- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Cheapest price on Sep 19
$49
Average ticket price on Sep 19
$51
Fastest journey on Sep 19
9 h 25 m
Average journey duration on Sep 19
9 h 25 m
Buses on Sep 19
2
Distance
250 km
The best way to find a cheap bus ticket from Nyon to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nyon to Milan will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $49.
On Sat, Sep 19, we found 2 buses from Nyon to Milan, including 2 direct services.
On Sat, Sep 19 the direct buses cover the 250 km distance in an average of 9 h 25 m but if you time it right, some buses will get you there in just 9 h 25 m .
On Sat, Sep 19 the slowest buses will take 9 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Nyon to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $84 For those with little time, consider booking a flight, which has an average total journey time of 4h 53m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.2kg. Average ticket prices depend on the travel mode: a bus costs an average of $84, while a flight costs an average of $572.
Distance: 155 miles (250 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$84 Average price Cheapest | $126 Average price | $572 Average price | $250 Average price (fuel + tolls) |
8h 59m Average total duration 8h 29m Onboard + 30m Additional time* | 5h 16m Average total duration 4h 46m Onboard + 30m Additional time* | 4h 53m Average total duration Fastest 2h 53m Onboard + 2h 0m Additional time* | 4h 11m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest | 0.7 - 1.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Nyon to Milan:
A bus is $42 less than a train for this route with tickets for a train from Nyon to Milan costing on average $126.
A bus is $488 less than a flight for this route with tickets for a flight from Nyon to Milan costing on average $572.
Other travel options to Milan take longer:
Train takes on average 4h 46m.
Bus takes on average 8h 29m.
Tickets start at around $84 compared to roughly $250 in fuel and tolls — a saving of about $166. The journey takes 8h 29m versus 4h 11m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:40AM | Arrival Time 09:55PM | Duration 12h15 | Departure days Mon, Fri | Cheapest price $59 |
Operator FlixBus | Departure Time 10:45AM | Arrival Time 08:20PM | Duration 9h35 | Departure days Mon | Cheapest price $54 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 08:55PM | Duration 8h30 | Departure days Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 12:30PM | Arrival Time 09:55PM | Duration 9h25 | Departure days Sat, Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 09:55PM | Duration 8h30 | Departure days Mon, Fri | Cheapest price $53 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 10:55PM | Duration 9h25 | Departure days Tue, Wed, Sat | Cheapest price $51 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 11:55PM | Duration 9h25 | Departure days Mon | Cheapest price $48 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 05:25AM | Duration 12h35 | Departure days Mon, Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 05:35PM | Arrival Time 11:55PM | Duration 6h20 | Departure days Fri | Cheapest price $58 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 05:25AM | Duration 9h25 | Departure days Mon, Thu | Cheapest price $56 |
The table below shows live departures for Nyon to Milan buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:40 AM Thonon-les-Bains, Gare routière du Lycée de la Versoie | 12h15 | 9:55 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 1:25 PM Genève, Aéroport | 8h30 | 9:55 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 4:50 PM Thonon-les-Bains, Gare routière du Lycée de la Versoie | 12h35 | 5:25 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 5:35 PM Genève, Aéroport | 6h20 | 11:55 PM Milano, Autostazione Lampugnano | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Nyon to Milan run on average 4 times per day, taking around 8h 29m. Cheap bus tickets for this journey start at $46 but you can travel from only $45 by train.
The earliest bus runs at 00:38, the last at 23:45. The fastest bus covers the 155 miles (250 km) distance in 5h 25m.
Distance 155 miles (250 km) |
Average bus duration 8h 29m |
Cheapest ticket price $46 |
Buses per day 4 |
Fastest bus 5h 25m |
First bus 12:38 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 1 day |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Orio al Serio, Milan Bergamo Airport (Bus station) -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Nyon to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Nyon to Milan buses use the Genève, Aéroport to Milano, Autostazione Lampugnano station pair. Use this guide to compare Nyon and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Here are some other resources that might have the information you need