Port Saint Lucie, FL to Jacksonville, FL bus with Greyhound

Sun, Mar 01
+ Add return
Greyhound
Jet Set Express
FlixBus
Alsa
Costa Verde
1,000+ travel companies
Greyhound
Jet Set Express
FlixBus
Alsa
Costa Verde
1,000+ travel companies
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The cheapest and fastest buses from Port Saint Lucie, FL to Jacksonville, FL

Showing times and prices for Mar 02

Cheapest price

$53

Average price

$53

Fastest journey

6 h 5 m

Average duration

6 h 5 m

Buses per day

1

Distance

361 km

Cheap tickets

The best way to find a cheap bus ticket from Port Saint Lucie, FL to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Port Saint Lucie, FL to Jacksonville, FL will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $53.

Fast buses

Of the 1 buses that leave Port Saint Lucie, FL for Jacksonville, FL on Mon, Mar 02, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Mar 02 the direct buses cover the 361 km distance in an average of 6 h 5 m but if you time it right, some buses will get you there in just 6 h 5 m .

On Mon, Mar 02 the slowest buses will take 6 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
01:55PM6h05
Port Saint Lucie, FL
08:00PMJacksonville, FL
$531One-way
0 transfers

Travel Information

Compare bus, train, and flight for Port Saint Lucie, FL to Jacksonville, FL

Omio recommends booking the bus as it is the most popular option from Port Saint Lucie, FL to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $47. For those with little time consider booking a bus which can get you there in 5h 43m. The ticket price range depends on the travel mode: a bus costs an average of $47, and a flight costs an average of $337.

Distance: 224 miles (361 km)

Compare bus with

Most popular
Bus
Train
Flight

$64

Average price

Cheapest

$85

Average price

$580

Average price

6h 13m

Average total duration

Fastest

5h 43m

Onboard

+

30m

Additional time*

9h 5m

Average total duration

8h 35m

Onboard

+

30m

Additional time*

16h 16m

Average total duration

13h 16m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Port Saint Lucie, FL to Jacksonville, FL bus times

The table below shows live departures for Port Saint Lucie, FL to Jacksonville, FL buses for tomorrow, Monday, March 2. You can also manually refresh the results below to see updated bus journeys.

Last updated at 2:56 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound1:55 PM Port Saint Lucie, FL
6h05
8:00 PM Jacksonville, FL0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Port Saint Lucie, FL to Jacksonville, FL by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Mar 02
Tue
Mar 03
Wed
Mar 04
Thu
Mar 05
Fri
Mar 06
Sat
Mar 07
Sun
Mar 08

Why should you book Port Saint Lucie, FL to Jacksonville, FL buses with Omio?

Greyhound as well as Jet Set Express offer buses services from Port Saint Lucie, FL to Jacksonville, FL.
Omio is an official ticket reseller for all your travel options from Port Saint Lucie, FL to Jacksonville, FL.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Jet Set Express to find the best option for your trip from Port Saint Lucie, FL to Jacksonville, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Port Saint Lucie, FL to Jacksonville, FL.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Port Saint Lucie, FL to Jacksonville, FL.

Journey information

Overview: Bus from Port Saint Lucie, FL to Jacksonville, FL

USAUSA
USAUSA
Icon of bus

Buses from Port Saint Lucie, FL to Jacksonville, FL run on average 2 times per day, taking around 5h 43m. Cheap bus tickets for this journey start at $47 (€38) if you book in advance.

There are 1 buses per day. The earliest bus runs at 01:40, the last at 21:10. The fastest bus covers the 224 miles (361 km) distance in 6h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
224 miles (361 km)
Average bus duration
5h 43m
Cheapest ticket price
$47 (€38)
Buses per day
2
Direct buses
1
Fastest bus
6h 5m
First bus
01:40
Last bus
21:10
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, Jet Set Express from Port Saint Lucie, FL to Jacksonville, FLYou can travel by bus between Port Saint Lucie, FL to Jacksonville, FL with Greyhound, Jet Set Express for as low as $47 (€38). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
6h 5m
Cheapest Price
$47 (€38)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Jet Set Express

Luggage & cancellation policy
Average Duration
7h 40m
Cheapest Price
$146 (€116)
Jet Set Express frequency
1 a day

FAQs: Bus from Port Saint Lucie, FL to Jacksonville, FL

Find answers to the most common questions about traveling from Port Saint Lucie, FL to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Port Saint Lucie, FL to Jacksonville, FL can start from as little as $47 (€38) when you book in advance. The average bus ticket price for Port Saint Lucie, FL to Jacksonville, FL is $64 (€51) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Port Saint Lucie, FL to Jacksonville, FL is 6h 5m to travel the 224 miles (361 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Port Saint Lucie, FL to Jacksonville, FL leaves at 1:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Port Saint Lucie, FL to Jacksonville, FL leaves at 9:10 PM.
Yes, there are 1 direct buses a day from Port Saint Lucie, FL to Jacksonville, FL with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Port Saint Lucie, FL to Jacksonville, FL, you can count on Greyhound, Jet Set Express for the best way to get you to Jacksonville, FL. You can also check all possible bus companies who offer a service between Port Saint Lucie, FL and Jacksonville, FL and compare the amenities they offer before buying a bus ticket.
A trip to Jacksonville, FL from Port Saint Lucie, FL is worth doing but not as a day trip with a journey time of 6h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Port Saint Lucie, FL to Jacksonville, FL is July.
It's helpful to compare your options as there are 3 ways to travel between Port Saint Lucie, FL and Jacksonville, FL including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Port Saint Lucie, FL to Jacksonville, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Port Saint Lucie, FL to Jacksonville, FL for bus company Greyhound.
Whether you can cancel your bus ticket from Port Saint Lucie, FL to Jacksonville, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Port Saint Lucie, FL to Jacksonville, FL.
Yes, the following luggage options are included when booking a bus ticket from Port Saint Lucie, FL to Jacksonville, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Port Saint Lucie, FL to Jacksonville, FL:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Port Saint Lucie, FL to Jacksonville, FL.
You can reserve your seat on the bus from Port Saint Lucie, FL to Jacksonville, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Port Saint Lucie, FL to Jacksonville, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Port Saint Lucie, FL to Jacksonville, FL with the following bus company: Greyhound.

popular bus stations

Popular bus stations from Port Saint Lucie, FL to Jacksonville, FL

Port Saint Lucie
Jacksonville
The major bus station for departures in Port Saint Lucie is Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot). Find all the information you need to know about services, amenities and connections at Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot) for your trip from Port Saint Lucie to Jacksonville.
Port St Lucie, SW Gatlin Blvd (Bus Transfer Station Park & Ride Lot)
information

More options for your journey from Port Saint Lucie, FL to Jacksonville, FL

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