Chicago, IL to Depew, NY bus

Tue, Aug 04
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Chicago, IL to Depew, NY

Showing times and prices for Aug 05

Cheapest price

$57

Average price

$65

Fastest journey

13 h

Average duration

17 h 8 m

Buses per day

2

Distance

745 km

Cheap tickets

The best way to find a cheap bus ticket from Chicago, IL to Depew, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Chicago, IL to Depew, NY will cost around $65 if you buy it on the day, but the cheapest tickets can be found for only $57.

Fast buses

Of the 2 buses that leave Chicago, IL for Depew, NY on Wed, Aug 05, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Wed, Aug 05 the direct buses cover the 745 km distance in an average of 17 h 8 m but if you time it right, some buses will get you there in just 13 h .

On Wed, Aug 05 the slowest buses will take 21 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    12:00 AM21h15
    Chicago, IL
    9:15 PMDepew, NY
    $571One-way
    0 transfers
  • Greyhound
    11:00 PM13h00
    Chicago, IL
    12:00 PMDepew, NY
    $721One-way
    0 transfers

Journey information

Overview: Bus from Chicago, IL to Depew, NY

USAUSA
USAUSA
Icon of bus

Buses from Chicago, IL to Depew, NY run on average 2 times per day, taking around 18h 31m. Cheap bus tickets for this journey start at $57 if you book in advance.

The earliest bus runs at 06:55, the last at 23:15. The fastest bus covers the 462 miles (745 km) distance in 13h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
462 miles (745 km)
Average bus duration
18h 31m
Cheapest ticket price
$57
Buses per day
2
Fastest bus
13h 0m
First bus
6:55 AM
Last bus
11:15 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Jul - Sep
Best time to book
42 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Chicago, IL to Depew, NY Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:00AM
Arrival Time
09:15PM
Duration
21h15
Departure days
Wed
Cheapest price
$57
Operator
FlixBus
Departure Time
12:15AM
Arrival Time
08:15PM
Duration
20h00
Departure days
Thu, Sat, Sun
Cheapest price
$58
Operator
FlixBus
Departure Time
01:15AM
Arrival Time
09:45PM
Duration
20h30
Departure days
Mon, Tue, Fri, Sat
Cheapest price
$57
Operator
Greyhound
Departure Time
11:00PM
Arrival Time
12:00PM
Duration
13h00
Departure days
Mon, Tue, Thu
Cheapest price
$72

Live departures

Chicago, IL to Depew, NY bus times

The table below shows live departures for Chicago, IL to Depew, NY buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound11:00 PM Chicago, IL
13h00
12:00 PM Depew, NY0 transfersDirect
Tuesday, August 4
Greyhound12:00 AM Chicago, IL
21h15
9:15 PM Depew, NY0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

FAQs: Bus from Chicago, IL to Depew, NY

Find answers to the most common questions about traveling from Chicago, IL to Depew, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Depew, NY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Chicago, IL to Depew, NY can start from as little as $57 when you book in advance. The average bus ticket price for Chicago, IL to Depew, NY is $84 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Chicago, IL to Depew, NY is 13h 0m to travel the 462 miles (745 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Chicago, IL to Depew, NY leaves at 6:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to Depew, NY leaves at 11:15 PM.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and Depew, NY including taking a bus, train, and flight.
No, there are no bathrooms on board the bus from Chicago, IL to Depew, NY.
No, the bus from Chicago, IL to Depew, NY has no accessibility options.
No, bikes are not allowed on board the bus from Chicago, IL to Depew, NY.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Chicago, IL to Depew, NY.
No, luggage for the bus from Chicago, IL to Depew, NY needs to be booked in addition.
No, there are no additional luggage options for the bus from Chicago, IL to Depew, NY.
Unfortunately, pets are not allowed on the bus from Chicago, IL to Depew, NY.
No, there are no USB plugs on board the bus from Chicago, IL to Depew, NY.
No, there is no WiFi on board the bus from Chicago, IL to Depew, NY.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Depew, NY, travelers should be aware of common urban safety concerns such as petty theft and occasional vehicle break-ins, especially in parking areas near transit hubs. It's advisable to stay vigilant in crowded places and avoid poorly lit or isolated areas at night. While there are no widespread specific scams targeting travelers, standard precautions against phishing and overcharging when using local services are recommended.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Chicago, IL to Depew, NY

Most Chicago, IL to Depew, NY buses use the Chicago, Greyhound Bus Station to Buffalo, NFTA Metro Center station pair. Use this guide to compare Chicago, IL and Depew, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Chicago
Arrival bus stations in Depew
Chicago, Greyhound Bus Station
City-centre transport

Getting to Chicago, Greyhound Bus Station from Chicago city centre

Bus7 · 8m · $4 · every ~6 min
Chicago, Union Station (Amtrak)
City-centre transport

Getting to Chicago, Union Station (Amtrak) from Chicago city centre

Bus28, 151 · 7m · $4 · every ~13 min

More options for your journey from Chicago, IL to Depew, NY

Here are some other resources that might have the information you need

Return journeys for buses from Depew, NY to Chicago, IL
Flights from Chicago, IL to Depew, NY
Tickets and more information for coaches to Chicago, IL

Most popular buses to and from Depew, NY and Chicago, IL

Bus Chicago, IL - Boston, MA
Bus Chicago, IL - New York, NY
Bus Chicago, IL - Los Angeles, CA
Bus Chicago, IL - Washington, DC
Bus Chicago, IL - Las Vegas, NV
Bus Chicago, IL - San Diego, CA
Bus Chicago, IL - Philadelphia, PA
Bus Chicago, IL - Seattle, WA
Bus Chicago, IL - Salt Lake City, UT
Bus Chicago, IL - Orlando, FL
Bus Chicago, IL - Dallas, TX
Bus Chicago, IL - Atlanta, GA
Bus Chicago, IL - Miami, FL
Bus Chicago, IL - Portland, OR
Bus Chicago, IL - Phoenix, AZ
Bus Chicago, IL - Tampa, FL
Bus Chicago, IL - San Francisco, CA
Bus Chicago, IL - Sacramento, CA
Bus Chicago, IL - Houston, TX
Bus Chicago, IL - San Antonio, TX
Bus Chicago, IL - Denver, CO
Bus Chicago, IL - Newark, NJ
Bus New York, NY - Depew, NY
Bus Toronto, ON - Depew, NY
Bus Syracuse, NY - Depew, NY
Bus Rochester, NY - Depew, NY
Bus Detroit, MI - Depew, NY
Bus Cleveland, OH - Depew, NY
Bus Hartford, CT - Depew, NY
Bus Toledo, OH - Depew, NY
Bus Springfield, MA - Depew, NY
Bus Erie, PA - Depew, NY
Bus Rensselaer, NY - Depew, NY
HomeBusesBuses in USAChicago, IL to Depew, NY bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone