacksonville, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Port Saint Lucie, FL to Jacksonville, FL.
Yes, the following luggage options are included when booking a bus ticket from Port Saint Lucie, FL to Jacksonville, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Port Saint Lucie, FL to Jacksonville, FL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Port Saint Lucie, FL to Jacksonville, FL.
You can reserve your seat on the bus from Port Saint Lucie, FL to Jacksonville, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Port Saint Lucie, FL to Jacksonville, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Port Saint Lucie, FL to Jacksonville, FL with the following bus company: Greyhound.
Since neither Port Saint Lucie, FL nor Jacksonville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Port Saint Lucie, FL to Jacksonville, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jacksonville, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots. Common scams include overcharging by unlicensed taxi or ride-share drivers and fake ticket sellers near attractions. Staying aware of surroundings, using reputable transportation services, and avoiding isolated areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Port Saint Lucie, FL to Jacksonville, FL
Port Saint Lucie
Jacksonville
The major bus station for departures in Port Saint Lucie is Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot). Find all the information you need to know about services, amenities and connections at Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot) for your trip from Port Saint Lucie to Jacksonville.
Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot)
information
The major bus station for arrivals in Jacksonville is Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St. Find all the information you need to know about services, amenities and connections at Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St for your trip to Jacksonville from Port Saint Lucie.
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St
information
More options for your journey from Port Saint Lucie, FL to Jacksonville, FL
Here are some other resources that might have the information you need
Most popular buses to and from Jacksonville, FL and Port Saint Lucie, FL
Most popular bus connections to Jacksonville, FL
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