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Orlando Science Center
Hands-on science center popular with families, offering interactive exhibits, live programming, and observatory experiences.
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The cheapest and fastest buses from Panama City, FL to Orlando, FL
Showing times and prices for Aug 04
Cheapest price
$91
Average price
$93
Fastest journey
8 h
Average duration
9 h 37 m
Buses per day
3
Distance
452 km
Cheap tickets
The best way to find a cheap bus ticket from Panama City, FL to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Panama City, FL to Orlando, FL will cost around $93 if you buy it on the day, but the cheapest tickets can be found for only $91.
Fast buses
It's difficult to get from Panama City, FL to Orlando, FL without transferring at least once.
+
FlixBus7:30 AM8h50Panama City Beach, Back Beach Rd (Shell Gas Station), FL5:20 PMOrlando, The Florida Mall, FL$911One-way1 transfer- +FlixBus7:30 AM8h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL4:30 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$931One-way1 transfer
- +FlixBus12:50 PM12h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL1:50 AMOrlando, N John Young Pkwy (Greyhound Bus Station)$941One-way1 transfer
- +FlixBus7:30 AM8h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL4:30 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$931One-way1 transfer
- +FlixBus7:30 AM8h50Panama City Beach, Back Beach Rd (Shell Gas Station), FL5:20 PMOrlando, The Florida Mall, FL$911One-way1 transfer
- +FlixBus12:50 PM12h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL1:50 AMOrlando, N John Young Pkwy (Greyhound Bus Station)$941One-way1 transfer
Journey information
Overview: Bus from Panama City, FL to Orlando, FL
USAUSA
Buses from Panama City, FL to Orlando, FL run on average 2 times per day, taking around 9h 20m. Cheap bus tickets for this journey start at $68 if you book in advance.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 280 miles (452 km) distance in 8h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 280 miles (452 km) |
Average bus duration 9h 20m |
Cheapest ticket price $68 |
Buses per day 2 |
Fastest bus 8h 0m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jan |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Panama City, FL to Orlando, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:30AM | Arrival Time 09:15PM | Duration 12h45 | Departure days Mon, Wed | Cheapest price $91 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:20PM | Duration 8h50 | Departure days Tue, Thu, Fri, Sat, Sun | Cheapest price $66 |
Operator Greyhound | Departure Time 12:50PM | Arrival Time 11:59PM | Duration 10h09 | Departure days Everyday | Cheapest price $67 |
Live departures
Panama City, FL to Orlando, FL bus times
The table below shows live departures for Panama City, FL to Orlando, FL buses for tomorrow, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| +FlixBus | 7:30 AM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 8h50 | 5:20 PM Orlando, The Florida Mall, FL | 1 transfer | |
| +FlixBus | 7:30 AM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 8h00 | 4:30 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
| +FlixBus | 12:50 PM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 12h00 | 1:50 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Panama City, FL to Orlando, FL buses with Omio?
Greyhound operates all buses services from Panama City, FL to Orlando, FL.
Omio is an official ticket reseller for all your travel options from Panama City, FL to Orlando, FL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Panama City, FL to Orlando, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Panama City, FL to Orlando, FL.
Bus providers: Greyhound from Panama City, FL to Orlando, FLYou can travel by bus between Panama City, FL to Orlando, FL with Greyhound for as low as $68. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
10h 9m
Cheapest Price
$96
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Orlando, FL
Things to do in Orlando, FL
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
- Recommended
Orange County Regional History Center
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
- Recommended
Rollins Museum of Art
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
- Must visit
Lake Eola Park
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
- Must visit
Park Avenue
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
- Recommended
Church Street District
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
Florida Catfish
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
- Gluten-free
Florida Shrimp
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
- Vegetarian
- Vegan
- Gluten-free
Cafecito
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Black Bean Deli
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Linda's La Cantina
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
The Ravenous Pig
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
US Dollar ($)
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Average meal costs
- Budget
- $10-15 for fast food or casual counter service.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
FAQs: Bus from Panama City, FL to Orlando, FL
Find answers to the most common questions about traveling from Panama City, FL to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Panama City, FL to Orlando, FL can start from as little as $68 when you book in advance. The average bus ticket price for Panama City, FL to Orlando, FL is $104 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Panama City, FL to Orlando, FL is 8h 0m to travel the 280 miles (452 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Panama City, FL to Orlando, FL leaves at 4:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Panama City, FL to Orlando, FL leaves at 11:40 PM.
There are 2 buses a day from Panama City, FL to Orlando, FL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Panama City, FL to Orlando, FL, you can count on Greyhound for the best way to get you to Orlando, FL. You can also check all possible bus companies who offer a service between Panama City, FL and Orlando, FL and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 2 ways to travel between Panama City, FL and Orlando, FL including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Panama City, FL to Orlando, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Panama City, FL to Orlando, FL for bus company Greyhound.
Whether you can cancel your bus ticket from Panama City, FL to Orlando, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Panama City, FL to Orlando, FL.
Yes, the following luggage options are included when booking a bus ticket from Panama City, FL to Orlando, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Panama City, FL to Orlando, FL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Panama City, FL to Orlando, FL.
You can reserve your seat on the bus from Panama City, FL to Orlando, FL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Panama City, FL to Orlando, FL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Panama City, FL to Orlando, FL with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Orlando, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like theme parks and popular tourist spots. Common scams include overpriced taxi rides, timeshare presentations that pressure visitors, and fake ticket sellers near major attractions. It's important to use authorized transportation services and purchase tickets from official vendors to avoid fraud. Additionally, travelers should stay aware of their surroundings and avoid poorly lit or isolated areas at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Panama City, FL to Orlando, FL
Most Panama City, FL to Orlando, FL buses use the Panama City Beach, Back Beach Rd (Shell Gas Station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Panama City, FL and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Panama City
Arrival bus stations in Orlando
Orlando, N John Young Pkwy (Greyhound Bus Station)
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $2 · every ~5 min
Most popular bus connections from Panama City, FL
More options for your journey from Panama City, FL to Orlando, FL
Here are some other resources that might have the information you need
Most popular buses to and from Orlando, FL and Panama City, FL
Most popular bus connections to Orlando, FL
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