1,000+ travel companies
1,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
Journey information
Overview: Bus from Depew, NY to Chicago, IL
USAUSA
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 462 miles (745 km) |
Buses per day 3 |
First bus 06:55 |
Last bus 23:15 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
FAQs: Bus from Depew, NY to Chicago, IL
Find answers to the most common questions about traveling from Depew, NY to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Depew, NY to Chicago, IL can start from as little as $99 (€81) when you book in advance. The average bus ticket price for Depew, NY to Chicago, IL is $112 (€91); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Depew, NY to Chicago, IL bus travel time is 13 h 10 min for the 461 mile (744 km) long journey, but the duration can vary if you travel on weekends and holidays.
The first bus from Depew, NY to Chicago, IL leaves at 1: 45AM. Plan your trip with the Journey Planner from Omio.
The last bus from Depew, NY to Chicago, IL leaves at 11: 15PM.
The cheapest month for a bus from Depew, NY to Chicago, IL is October.
You have options as you can travel between Depew, NY and Chicago, IL 3 different ways: bus, train or flight.
No, the bus from Depew, NY to Chicago, IL has no accessibility options.
No, there are no bathrooms on board the bus from Depew, NY to Chicago, IL.
Some of the most interesting sights to explore in Chicago, IL are:
- Millennium Park, a public park known for its modern art installations and the iconic Cloud Gate sculpture
- Art Institute of Chicago, a renowned museum housing an extensive collection of art from around the world
- Navy Pier, a popular entertainment destination featuring rides, restaurants, and lakefront views
- Willis Tower Skydeck, an observation deck offering panoramic views of the city from one of the tallest buildings in the Western Hemisphere
- Field Museum, a natural history museum with vast exhibits including the famous T. Rex skeleton, Sue.
The best things to do in Chicago, IL include:
- Museum of Science and Industry, an interactive museum featuring exhibits on science, technology, and industry
- Explore the vibrant neighborhoods of Chicago, such as Wicker Park and Lincoln Park, known for their unique shops and eateries
- Take a river cruise to see the city's iconic architecture from a different perspective
- Attend a live performance at the historic Chicago Theatre
- Enjoy a day at Lincoln Park Zoo, one of the oldest zoos in the U. S. Offering free admission.
No, bikes are not allowed on board the bus from Depew, NY to Chicago, IL.
To find the cheapest bus tickets for your trip from Depew, NY to Chicago, IL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Depew, NY to Chicago, IL.
No, luggage for the bus from Depew, NY to Chicago, IL needs to be booked in addition.
No, there are no additional luggage options for the bus from Depew, NY to Chicago, IL.
Unfortunately, pets are not allowed on the bus from Depew, NY to Chicago, IL.
No, there are no USB plugs on board the bus from Depew, NY to Chicago, IL.
No, there is no WiFi on board the bus from Depew, NY to Chicago, IL.
popular bus stations
Popular bus stations from Depew, NY to Chicago, IL
Depew
Chicago
Chicago, Greyhound Bus Station
information
Chicago, Union Station (Amtrak)
information
More options for your journey from Depew, NY to Chicago, IL
Here are some other resources that might have the information you need
Most popular buses to and from Chicago, IL and Depew, NY
Most popular bus connections to Chicago, IL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
