Chicago, IL to Depew, NY bus

Sat, Jun 20
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from Chicago, IL to Depew, NY

Showing times and prices for Jun 21

Cheapest price

$74

Average price

$74

Fastest journey

20 h

Average duration

20 h

Buses per day

1

Distance

745 km

Cheap tickets

The best way to find a cheap bus ticket from Chicago, IL to Depew, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Chicago, IL to Depew, NY will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $74.

Fast buses

Of the 1 buses that leave Chicago, IL for Depew, NY on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sun, Jun 21 the direct buses cover the 745 km distance in an average of 20 h but if you time it right, some buses will get you there in just 20 h .

On Sun, Jun 21 the slowest buses will take 20 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    12:15 AM20h00
    Chicago, IL
    8:15 PMDepew, NY
    $741One-way
    0 transfers

Travel Information

Compare bus, train, and flight for Chicago, IL to Depew, NY

Omio recommends booking the train as it is the most popular option from Chicago, IL to Depew, NY among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a flight which can get you there in 1h 55m. The ticket price range depends on the travel mode: a bus costs an average of $57, and a flight costs an average of $68.

Distance: 462 miles (745 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$84

Average price

Cheapest

$120

Average price

$249

Average price

$108

Average price

(fuel + tolls)

19h 1m

Average total duration

18h 31m

Onboard

+

30m

Additional time*

10h 53m

Average total duration

10h 23m

Onboard

+

30m

Additional time*

4h 55m

Average total duration

Fastest

1h 55m

Onboard

+

3h 0m

Additional time*

7h 59m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Chicago, IL to Depew, NY is a bus with an average price of $84 (€69).

This is compared to other travel options from Chicago, IL to Depew, NY:

A bus is $36 (€29) less than a train for this route with tickets for a train from Chicago, IL to Depew, NY costing on average $120 (€98).

A bus is $166 (€136) less than a flight for this route with tickets for a flight from Chicago, IL to Depew, NY costing on average $249 (€204).

The fastest way to travel from Chicago, IL to Depew, NY is by flight with an average journey time of 1h 55m.

Other travel options to Depew, NY take longer:

Train takes on average 10h 23m.

Bus takes on average 18h 31m.

It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and Depew, NY including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Chicago, IL to Depew, NY among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Chicago, IL to Depew, NY Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
12:15AM
Arrival Time
08:45PM
Duration
20h30
Departure days
Sat, Sun
Cheapest price
$74
Operator
FlixBus
Departure Time
01:15AM
Arrival Time
09:45PM
Duration
20h30
Departure days
Mon, Tue, Fri, Sat
Cheapest price
$57
Operator
Greyhound
Departure Time
10:15AM
Arrival Time
08:00AM
Duration
20h45
Departure days
Tue, Wed
Cheapest price
$67
Operator
Greyhound
Departure Time
06:00PM
Arrival Time
08:00AM
Duration
13h00
Departure days
Tue, Wed
Cheapest price
$63
Operator
FlixBus
Departure Time
07:15PM
Arrival Time
04:45PM
Duration
20h30
Departure days
Tue, Wed
Cheapest price
$63
Operator
Greyhound
Departure Time
11:00PM
Arrival Time
12:00PM
Duration
13h00
Departure days
Mon, Thu
Cheapest price
$84

Live departures

Chicago, IL to Depew, NY bus times

The table below shows live departures for Chicago, IL to Depew, NY buses for tomorrow, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBus12:15 AM Chicago, IL
20h00
8:15 PM Depew, NY0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Chicago, IL to Depew, NY by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Jun 20
Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26

Journey information

Overview: Bus from Chicago, IL to Depew, NY

USAUSA
USAUSA
Icon of bus

Buses from Chicago, IL to Depew, NY run on average 2 times per day, taking around 18h 31m. Cheap bus tickets for this journey start at $57 (€46) if you book in advance.

The earliest bus runs at 06:55, the last at 23:15. The fastest bus covers the 462 miles (745 km) distance in 13h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
462 miles (745 km)
Average bus duration
18h 31m
Cheapest ticket price
$57 (€46)
Buses per day
2
Fastest bus
13h 0m
First bus
6:55 AM
Last bus
11:15 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Jul - Sep
Best time to book
42 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Chicago, IL to Depew, NY

Find answers to the most common questions about traveling from Chicago, IL to Depew, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Depew, NY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Chicago, IL to Depew, NY can start from as little as $57 (€46) when you book in advance. The average bus ticket price for Chicago, IL to Depew, NY is $84 (€69) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Chicago, IL to Depew, NY is 13h 0m to travel the 462 miles (745 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Chicago, IL to Depew, NY leaves at 6:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Chicago, IL to Depew, NY leaves at 11:15 PM.
A trip to Depew, NY from Chicago, IL is worth doing but not as a day trip with a journey time of 13h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Chicago, IL to Depew, NY is February.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and Depew, NY including taking a bus, train, and flight.
No, the bus from Chicago, IL to Depew, NY has no accessibility options.
No, there are no bathrooms on board the bus from Chicago, IL to Depew, NY.
No, bikes are not allowed on board the bus from Chicago, IL to Depew, NY.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Chicago, IL to Depew, NY.
No, luggage for the bus from Chicago, IL to Depew, NY needs to be booked in addition.
No, there are no additional luggage options for the bus from Chicago, IL to Depew, NY.
Unfortunately, pets are not allowed on the bus from Chicago, IL to Depew, NY.
No, there are no USB plugs on board the bus from Chicago, IL to Depew, NY.
No, there is no WiFi on board the bus from Chicago, IL to Depew, NY.
Since neither Chicago, IL nor Depew, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Chicago, IL to Depew, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Depew, NY, travelers should be aware of common urban safety concerns such as petty theft and occasional vehicle break-ins, especially in parking areas near transit hubs. It's advisable to stay vigilant in crowded places and avoid poorly lit or isolated areas at night. While there are no widespread specific scams targeting travelers, standard precautions against phishing and overcharging when using local services are recommended.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Chicago, IL to Depew, NY

Most Chicago, IL to Depew, NY buses use the Chicago, Greyhound Bus Station to Buffalo, NFTA Metro Center station pair. Use this guide to compare Chicago, IL and Depew, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Chicago
Arrival bus stations in Depew
Chicago, Greyhound Bus Station
City-centre transport

Getting to Chicago, Greyhound Bus Station from Chicago city centre

Bus7 · 8m · $4 · every ~6 min
Chicago, Union Station (Amtrak)
City-centre transport

Getting to Chicago, Union Station (Amtrak) from Chicago city centre

Bus28, 151 · 7m · $4 · every ~13 min

More options for your journey from Chicago, IL to Depew, NY

Here are some other resources that might have the information you need

HomeBusesBuses in USAChicago, IL to Depew, NY bus

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