The cheapest and fastest buses from Madrid to Colonia de Santa Ana
Cheapest price
$25
Average price
$33
Fastest journey
6 h 25 m
Average duration
8 h 13 m
Buses per day
2
Distance
383 km
The best way to find a cheap bus ticket from Madrid to Colonia de Santa Ana is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Colonia de Santa Ana will cost around $33 if you buy it on the day, but the cheapest tickets can be found for only $25.
Of the 2 buses that leave Madrid for Colonia de Santa Ana on Fri, May 08, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 08 the direct buses cover the 383 km distance in an average of 8 h 13 m but if you time it right, some buses will get you there in just 6 h 25 m .
On Fri, May 08 the slowest buses will take 10 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
10:30 PM6h25Madrid4:55 AMColonia de Santa Ana$251One-way0 transfers
10:30 AM10h00Madrid8:30 PMColonia de Santa Ana$421One-way0 transfers
10:30 PM6h25Madrid4:55 AMColonia de Santa Ana$251One-way0 transfers
10:30 AM10h00Madrid8:30 PMColonia de Santa Ana$421One-way0 transfers
Travel Information
Compare bus, train, and flight for Madrid to Colonia de Santa Ana
Omio recommends booking the train as it is the most popular option from Madrid to Colonia de Santa Ana among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a flight which can get you there in 1h 10m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $40.
Distance: 237 miles (383 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$32 Average price Cheapest | $48 Average price | $123 Average price |
6h 55m Average total duration 6h 25m Onboard + 30m Additional time* | 3h 21m Average total duration 2h 51m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.1 - 2.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Colonia de Santa Ana:
A bus is $16 (€13) less than a train for this route with tickets for a train from Madrid to Colonia de Santa Ana costing on average $48 (€38).
A bus is $91 (€73) less than a flight for this route with tickets for a flight from Madrid to Colonia de Santa Ana costing on average $123 (€99).
Other travel options to Colonia de Santa Ana take longer:
Train takes on average 2h 51m.
Bus takes on average 6h 25m.
Live departures
Madrid to Colonia de Santa Ana bus times
The table below shows live departures for Madrid to Colonia de Santa Ana buses for today, Thursday, May 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:30 PM Madrid | 6h25 | 4:55 AM Colonia de Santa Ana | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Madrid to Colonia de Santa Ana by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 08
May 09
May 10
May 11
May 12
May 13
May 14
Why should you book Madrid to Colonia de Santa Ana buses with Omio?
Why book with Omio vs Grupo Interbus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Grupo Interbus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Madrid to Colonia de Santa Ana.
Why book with Omio over Checkmybus or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Madrid to Colonia de Santa Ana.
Journey information
Overview: Bus from Madrid to Colonia de Santa Ana
Buses from Madrid to Colonia de Santa Ana run on average 5 times per day, taking around 6h 25m. Cheap bus tickets for this journey start at $22 (€18) but you can travel from only $19 (€15) by train.
There are 5 buses per day. The earliest bus runs at 00:35, the last at 23:35. The fastest bus covers the 237 miles (383 km) distance in 6h 25m.
Distance 237 miles (383 km) |
Average bus duration 6h 25m |
Cheapest ticket price $22 (€18) |
Buses per day 5 |
Direct buses 5 |
Fastest bus 6h 25m |
First bus 12:35 AM |
Last bus 11:35 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Apr - Jun |
Busiest Day Sun |
Least Busy Day Wed |
Best time to book 14 days |
Bus providers: Grupo Interbus from Madrid to Colonia de Santa AnaYou can travel by bus between Madrid to Colonia de Santa Ana with Grupo Interbus for as low as $19 (€15). When you search for schedules and tickets, Omio will show you the best journey
Grupo Interbus
FAQs: Bus from Madrid to Colonia de Santa Ana
Find answers to the most common questions about traveling from Madrid to Colonia de Santa Ana by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Colonia de Santa Ana, this guide helps you travel smarter and with confidence.

- Grupo Interbus
- Assistance
- Priority seating
- Accessible restrooms.
- Grupo Interbus
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- Grupo Interbus
- One carry-on bag up to 10kg (55x40x20) and one checked bag up to 20kg (80x50x30).
- Grupo Interbus
- 10€ per additional bag.
- Grupo Interbus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Madrid to Colonia de Santa Ana
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
More options for your journey from Madrid to Colonia de Santa Ana
Here are some other resources that might have the information you need


