Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA bus with FlixBus

Fri, Dec 19
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The cheapest and fastest buses from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA

Showing times and prices for Dec 22

Cheapest price

$31

Average price

$33

Fastest journey

1 h 15 m

Average duration

1 h 32 m

Buses per day

13

Distance

117 km

Cheap tickets

The best way to find a cheap bus ticket from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA will cost around $33 if you buy it on the day, but the cheapest tickets can be found for only $31.

Fast buses

Of the 13 buses that leave Santa Fe Depot, San Diego, CA for Irvine Transportation Center, Irvine, CA on Mon, Dec 22, 13 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Mon, Dec 22 the direct buses cover the 117 km distance in an average of 1 h 32 m but if you time it right, some buses will get you there in just 1 h 15 m .

On Mon, Dec 22 the slowest buses will take 1 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBusFlixBus
03:55PM1h35
San Diego, Congress Street (Old Town Park), CA
05:30PMIrvine, West Peltason Dr (UCI Crawford Hall), CA
$311One-way
0 transfers
FlixBusFlixBus
04:15PM1h15
La Jolla, UCSD Health La Jolla Station, CA
05:30PMIrvine, West Peltason Dr (UCI Crawford Hall), CA
$311One-way
0 transfers
FlixBusFlixBus
11:55AM2h25
San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
02:20PMIrvine, West Peltason Dr (UCI Crawford Hall), CA
$321One-way
0 transfers
FlixBusFlixBus
12:15PM2h30
San Diego, Congress Street (Old Town Park), CA
02:45PMAnaheim, Regional Transportation Intermodal Center (ARTIC)
$321One-way
0 transfers
FlixBusFlixBus
12:15PM2h05
San Diego, Congress Street (Old Town Park), CA
02:20PMIrvine, West Peltason Dr (UCI Crawford Hall), CA
$321One-way
0 transfers

Santa Fe Depot, San Diego, CA - Irvine Transportation Center, Irvine, CACompare FlixBus, Greyhound

meinfernbus_flixbus
$19
1h 40m
11 a day
Power plugs
Wifi
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Seat reservation
greyhound
$22
1h 55m
5 a day
Power plugs
Wifi
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Seat reservation

Travel Information

Compare bus and train for Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA

Omio recommends booking the train as it is the most popular option from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA among Omio's users. If you are prioritising price take the bus with prices starting from €15. For those with little time consider booking a train which can get you there in 1h 49m. The ticket price range depends on the travel mode: a bus costs an average of €15, and a train costs an average of €24.

Distance: 72 miles (117 km)

Compare bus with

Bus
Most popular
Train

€18

Average price

Cheapest

€25

Average price

2h 37m

Average total duration

2h 7m

Onboard

+

30m

Additional time*

2h 19m

Average total duration

Fastest

1h 49m

Onboard

+

30m

Additional time*

FlixBus

Most popular bus company

Amtrak

Most popular train company

Direct Options

Direct Options

Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
06:45AM
Arrival Time
08:40AM
Duration
1h55
Departure days
Mon, Fri, Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
08:20AM
Arrival Time
10:10AM
Duration
1h50
Departure days
Mon
Cheapest price
$33
Operator
FlixBus
Departure Time
08:45AM
Arrival Time
10:10AM
Duration
1h25
Departure days
Mon
Cheapest price
$33
Operator
FlixBus
Departure Time
11:55AM
Arrival Time
02:20PM
Duration
2h25
Departure days
Mon, Fri, Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
12:15PM
Arrival Time
02:45PM
Duration
2h30
Departure days
Mon, Fri, Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
12:40PM
Arrival Time
02:20PM
Duration
1h40
Departure days
Mon, Fri, Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
03:55PM
Arrival Time
05:30PM
Duration
1h35
Departure days
Mon, Fri, Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
04:15PM
Arrival Time
05:30PM
Duration
1h15
Departure days
Mon, Fri, Sun
Cheapest price
$31
Operator
Greyhound
Departure Time
07:35PM
Arrival Time
09:20PM
Duration
1h45
Departure days
Mon, Fri, Sun
Cheapest price
$31

Live departures

Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA bus times

The table below shows live departures for Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA buses for today, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 2:47 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus7:55 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
2h25
10:20 PM Irvine, West Peltason Dr (UCI Crawford Hall), CA0 transfersDirect
meinfernbus_flixbusFlixBus7:55 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA
2h50
10:45 PM Anaheim, Regional Transportation Intermodal Center (ARTIC)0 transfersDirect
meinfernbus_flixbusFlixBus8:15 PM San Diego, Congress Street (Old Town Park), CA
2h30
10:45 PM Anaheim, Regional Transportation Intermodal Center (ARTIC)0 transfersDirect
meinfernbus_flixbusFlixBus8:15 PM San Diego, Congress Street (Old Town Park), CA
2h05
10:20 PM Irvine, West Peltason Dr (UCI Crawford Hall), CA0 transfersDirect
meinfernbus_flixbusFlixBus8:40 PM La Jolla, UCSD Health La Jolla Station, CA
1h40
10:20 PM Irvine, West Peltason Dr (UCI Crawford Hall), CA0 transfersDirect
meinfernbus_flixbusFlixBus8:40 PM La Jolla, UCSD Health La Jolla Station, CA
2h05
10:45 PM Anaheim, Regional Transportation Intermodal Center (ARTIC)0 transfersDirect
meinfernbus_flixbusFlixBus11:55 PM San Diego, Congress Street (Old Town Park), CA
1h35
1:30 AM Irvine, West Peltason Dr (UCI Crawford Hall), CA0 transfersDirect
Monday, December 22
meinfernbus_flixbusFlixBus12:15 AM La Jolla, UCSD Health La Jolla Station, CA
1h15
1:30 AM Irvine, West Peltason Dr (UCI Crawford Hall), CA0 transfersDirect
greyhound3:35 AM San Diego, Congress Street (Old Town Park), CA
1h45
5:20 AM Santa Ana, E Santa Ana Blvd (Train Station)0 transfersDirect
greyhound3:35 AM San Diego, Congress Street (Old Town Park), CA
2h00
5:35 AM Anaheim, Regional Transportation Intermodal Center (ARTIC)0 transfersDirect
greyhound2:45 PM San Diego, Congress Street (Old Town Park), CA
1h55
4:40 PM Santa Ana, E Santa Ana Blvd (Train Station)0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Dec 22
Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
Sat
Dec 27
Sun
Dec 28

Journey information

Overview: Bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA

USAUSA
USAUSA
Icon of bus

Buses from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA run on average 8 times per day, taking around 2h 7m. Cheap bus tickets for this journey start at $19 (€15) if you book in advance.

There are 7 buses per day. The earliest bus runs at 13:45, the last at 23:15. The fastest bus covers the 72 miles (117 km) distance in 1h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
72 miles (117 km)
Average bus duration
2h 7m
Cheapest ticket price
$19 (€15)
Buses per day
8
Direct buses
7
Fastest bus
1h 40m
First bus
13:45
Last bus
23:15
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CAYou can travel by bus between Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA with FlixBus, Greyhound for as low as $19 (€15). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
1h 40m
Cheapest Price
$19 (€15)
FlixBus frequency
11 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
1h 55m
Cheapest Price
$22 (€18)
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA

Find answers to the most common questions about traveling from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Irvine Transportation Center, Irvine, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA can start from as little as $24 (€19) when you book in advance. The average bus ticket price for Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA is $28 (€22); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA is 1 h 40 min   to travel the 72 mile (116 km) long trip, with around there are 11 buses per day. Journey times can vary on weekends and holidays.
The first bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA leaves at 1: 35PM. Plan your trip with the Journey Planner   from Omio.
The last bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA leaves at 8: 50PM.
Yes, it is possible to travel from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA without having to change trains with Greyhound. There are 10 direct buses from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA each day. There may be fewer direct services available on weekends or holidays.
When taking a bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA, you can count on FlixBus or Greyhound for the best way to get you to Irvine Transportation Center, Irvine, CA. You can also check all possible bus providers who offer a service to Irvine Transportation Center, Irvine, CA from Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
A day trip to Irvine Transportation Center, Irvine, CA from Santa Fe Depot, San Diego, CA is worth doing with a journey time of 1 h 40 min each way. Check with Omio app   the best way to travel.
The cheapest month to travel from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA by bus is September.
It's helpful to compare your options as there are 2 ways to travel from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA including taking a bus or train.
Yes, the following accessibility options are available when taking the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA for bus providers FlixBus and Greyhound.
Yes, bikes are allowed on board the bus with bus companies FlixBus and Greyhound.
Whether you can cancel your bus ticket from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA.
    Yes, the following luggage options are included when booking a bus ticket from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Greyhound
      • $15 per additional bag.
    Yes, you can bring your pet on the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA with the following bus providers: FlixBus and Greyhound
    Yes, there are USB plugs on board the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA with the following bus providers: FlixBus and Greyhound.
    Yes, there is Wifi on board the bus from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA with the following bus providers: FlixBus and Greyhound.

    More options for your journey from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA

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