- Must visit
Art Institute of Chicago
World-class art museum with masterpieces from Monet to Hopper and the famous Modern Wing.
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The cheapest and fastest buses from Lake City, FL to Chicago, IL
Showing times, prices and bookable tickets for Oct 10
Cheapest price on Oct 10
$263
Average ticket price on Oct 10
$263
Fastest journey on Oct 10
22 h 50 m
Average journey duration on Oct 10
22 h 50 m
Buses on Oct 10
1
Distance
1372 km
Cheap tickets
The best way to find a cheap bus ticket from Lake City, FL to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lake City, FL to Chicago, IL will cost around $263 if you buy it on the day, but the cheapest tickets can be found for only $263.
Fast buses
It's difficult to get from Lake City, FL to Chicago, IL without transferring at least once.
9:35 AM22h50Lake City, FL8:25 AMChicago, IL$2631One-way1 transfer
- 9:35 AM22h50Lake City, FL8:25 AMChicago, IL$2631One-way1 transfer
Journey information
Overview: Bus from Lake City, FL to Chicago, IL
USAUSA
Take a bus from Lake City, FL to Chicago, IL and enjoy the approximately 852 miles (1372 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 06:10, the last at 22:00.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 852 miles (1372 km) |
First bus 6:10 AM |
Last bus 10:00 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Lake City, FL to Chicago, IL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 09:35AM | Arrival Time 08:25AM | Duration 22h50 | Departure days Everyday | Cheapest price $263 |
Live departures
Lake City, FL to Chicago, IL bus times
The table below shows live departures for Lake City, FL to Chicago, IL buses for today, Friday, October 9. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:35 AM Lake City, FL | 22h50 | 8:25 AM Chicago, IL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Bus providers: Greyhound from Lake City, FL to Chicago, ILYou can travel by bus between Lake City, FL to Chicago, IL with Greyhound. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
22h 50m
Cheapest Greyhound Price
$263
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Chicago, IL
Things to do in Chicago, IL
Discover the best of Chicago, IL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago, IL trip today.
- Must visit
Field Museum
Major natural history museum with Sue the T. rex, ancient cultures, and strong family appeal.
- Must visit
Museum of Science and Industry
Hands-on science museum in a grand former fair building, popular for exhibits and a U-505 submarine.
- Must visit
Millennium Park
Lively lakefront park with Cloud Gate, Crown Fountain, gardens, and major public art in central Chicago.
- Must visit
Magnificent Mile
Famous shopping boulevard lined with architecture, hotels, riverfront views, and major city energy.
- Must visit
Chicago Riverwalk
Scenic pedestrian-friendly riverwalk with boat docks, public art, bridges, and standout skyline perspectives.
Deep-Dish Pizza
Deep-dish pizza is Chicago’s iconic pie with a tall buttery crust, layers of cheese and toppings, and chunky tomato sauce baked on top.
Chicago-Style Hot Dog
The Chicago-style hot dog is an all-beef frank on a poppy seed bun with mustard, relish, onion, tomato, pickle, peppers, and celery salt.
Italian Beef Sandwich
Italian beef is thin-sliced roast beef piled onto a roll, often dipped in savory juices and topped with sweet peppers or spicy giardiniera.
Johnnie's Beef
Classic spot for juicy Italian beef sandwiches, especially dipped and topped with spicy giardiniera, with a casual local feel.
Superdawg Drive-In
Legendary stand for Chicago-style hot dogs and char-grilled sausages, served fast in a no-frills local landmark.
Alinea
World-famous fine dining destination offering a highly creative tasting menu and refined service in an elegant setting.
US dollar ($)
Moderate for a major US city: hotels can be pricey, but transit is affordable and dining ranges from cheap eats to upscale options.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and optional small change at cafes.
FAQs: Bus from Lake City, FL to Chicago, IL
Find answers to the most common questions about traveling from Lake City, FL to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
The earliest bus from Lake City, FL to Chicago, IL leaves at 6:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Lake City, FL to Chicago, IL leaves at 10:00 PM.
When taking a bus from Lake City, FL to Chicago, IL, you can count on Greyhound for the best way to get you to Chicago, IL. You can also check all possible bus companies who offer a service between Lake City, FL and Chicago, IL and compare the amenities they offer before buying a bus ticket.
Yes, you can take a bus between Lake City, FL and Chicago, IL.
Yes, there are bathrooms on board the bus from Lake City, FL to Chicago, IL for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Lake City, FL to Chicago, IL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Lake City, FL to Chicago, IL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Lake City, FL to Chicago, IL.
Yes, the following luggage options are included when booking a bus ticket from Lake City, FL to Chicago, IL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Lake City, FL to Chicago, IL:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Lake City, FL to Chicago, IL.
You can reserve your seat on the bus from Lake City, FL to Chicago, IL with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Lake City, FL to Chicago, IL with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Lake City, FL to Chicago, IL with the following bus company: Greyhound.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Chicago, IL, travelers should be cautious of pickpocketing and purse snatching, especially in crowded areas like public transit and popular tourist spots. Common scams include fake charity solicitations and distraction thefts. It is advisable to stay alert in neighborhoods outside downtown after dark and use authorized transportation services to avoid unlicensed taxi scams. Keeping valuables secure and being aware of surroundings helps mitigate these risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Lake City, FL to Chicago, IL
Most Lake City, FL to Chicago, IL buses use the Lake City, S Marion Ave (Lake City Greyhound Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare Lake City, FL and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Lake City
Arrival bus stations in Chicago
Which Lake City, FL station do buses to Chicago, IL leave from?
Buses from Lake City, FL to Chicago, IL leave from Lake City, S Marion Ave (Lake City Greyhound Station). The station is from Lake City, FL city centre at 251 S Marion Ave, Lake City, FL 32025, USA.
Lake City, S Marion Ave (Lake City Greyhound Station)251 S Marion Ave, Lake City, FL 32025, USA
City-centre transport
Getting to Lake City, S Marion Ave (Lake City Greyhound Station) from Lake City city centre
TRUE
Lake City, S Marion Ave (Lake City Greyhound Station) bus station facilities and services
Lake City, S Marion Ave (Lake City Greyhound Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lake City, S Marion Ave (Lake City Greyhound Station). ATMs are available at Lake City, S Marion Ave (Lake City Greyhound Station).
Tickets and information
Ticket office support is available at Lake City, S Marion Ave (Lake City Greyhound Station).
Parking, taxis and toilets
Available at Lake City, S Marion Ave (Lake City Greyhound Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lake City, S Marion Ave (Lake City Greyhound Station): Basic accessibility features are present.
Which Chicago, IL station do buses from Lake City, FL arrive at?
Buses from Lake City, FL to Chicago, IL most often arrive at Chicago, Greyhound Bus Station. Some services arrive at Chicago, Union Station (Amtrak), so check your ticket before travel to confirm your Chicago, IL arrival station.
Chicago, Greyhound Bus Station630 W Harrison St, Chicago, IL 60607, USA
City-centre transport
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Bus7 · 8m · $4 · every ~6 min
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Chicago, Union Station (Amtrak)Chicago Union Station, 225 S Canal St, Chicago, IL 60606, USA
City-centre transport
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Bus28, 151 · 7m · $4 · every ~13 min
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
More options for your journey from Lake City, FL to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Lake City, FL
Most popular bus connections to Chicago, IL
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