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The cheapest and fastest buses from Lake City, FL to Chicago, IL
Showing times and prices for Feb 22
Cheapest price
$442
Average price
$442
Fastest journey
22 h 50 m
Average duration
22 h 50 m
Buses per day
1
Distance
1372 km
Cheap tickets
The best way to find a cheap bus ticket from Lake City, FL to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lake City, FL to Chicago, IL will cost around $442 if you buy it on the day, but the cheapest tickets can be found for only $442.
Fast buses
It's difficult to get from Lake City, FL to Chicago, IL without transferring at least once.
09:35AM22h50
Lake City, FL08:25AMChicago, IL
$4421One-way
1 transfer
09:35AM22h50
Lake City, FL08:25AMChicago, IL
$4421One-way
1 transfer
Live departures
Lake City, FL to Chicago, IL bus times
The table below shows live departures for Lake City, FL to Chicago, IL buses for today, Saturday, February 21. You can also manually refresh the results below to see updated bus journeys.
Last updated at 12:01 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:30 PM Lake City, FL | 21h45 | 11:15 AM Chicago, IL | 1 transfer | |
| Sunday, February 22 | |||||
| 9:35 AM Lake City, FL | 22h50 | 8:25 AM Chicago, IL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lake City, FL to Chicago, IL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Feb 22
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Why should you book Lake City, FL to Chicago, IL buses with Omio?
Greyhound operates all buses services from Lake City, FL to Chicago, IL.
Omio is an official ticket reseller for all your travel options from Lake City, FL to Chicago, IL.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Journey information
Overview: Bus from Lake City, FL to Chicago, IL
USAUSA
Buses from Lake City, FL to Chicago, IL run on average 6 times per day, taking around 22h 20m. Cheap bus tickets for this journey start at $324 (€258) if you book in advance.
The earliest bus runs at 06:10, the last at 22:00. The fastest bus covers the 852 miles (1372 km) distance in 21h 45m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 852 miles (1372 km) |
Average bus duration 22h 20m |
Cheapest ticket price $324 (€258) |
Buses per day 6 |
Fastest bus 21h 45m |
First bus 06:10 |
Last bus 22:00 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from Lake City, FL to Chicago, ILYou can travel by bus between Lake City, FL to Chicago, IL with Greyhound for as low as $324 (€258). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
21h 45m
Cheapest Price
$324 (€258)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from Lake City, FL to Chicago, IL
Find answers to the most common questions about traveling from Lake City, FL to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Lake City, FL to Chicago, IL can start from as little as $324 (€258) when you book in advance. The average bus ticket price for Lake City, FL to Chicago, IL is $384 (€306) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Lake City, FL to Chicago, IL is 21h 45m to travel the 852 miles (1372 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Lake City, FL to Chicago, IL leaves at 6:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Lake City, FL to Chicago, IL leaves at 10:00 PM.
There are 6 buses a day from Lake City, FL to Chicago, IL which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Lake City, FL to Chicago, IL, you can count on Greyhound for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between Lake City, FL and Chicago, IL and compare the amenities they offer before buying a bus ticket.
A trip to Chicago, IL from Lake City, FL is worth doing but not as a day trip with a journey time of 21h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Lake City, FL to Chicago, IL is August.
Yes, you can take a bus between Lake City, FL and Chicago, IL.
Yes, the following accessibility options are available when taking the bus from Lake City, FL to Chicago, IL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Lake City, FL to Chicago, IL for bus company Greyhound.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U.S., offering free admission.
Whether you can cancel your bus ticket from Lake City, FL to Chicago, IL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Lake City, FL to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from Lake City, FL to Chicago, IL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Lake City, FL to Chicago, IL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Lake City, FL to Chicago, IL.
You can reserve your seat on the bus from Lake City, FL to Chicago, IL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Lake City, FL to Chicago, IL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Lake City, FL to Chicago, IL with the following bus company: Greyhound.
popular bus stations
Popular bus stations from Lake City, FL to Chicago, IL
Lake City
Chicago
The major bus station for departures in Lake City is Lake City, S Marion Ave (Lake City Greyhound Station). Find all the information you need to know about services, amenities and connections at Lake City, S Marion Ave (Lake City Greyhound Station) for your trip from Lake City to Chicago.
Lake City, S Marion Ave (Lake City Greyhound Station)
information
The major bus station for arrivals in Chicago is Chicago, Greyhound Bus Station. Find all the information you need to know about services, amenities and connections at Chicago, Greyhound Bus Station for your trip to Chicago from Lake City.
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
More options for your journey from Lake City, FL to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Lake City, FL
Most popular bus connections to Chicago, IL
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