The cheapest and fastest buses from Chicago, IL to Depew, NY
Cheapest price
$78
Average price
$78
Fastest journey
21 h 15 m
Average duration
21 h 15 m
Buses per day
1
Distance
745 km
The best way to find a cheap bus ticket from Chicago, IL to Depew, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Depew, NY will cost around $78 if you buy it on the day, but the cheapest tickets can be found for only $78.
Of the 1 buses that leave Chicago, IL for Depew, NY on Thu, May 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 07 the direct buses cover the 745 km distance in an average of 21 h 15 m but if you time it right, some buses will get you there in just 21 h 15 m .
On Thu, May 07 the slowest buses will take 21 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:00 AM21h15Chicago, IL9:15 PMDepew, NY$781One-way0 transfers
12:00 AM21h15Chicago, IL9:15 PMDepew, NY$781One-way0 transfers
Travel Information
Compare bus, train, and flight for Chicago, IL to Depew, NY
Omio recommends booking the train as it is the most popular option from Chicago, IL to Depew, NY among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a flight which can get you there in 2h 14m. The ticket price range depends on the travel mode: a bus costs an average of $58, and a flight costs an average of $70.
Distance: 462 miles (745 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$78 Average price Cheapest | $106 Average price | $174 Average price |
20h 53m Average total duration 20h 23m Onboard + 30m Additional time* | 10h 53m Average total duration 10h 23m Onboard + 30m Additional time* | 5h 14m Average total duration Fastest 2h 14m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Chicago, IL to Depew, NY bus times
The table below shows live departures for Chicago, IL to Depew, NY buses for tomorrow, Wednesday, May 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:00 AM Chicago, IL | 21h15 | 9:15 PM Depew, NY | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Depew, NY by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 06
May 07
May 08
May 09
May 10
May 11
May 12
Journey information
Overview: Bus from Chicago, IL to Depew, NY
Buses from Chicago, IL to Depew, NY run on average 1 times per day, taking around 20h 23m. Cheap bus tickets for this journey start at $58 (€46) if you book in advance.
The earliest bus runs at 06:55, the last at 23:15. The fastest bus covers the 462 miles (745 km) distance in 20h 0m.
Distance 462 miles (745 km) |
Average bus duration 20h 23m |
Cheapest ticket price $58 (€46) |
Buses per day 1 |
Fastest bus 20h 0m |
First bus 6:55 AM |
Last bus 11:15 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Best time to book 42 days |
FAQs: Bus from Chicago, IL to Depew, NY
Find answers to the most common questions about traveling from Chicago, IL to Depew, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Depew, NY, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Chicago, IL to Depew, NY
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Depew, NY
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