Orlando, FL to Panama City, FL bus with FlixBus

Sun, Sep 20
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The cheapest and fastest buses from Orlando, FL to Panama City, FL

Showing times, prices and bookable tickets for Sep 20

Cheapest price on Sep 20

€57

Average ticket price on Sep 20

€58

Fastest journey on Sep 20

8 h 45 m

Average journey duration on Sep 20

9 h 12 m

Buses on Sep 20

3

Distance

452 km

Cheap tickets

The best way to find a cheap bus ticket from Orlando, FL to Panama City, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Orlando, FL to Panama City, FL will cost around €58 if you buy it on the day, but the cheapest tickets can be found for only €57.

Fast buses

It's difficult to get from Orlando, FL to Panama City, FL without transferring at least once.

  • FlixBusFlixBus+Greyhound
    1:05 PM9h30
    Orlando, The Florida Mall, FL
    9:35 PMPanama City Beach, Back Beach Rd (Shell Gas Station), FL
    571One-way
    1 transfer
  • Greyhound ·
    5:40 AM9h20
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    2:00 PMPanama City Beach, Back Beach Rd (Shell Gas Station), FL
    581One-way
    1 transfer
  • FlixBusFlixBus+Greyhound
    1:50 PM8h45
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    9:35 PMPanama City Beach, Back Beach Rd (Shell Gas Station), FL
    581One-way
    1 transfer

Travel Information

Compare bus for Orlando, FL to Panama City, FL

Omio recommends booking the flight as it is the most popular option from Orlando, FL to Panama City, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €68 For those with little time, consider booking a flight, which has an average total journey time of 7h 35m. Average ticket prices depend on the travel mode: a bus costs an average of €68, while a flight costs an average of €938.

Distance: 280 miles (452 km)

Compare bus with

Bus
Most popular
Flight
Driving

€68

Average price

Cheapest

€938

Average price

€57

Average price

(fuel + tolls)

8h 40m

Average total duration

8h 10m

Onboard

+

30m

Additional time*

7h 35m

Average total duration

Fastest

5h 35m

Onboard

+

2h 0m

Additional time*

5h 22m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Orlando, FL to Panama City, FL is a bus with an average price of €68.

This is compared to other travel options from Orlando, FL to Panama City, FL:

A bus is €871 less than a flight for this route with tickets for a flight from Orlando, FL to Panama City, FL costing on average €938.

The fastest way to travel from Orlando, FL to Panama City, FL is by flight with an average journey time of 5h 35m.

Other travel options to Panama City, FL take longer:

Bus takes on average 8h 10m.

Yes, you can take a bus between Orlando, FL and Panama City, FL.
We recommend using the bus as it is the most popular way to get from Orlando, FL to Panama City, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around €68 compared to roughly €57 in fuel and tolls — a saving of about €-10.87. The journey takes 8h 10m versus 5h 22m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Orlando, FL to Panama City, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
04:35AM
Arrival Time
09:35PM
Duration
18h00
Departure days
Tue
Cheapest price
46
Operator
Greyhound
Departure Time
05:40AM
Arrival Time
02:00PM
Duration
9h20
Departure days
Everyday
Cheapest price
45
Operator
Greyhound
Departure Time
07:10AM
Arrival Time
09:35PM
Duration
15h25
Departure days
Wed
Cheapest price
46
Operator
Greyhound
Departure Time
10:15AM
Arrival Time
09:35PM
Duration
12h20
Departure days
Tue
Cheapest price
47
Operator
FlixBus
Departure Time
12:30PM
Arrival Time
09:35PM
Duration
10h05
Departure days
Wed
Cheapest price
46
Operator
FlixBus
Departure Time
01:05PM
Arrival Time
09:35PM
Duration
9h30
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
49
Operator
FlixBus
Departure Time
01:50PM
Arrival Time
09:35PM
Duration
8h45
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
50

Live departures

Orlando, FL to Panama City, FL bus times

The table below shows live departures for Orlando, FL to Panama City, FL buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 5:40 AM Orlando, N John Young Pkwy (Greyhound Bus Station)
9h20
2:00 PM Panama City Beach, Back Beach Rd (Shell Gas Station), FL1 transfer
FlixBusFlixBus+Greyhound1:05 PM Orlando, The Florida Mall, FL
9h30
9:35 PM Panama City Beach, Back Beach Rd (Shell Gas Station), FL1 transfer
FlixBusFlixBus+Greyhound1:50 PM Orlando, N John Young Pkwy (Greyhound Bus Station)
8h45
9:35 PM Panama City Beach, Back Beach Rd (Shell Gas Station), FL1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Orlando, FL to Panama City, FL by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25
Sat
Sep 26

Why should you book Orlando, FL to Panama City, FL buses with Omio?

Greyhound as well as FlixBus offer buses services from Orlando, FL to Panama City, FL.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Panama City, FL.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Orlando, FL to Panama City, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Orlando, FL to Panama City, FL.

Journey information

Overview: Bus from Orlando, FL to Panama City, FL

USAUSA
USAUSA
Icon of bus

Buses from Orlando, FL to Panama City, FL run on average 3 times per day, taking around 8h 10m. Cheap bus tickets for this journey start at €49 if you book in advance.

The earliest bus runs at 04:40, the last at 23:40. The fastest bus covers the 280 miles (452 km) distance in 7h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
280 miles (452 km)
Average bus duration
8h 10m
Cheapest ticket price
€49
Buses per day
3
Fastest bus
7h 0m
First bus
4:40 AM
Last bus
11:40 PM
Cheapest Month
May
Cheapest Day
Thu
High Season
Jul - Sep
Low Season
Jan - Mar
Best time to book
21 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Orlando, FL to Panama City, FLYou can travel by bus between Orlando, FL to Panama City, FL with FlixBus, Greyhound for as low as €49. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
7h 0m
Cheapest FlixBus Price
€49
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 40m
Cheapest Greyhound Price
€50
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

Complete guide to Panama City, FL

Things to do in Panama City, FL

Discover the best of Panama City, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Panama City, FL trip today.

  • Recommended

Bay County History Museum

Local history museum in a waterfront estate with exhibits on Native cultures, settlement, industry, and life in Bay County.

  • Recommended

Man in the Sea Museum

Compact museum dedicated to military and civilian aviation, featuring aircraft displays, artifacts, and regional flight history.

Panama City Center for the Arts

Specialty museum exploring diving technology and underwater exploration through helmets, submersibles, and hands-on displays.

FAQs: Bus from Orlando, FL to Panama City, FL

Find answers to the most common questions about traveling from Orlando, FL to Panama City, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Panama City, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to Panama City, FL can start from as little as €49 when you book in advance. The average bus ticket price for Orlando, FL to Panama City, FL is €68 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Panama City, FL is 7h 0m to travel the 280 miles (452 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Panama City, FL leaves at 4:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Panama City, FL leaves at 11:40 PM.
There are 3 buses a day from Orlando, FL to Panama City, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Panama City, FL, you can count on Greyhound, FlixBus for the best way to get you to Panama City, FL. You can also check all possible bus companies who offer a service between Orlando, FL and Panama City, FL and compare the amenities they offer before buying a bus ticket.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL . When arriving in Panama City, FL , you can end your journey in bus stations like Panama City Beach, Back Beach Rd (Shell Gas Station), FL .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Panama City Beach, Back Beach Rd (Shell Gas Station), FL, located 3 away from the city centre.
A trip to Panama City, FL from Orlando, FL is worth doing but not as a day trip with a journey time of 7h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Orlando, FL to Panama City, FL is May.
Yes, you can take a bus between Orlando, FL and Panama City, FL.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Panama City, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Panama City, FL for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Panama City, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Panama City, FL.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Panama City, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Panama City, FL:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Panama City, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Panama City, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Panama City, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Panama City, FL with the following bus company: Greyhound, FlixBus.
Since neither Orlando, FL nor Panama City, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Panama City, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Panama City, FL, travelers should be cautious of petty theft and pickpocketing, especially in crowded areas and popular beach spots. Common scams include overpriced taxi rides and unofficial ticket sellers for attractions or tours. It’s advisable to use licensed transportation services and stay aware of surroundings, particularly at night. Always safeguard personal belongings and avoid sharing too much personal information with strangers.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Orlando, FL to Panama City, FL

Most Orlando, FL to Panama City, FL buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Panama City Beach, Back Beach Rd (Shell Gas Station) station pair. Use this guide to compare Orlando, FL and Panama City, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Orlando
Arrival bus stations in Panama City

Which Orlando, FL station do buses to Panama City, FL leave from?

Buses from Orlando, FL to Panama City, FL leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre

Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:

Bus125 · 40m · €2 · every ~6 min
125 · 41m · €2 · every ~6 min

Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services

Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).

Tickets and information

Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).

Parking, taxis and toilets

Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.

Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport

Getting to Orlando, The Florida Mall from Orlando city centre

Bus42 · 26m · €2 · every ~5 min

More options for your journey from Orlando, FL to Panama City, FL

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Panama City, FLOrlando, FL to Panama City, FL bus

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