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The cheapest and fastest buses from Panama City, FL to Orlando, FL
Showing times, prices and bookable tickets for Sep 18
Cheapest price on Sep 18
$74
Average ticket price on Sep 18
$75
Fastest journey on Sep 18
8 h
Average journey duration on Sep 18
9 h
Buses on Sep 18
3
Distance
452 km
Cheap tickets
The best way to find a cheap bus ticket from Panama City, FL to Orlando, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Panama City, FL to Orlando, FL will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $74.
Fast buses
It's difficult to get from Panama City, FL to Orlando, FL without transferring at least once.
+
FlixBus7:30 AM8h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL4:30 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$741One-way1 transfer- +FlixBus12:50 PM10h09Panama City Beach, Back Beach Rd (Shell Gas Station), FL11:59 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$751One-way1 transfer
- +FlixBus7:30 AM8h50Panama City Beach, Back Beach Rd (Shell Gas Station), FL5:20 PMOrlando, The Florida Mall, FL$761One-way1 transfer
- +FlixBus7:30 AM8h00Panama City Beach, Back Beach Rd (Shell Gas Station), FL4:30 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$741One-way1 transfer
- +FlixBus7:30 AM8h50Panama City Beach, Back Beach Rd (Shell Gas Station), FL5:20 PMOrlando, The Florida Mall, FL$761One-way1 transfer
- +FlixBus12:50 PM10h09Panama City Beach, Back Beach Rd (Shell Gas Station), FL11:59 PMOrlando, N John Young Pkwy (Greyhound Bus Station)$751One-way1 transfer
Travel Information
Compare bus for Panama City, FL to Orlando, FL
Omio recommends booking the bus as it is the most popular option from Panama City, FL to Orlando, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $103 For those with little time, consider booking a bus, which has an average total journey time of 8h 53m. Average ticket prices depend on the travel mode: a bus costs an average of $103, while a bus costs an average of $103.
Distance: 280 miles (452 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$103 Average price Cheapest | $70 Average price (fuel + tolls) |
8h 53m Average total duration Fastest 8h 23m Onboard + 30m Additional time* | 5h 37m Average total duration (door-to-door) |
Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
The cheapest way to travel from Panama City, FL to Orlando, FL is a bus with an average price of $103.
This is compared to other travel options from Panama City, FL to Orlando, FL:
A bus is $668 less than a flight for this route with tickets for a flight from Panama City, FL to Orlando, FL costing on average $771.
The fastest way to travel from Panama City, FL to Orlando, FL is by flight with an average journey time of 4h 24m.
Other travel options to Orlando, FL take longer:
Bus takes on average 8h 23m.
Yes, you can take a bus between Panama City, FL and Orlando, FL.
We recommend using the bus as it is the most popular way to get from Panama City, FL to Orlando, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $103 compared to roughly $70 in fuel and tolls — a saving of about $-32.99. The journey takes 8h 23m versus 5h 37m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Panama City, FL to Orlando, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:30AM | Arrival Time 06:45PM | Duration 10h15 | Departure days Wed, Thu | Cheapest price $76 |
Operator FlixBus | Departure Time 07:30AM | Arrival Time 05:20PM | Duration 8h50 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $62 |
Operator Greyhound | Departure Time 12:50PM | Arrival Time 11:59PM | Duration 10h09 | Departure days Everyday | Cheapest price $67 |
Live departures
Panama City, FL to Orlando, FL bus times
The table below shows live departures for Panama City, FL to Orlando, FL buses for tomorrow, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 7:30 AM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 8h50 | 5:20 PM Orlando, The Florida Mall, FL | 1 transfer | |
| FlixBus+ | 7:30 AM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 8h00 | 4:30 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
| +FlixBus | 12:50 PM Panama City Beach, Back Beach Rd (Shell Gas Station), FL | 10h09 | 11:59 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Panama City, FL to Orlando, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Sep 18
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Why should you book Panama City, FL to Orlando, FL buses with Omio?
FlixBus as well as Greyhound offer buses services from Panama City, FL to Orlando, FL.
Omio is an official ticket reseller for all your travel options from Panama City, FL to Orlando, FL.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Panama City, FL to Orlando, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Panama City, FL to Orlando, FL.
Journey information
Overview: Bus from Panama City, FL to Orlando, FL
USAUSA
Buses from Panama City, FL to Orlando, FL run on average 3 times per day, taking around 8h 23m. Cheap bus tickets for this journey start at $64 if you book in advance.
The earliest bus runs at 04:00, the last at 23:40. The fastest bus covers the 280 miles (452 km) distance in 7h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 280 miles (452 km) |
Average bus duration 8h 23m |
Cheapest ticket price $64 |
Buses per day 3 |
Fastest bus 7h 10m |
First bus 4:00 AM |
Last bus 11:40 PM |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound from Panama City, FL to Orlando, FLYou can travel by bus between Panama City, FL to Orlando, FL with FlixBus, Greyhound for as low as $64. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
7h 10m
Cheapest FlixBus Price
$64
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 5m
Cheapest Greyhound Price
$64
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Orlando, FL
Things to do in Orlando, FL
Discover the best of Orlando, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Orlando, FL trip today.
- Recommended
Orange County Regional History Center
Major local history museum in a restored 1927 courthouse, covering Central Florida's past through engaging permanent and special exhibits.
- Recommended
Rollins Museum of Art
Smithsonian-affiliated art museum with American, African, and ancient works, plus strong rotating exhibitions in Winter Park.
- Must visit
Lake Eola Park
Orlando's signature urban park with lake views, swan boats, skyline scenes, and frequent festivals in the city center.
- Must visit
Park Avenue
Upscale main street area famous for boutiques, brick streets, and a polished small-town atmosphere in nearby Winter Park.
- Recommended
Church Street District
Lively entertainment district with nightlife, murals, and historic architecture around downtown's Church Street corridor.
Florida Catfish
A Central Florida favorite of smoked or fried local catfish, often served with hushpuppies and grits. It reflects the region's freshwater fishing and Southern roots.
- Gluten-free
Florida Shrimp
Fresh Atlantic or Gulf shrimp, commonly peel-and-eat, grilled, or fried. It is a staple across Florida and prized in Orlando seafood spots for its regional freshness.
- Vegetarian
- Vegan
- Gluten-free
Cafecito
Cuban coffee sweetened during brewing for a bold, syrupy shot. Popular in Central Florida's Latin communities, it is a daily ritual and local caffeine classic.
Black Bean Deli
Popular Cuban cafe serving strong cafecito, Cuban sandwiches, and pastries in a busy, no-frills neighborhood setting.
Linda's La Cantina
Historic casual seafood house known for Florida gator tail, frog legs, and laid-back Old Florida charm near downtown Orlando.
The Ravenous Pig
Refined restaurant in Winter Park highlighting Florida seafood and seasonal Southern ingredients in an elegant but relaxed space.
US Dollar ($)
Moderate for a major US tourist city. Theme parks and hotels raise trip costs, while casual dining and ride-hailing are widely available at typical US urban prices.
Average meal costs
- Budget
- $10-15 for fast food or casual counter service.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis or ride-hailing, and small change or up to 10% at cafes if table service is provided.
FAQs: Bus from Panama City, FL to Orlando, FL
Find answers to the most common questions about traveling from Panama City, FL to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Panama City, FL to Orlando, FL can start from as little as $64 when you book in advance. The average bus ticket price for Panama City, FL to Orlando, FL is $103 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Panama City, FL to Orlando, FL is 7h 10m to travel the 280 miles (452 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Panama City, FL to Orlando, FL leaves at 4:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Panama City, FL to Orlando, FL leaves at 11:40 PM.
There are 3 buses a day from Panama City, FL to Orlando, FL which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Panama City, FL to Orlando, FL, you can count on FlixBus, Greyhound for the best way to get you to Orlando, FL. You can also check all possible bus companies who offer a service between Panama City, FL and Orlando, FL and compare the amenities they offer before buying a bus ticket.
When departing from Panama City, FL , you have various bus station options to start your journey from including Panama City Beach, Back Beach Rd (Shell Gas Station), FL . When arriving in Orlando, FL , you can end your journey in bus stations like Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL, Buena Ventura Lakes, Kissimmee .Passengers board the bus most frequently from Panama City Beach, Back Beach Rd (Shell Gas Station), FL, which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Orlando, N John Young Pkwy (Greyhound Bus Station), located 3 away from the city centre.
A trip to Orlando, FL from Panama City, FL is worth doing but not as a day trip with a journey time of 7h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Panama City, FL to Orlando, FL is January.
Yes, you can take a bus between Panama City, FL and Orlando, FL.
Yes, the following accessibility options are available when taking the bus from Panama City, FL to Orlando, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Panama City, FL to Orlando, FL for bus company FlixBus, Greyhound.
Some of the most interesting sights to explore in Orlando, FL are:
- Walt Disney World Resort, a massive entertainment complex featuring theme parks, water parks, and resorts
- Universal Orlando Resort, a popular destination with thrilling rides, shows, and attractions based on movies and TV shows
- SeaWorld Orlando, a marine-themed park offering animal exhibits, shows, and rides
- Kennedy Space Center Visitor Complex, an educational attraction showcasing NASA's space exploration history and offering interactive exhibits
- Leu Gardens, a beautiful botanical garden with a variety of plant collections and scenic landscapes.
The best things to do in Orlando, FL include:
- ICON Park, a vibrant entertainment complex with dining, shopping, and the iconic Wheel for panoramic views
- Explore the vibrant nightlife and live entertainment at Church Street District
- Enjoy a day of shopping and dining at The Mall at Millenia
- Experience the natural beauty and wildlife at Wekiwa Springs State Park
- Visit the Orlando Science Center for interactive exhibits and planetarium shows.
Whether you can cancel your bus ticket from Panama City, FL to Orlando, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Panama City, FL to Orlando, FL.
Yes, the following luggage options are included when booking a bus ticket from Panama City, FL to Orlando, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Panama City, FL to Orlando, FL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Panama City, FL to Orlando, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Panama City, FL to Orlando, FL with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Panama City, FL to Orlando, FL with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Panama City, FL to Orlando, FL with the following bus company: FlixBus, Greyhound.
Since neither Panama City, FL nor Orlando, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Panama City, FL to Orlando, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Orlando, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like theme parks and popular tourist spots. Common scams include overpriced taxi rides, timeshare presentations that pressure visitors, and fake ticket sellers near major attractions. It's important to use authorized transportation services and purchase tickets from official vendors to avoid fraud. Additionally, travelers should stay aware of their surroundings and avoid poorly lit or isolated areas at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Panama City, FL to Orlando, FL
Most Panama City, FL to Orlando, FL buses use the Panama City Beach, Back Beach Rd (Shell Gas Station) to Orlando, N John Young Pkwy (Greyhound Bus Station) station pair, with some services arriving at Orlando, The Florida Mall. Use this guide to compare Panama City, FL and Orlando, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Panama City
Arrival bus stations in Orlando
Which Orlando, FL station do buses from Panama City, FL arrive at?
Buses from Panama City, FL to Orlando, FL most often arrive at Orlando, N John Young Pkwy (Greyhound Bus Station). Some services arrive at Orlando, The Florida Mall, so check your ticket before travel to confirm your Orlando, FL arrival station.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $2 · every ~5 min
Most popular bus connections from Panama City, FL
More options for your journey from Panama City, FL to Orlando, FL
Here are some other resources that might have the information you need
Most popular buses to and from Orlando, FL and Panama City, FL
Most popular bus connections to Orlando, FL
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