- Must visit
The Charles Hosmer Morse Museum of American Art
Celebrated museum in nearby Winter Park famous for the world’s most comprehensive collection of works by Louis Comfort Tiffany.
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The cheapest and fastest buses from Panama City, FL to Orlando, FL
Showing times and prices for Jun 15
Cheapest price
$102
Average price
$104
Fastest journey
8 h
Average duration
9 h
Buses per day
3
Distance
452 km
Cheap tickets
The best way to find a cheap bus ticket from Panama City, FL to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Panama City, FL to Orlando, FL will cost around $104 if you buy it on the day, but the cheapest tickets can be found for only $102.
Fast buses
It's difficult to get from Panama City, FL to Orlando, FL without transferring at least once.
+
FlixBus12:50 PM10h09Panama City Beach, Back Beach Rd (Shell Gas Station), FL11:59 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1021One-way1 transfer- FlixBus+7:30 AM8h50Panama City Beach, Back Beach Rd (Shell Gas Station), FL5:20 PMOrlando, The Florida Mall, FL$1051One-way1 transfer
- FlixBus+7:30 AM8h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL4:30 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1051One-way1 transfer
- FlixBus+7:30 AM8h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL4:30 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1051One-way1 transfer
- FlixBus+7:30 AM8h50Panama City Beach, Back Beach Rd (Shell Gas Station), FL5:20 PMOrlando, The Florida Mall, FL$1051One-way1 transfer
- +FlixBus12:50 PM10h09Panama City Beach, Back Beach Rd (Shell Gas Station), FL11:59 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$1021One-way1 transfer
Travel Information
Compare bus and flight for Panama City, FL to Orlando, FL
Omio recommends booking the bus as it is the most popular option from Panama City, FL to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a bus which can get you there in 9h 20m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a flight costs an average of $378.
Distance: 280 miles (452 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$104 Average price Cheapest | $559 Average price | $69 Average price (fuel + tolls) |
9h 50m Average total duration Fastest 9h 20m Onboard + 30m Additional time* | 13h 50m Average total duration 10h 50m Onboard + 3h 0m Additional time* | 5h 37m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Panama City, FL to Orlando, FL is a bus with an average price of $104 (€84).
This is compared to other travel options from Panama City, FL to Orlando, FL:
A bus is $455 (€369) less than a flight for this route with tickets for a flight from Panama City, FL to Orlando, FL costing on average $559 (€454).
The fastest way to travel from Panama City, FL to Orlando, FL is by bus with an average journey time of 9h 20m.
Other travel options to Orlando, FL take longer:
Flight takes on average 10h 50m.
It's helpful to compare your options as there are 2 ways to travel between Panama City, FL and Orlando, FL including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Panama City, FL to Orlando, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Panama City, FL to Orlando, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:30AM | Arrival Time 09:15PM | Duration 12h45 | Departure days Wed | Cheapest price $97 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:20PM | Duration 8h50 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $86 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 08:30PM | Duration 8h00 | Departure days Sat | Cheapest price $68 |
Operator Greyhound | Departure Time 12:50PM | Arrival Time 02:35AM | Duration 12h45 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $85 |
Live departures
Panama City, FL to Orlando, FL bus times
The table below shows live departures for Panama City, FL to Orlando, FL buses for today, Sunday, June 14. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 7:30 AM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 8h50 | 5:20 PM Orlando, The Florida Mall, FL | 1 transfer | |
| FlixBus+ | 7:30 AM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 8h00 | 4:30 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
| +FlixBus | 12:50 PM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 10h09 | 11:59 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Panama City, FL to Orlando, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Panama City, FL to Orlando, FL buses with Omio?
Greyhound operates all buses services from Panama City, FL to Orlando, FL.
Omio is an official ticket reseller for all your travel options from Panama City, FL to Orlando, FL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Panama City, FL to Orlando, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Panama City, FL to Orlando, FL.
Journey information
Overview: Bus from Panama City, FL to Orlando, FL
USAUSA
Buses from Panama City, FL to Orlando, FL run on average 2 times per day, taking around 9h 20m. Cheap bus tickets for this journey start at $68 (€56) if you book in advance.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 280 miles (452 km) distance in 8h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 280 miles (452 km) |
Average bus duration 9h 20m |
Cheapest ticket price $68 (€56) |
Buses per day 2 |
Fastest bus 8h 0m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jan |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Panama City, FL to Orlando, FLYou can travel by bus between Panama City, FL to Orlando, FL with Greyhound for as low as $68 (€56). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 9m
Cheapest Price
$96 (€78)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Orlando
Things to do in Orlando
Discover the best of Orlando — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando trip today.
- Recommended
Orlando Museum of Art
Established art museum in Loch Haven Park with American art, African art, and rotating exhibitions; a leading cultural stop in the city.
- Recommended
Orange County Regional History Center
Well-regarded history museum in a restored courthouse covering Central Florida history, tourism, citrus, aviation, and local communities.
- Must visit
Lake Eola Park
Downtown Orlando’s most famous urban park, popular for skyline views, the lake loop, swan boats, events, and easy walking.
- Must visit
International Drive
Orlando’s best-known tourist corridor, lined with attractions, entertainment complexes, and highly photographed nightlife spots.
- Must visit
Winter Park Park Avenue
Charming, walkable main street area just north of Orlando, loved for its brick streets, boutique atmosphere, and polished local feel.
Cuban Sandwich
A pressed sandwich with roast pork, ham, Swiss cheese, pickles, and mustard on Cuban bread. It is a Central Florida staple shaped by the region’s Cuban influences.
Gator Bites
Fried alligator tail pieces, usually served with a dipping sauce. This is a classic Florida novelty dish tied to the state’s wetlands and Southern cooking traditions.
Florida Grouper Sandwich
A sandwich made with local grouper, often grilled, blackened, or fried. It is one of the most recognizable seafood dishes in Central Florida.
Victoria & Albert's
Orlando’s flagship fine-dining destination at Walt Disney World, known for tasting menus, polished service, and special-occasion dining.
Se7en Bites
Beloved neighborhood bakery and diner famous for Southern comfort food, biscuits, and outstanding pies and cakes.
The Ravenous Pig
A well-known Winter Park gastropub near Orlando, celebrated for refined American cooking, strong charcuterie, and a lively upscale-casual atmosphere.
United States Dollar
Moderate overall. Theme parks and resort areas are pricey, but casual dining and chain hotels can be reasonable outside peak seasons.
Average meal costs
- Budget
- USD 10-18 for fast food or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60+ per person at upscale restaurants.
- Coffee
- USD 3-6 for coffee or a latte.
Tipping culture
Tip 18-20% at restaurants if service is not included. Tip bartenders USD 1-2 per drink, taxis and rideshares 10-15%, hotel staff USD 1-5, and round up for cafes if desired.
FAQs: Bus from Panama City, FL to Orlando, FL
Find answers to the most common questions about traveling from Panama City, FL to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Panama City, FL to Orlando, FL can start from as little as $68 (€56) when you book in advance. The average bus ticket price for Panama City, FL to Orlando, FL is $104 (€84) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Panama City, FL to Orlando, FL is 8h 0m to travel the 280 miles (452 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Panama City, FL to Orlando, FL leaves at 4:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Panama City, FL to Orlando, FL leaves at 11:40 PM.
There are 2 buses a day from Panama City, FL to Orlando, FL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Panama City, FL to Orlando, FL, you can count on Greyhound for the best way to get you to Orlando, FL. You can also check all possible bus companies who offer a service between Panama City, FL and Orlando, FL and compare the amenities they offer before buying a bus ticket.
A trip to Orlando, FL from Panama City, FL is worth doing but not as a day trip with a journey time of 8h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Panama City, FL to Orlando, FL is January.
It's helpful to compare your options as there are 2 ways to travel between Panama City, FL and Orlando, FL including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Panama City, FL to Orlando, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Panama City, FL to Orlando, FL for bus company Greyhound.
Some of the most interesting sights to explore in Orlando, FL are:
- Walt Disney World Resort, a massive entertainment complex featuring theme parks, water parks, and resorts
- Universal Orlando Resort, a popular destination with thrilling rides, shows, and attractions based on movies and TV shows
- SeaWorld Orlando, a marine-themed park offering animal exhibits, shows, and rides
- Kennedy Space Center Visitor Complex, an educational attraction showcasing NASA's space exploration history and offering interactive exhibits
- Leu Gardens, a beautiful botanical garden with a variety of plant collections and scenic landscapes.
The best things to do in Orlando, FL include:
- ICON Park, a vibrant entertainment complex with dining, shopping, and the iconic Wheel for panoramic views
- Explore the vibrant nightlife and live entertainment at Church Street District
- Enjoy a day of shopping and dining at The Mall at Millenia
- Experience the natural beauty and wildlife at Wekiwa Springs State Park
- Visit the Orlando Science Center for interactive exhibits and planetarium shows.
Whether you can cancel your bus ticket from Panama City, FL to Orlando, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Panama City, FL to Orlando, FL.
Yes, the following luggage options are included when booking a bus ticket from Panama City, FL to Orlando, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Panama City, FL to Orlando, FL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Panama City, FL to Orlando, FL.
You can reserve your seat on the bus from Panama City, FL to Orlando, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Panama City, FL to Orlando, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Panama City, FL to Orlando, FL with the following bus company: Greyhound.
Since neither Panama City, FL nor Orlando, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Panama City, FL to Orlando, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Orlando, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like theme parks and popular tourist spots. Common scams include overpriced taxi rides, timeshare presentations that pressure visitors, and fake ticket sellers near major attractions. It's important to use authorized transportation services and purchase tickets from official vendors to avoid fraud. Additionally, travelers should stay aware of their surroundings and avoid poorly lit or isolated areas at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Panama City, FL to Orlando, FL
Panama City
Orlando
Orlando, N John Young Pkwy (Greyhound Bus Station)
information
Orlando, The Florida Mall
information
Most popular bus connections from Panama City, FL
More options for your journey from Panama City, FL to Orlando, FL
Here are some other resources that might have the information you need
Most popular buses to and from Orlando, FL and Panama City, FL
Most popular bus connections to Orlando, FL
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