- Must visit
Museum of Fine Arts, Houston
One of the largest art museums in the US, with major collections spanning antiquities to contemporary works across multiple buildings in the Museum District.
Cheapest price
$241
Average price
$241
Fastest journey
18 h 56 m
Average duration
18 h 56 m
Buses per day
1
Distance
1226 km
The best way to find a cheap bus ticket from Lake City, FL to Houston, TX is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lake City, FL to Houston, TX will cost around $241 if you buy it on the day, but the cheapest tickets can be found for only $241.
It's difficult to get from Lake City, FL to Houston, TX without transferring at least 2 times.


Omio recommends booking the bus as it is the most popular option from Lake City, FL to Houston, TX among Omio's users. If you are prioritising price take the bus with prices starting from $241. For those with little time consider booking a bus which can get you there in 18h 56m. The ticket price range depends on the travel mode: a bus costs an average of $241, and a bus costs an average of $241.
Distance: 761 miles (1226 km)
Most popular Bus | Driving |
|---|---|
$241 Average price Cheapest | $165 Average price (fuel + tolls) |
19h 26m Average total duration Fastest 18h 56m Onboard + 30m Additional time* | 11h 36m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 05:30PM | Arrival Time 12:26PM | Duration 18h56 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $241 |
The table below shows live departures for Lake City, FL to Houston, TX buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:30 PM Lake City, FL | 18h56 | 12:26 PM Houston, TX | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Lake City, FL to Houston, TX run on average 7 times per day, taking around 18h 56m. Cheap bus tickets for this journey start at $241 (€197) if you book in advance.
The earliest bus runs at 17:30, the last at 17:30. The fastest bus covers the 761 miles (1226 km) distance in 18h 54m.
Distance 761 miles (1226 km) |
Average bus duration 18h 56m |
Cheapest ticket price $241 (€197) |
Buses per day 7 |
Fastest bus 18h 54m |
First bus 5:30 PM |
Last bus 5:30 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Discover the best of Houston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Houston trip today.
One of the largest art museums in the US, with major collections spanning antiquities to contemporary works across multiple buildings in the Museum District.
The official visitor center for NASA Johnson Space Center, known for spacecraft displays, astronaut history, and tram tours to working NASA facilities.
A renowned free art museum with strong surrealist, Byzantine, and modern collections, set in a quiet campus popular with locals.
A major urban park with skyline views, trails, public art, and bayou scenery, widely considered one of Houston's best outdoor spaces.
A lively downtown park hosting art, events, gardens, and seasonal activities, making it one of the city's most visited public gathering spaces.
Houston's leading cultural area, packed with major museums, walkable streets, and one of the best concentrations of attractions in the city.
Slow-smoked beef brisket with a peppery bark, a cornerstone of Houston barbecue culture shaped by Texas smoking traditions.
Grilled skirt steak served sizzling with tortillas and fixings; Houston helped popularize Tex-Mex fajitas nationwide.
Soft tortillas filled with eggs, potatoes, cheese, or meats, reflecting Houston’s everyday Tex-Mex breakfast culture.
Established upscale steakhouse known for prime beef, polished service, and an extensive wine program.
Widely praised Houston barbecue spot known for brisket, ribs, and classic Texas sides in a lively, casual setting.
Well-known restaurant serving refined regional Mexican cuisine in an elegant but welcoming setting.
Moderate by U.S. big-city standards. Dining and transport are manageable, but hotels and car-related costs can add up.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis/rideshares 10-15%, hotel staff USD 2-5, and round up for coffee only if desired.
Find answers to the most common questions about traveling from Lake City, FL to Houston, TX by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Houston, TX, this guide helps you travel smarter and with confidence.

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