Travel Information
Compare bus and flight for Orlando, FL to Panama City, FL
Omio recommends booking the bus as it is the most popular option from Orlando, FL to Panama City, FL among Omio's users. If you are prioritising price take the bus with prices starting from €39. For those with little time consider booking a bus which can get you there in 8h 55m. The ticket price range depends on the travel mode: a bus costs an average of €39, and a flight costs an average of €363.
Distance: 280 miles (452 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€57 Average price Cheapest | €481 Average price |
9h 25m Average total duration Fastest 8h 55m Onboard + 30m Additional time* | 14h 9m Average total duration 11h 9m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Orlando, FL to Panama City, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Orlando, FL to Panama City, FL
Buses from Orlando, FL to Panama City, FL run on average 2 times per day, taking around 8h 55m. Cheap bus tickets for this journey start at $48 (€39) if you book in advance.
There are 1 buses per day. The earliest bus runs at 05:40, the last at 12:50. The fastest bus covers the 280 miles (452 km) distance in 8h 15m.
Distance 280 miles (452 km) |
Average bus duration 8h 55m |
Cheapest ticket price $48 (€39) |
Buses per day 2 |
Direct buses 1 |
Fastest bus 8h 15m |
First bus 05:40 |
Last bus 12:50 |
Bus providers: Greyhound from Orlando, FL to Panama City, FLYou can travel by bus between Orlando, FL to Panama City, FL with Greyhound for as low as $48 (€39). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Orlando, FL to Panama City, FL
Find answers to the most common questions about traveling from Orlando, FL to Panama City, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Panama City, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Orlando, FL to Panama City, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Orlando, FL to Panama City, FL
Most popular bus connections from Orlando, FL
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