Depew, NY to Cleveland, OH bus with Greyhound

Sun, Sep 20
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Avanza
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Depew, NY to Cleveland, OH

Showing times, prices and bookable tickets for Sep 20

Cheapest price on Sep 20

$32

Average ticket price on Sep 20

$33

Fastest journey on Sep 20

3 h 50 m

Average journey duration on Sep 20

3 h 50 m

Buses on Sep 20

2

Distance

293 km

Cheap tickets

The best way to find a cheap bus ticket from Depew, NY to Cleveland, OH is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Depew, NY to Cleveland, OH will cost around $33 if you buy it on the day, but the cheapest tickets can be found for only $32.

Fast buses

On Sun, Sep 20, we found 2 buses from Depew, NY to Cleveland, OH, including 2 direct services.

On Sun, Sep 20 the direct buses cover the 293 km distance in an average of 3 h 50 m but if you time it right, some buses will get you there in just 3 h 50 m .

On Sun, Sep 20 the slowest buses will take 3 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    11:55 AM3h50
    Depew, NY
    3:45 PMCleveland, OH
    $321One-way
    0 transfers
  • Greyhound
    12:55 PM3h50
    Depew, NY
    4:45 PMCleveland, OH
    $341One-way
    0 transfers

Travel Information

Compare bus, train, and flight for Depew, NY to Cleveland, OH

Omio recommends booking the train as it is the most popular option from Depew, NY to Cleveland, OH among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $40 For those with little time, consider booking a train, which has an average total journey time of 3h 44m. Average ticket prices depend on the travel mode: a bus costs an average of $40, while a flight costs an average of $661.

Distance: 182 miles (293 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$40

Average price

Cheapest

$65

Average price

$661

Average price

$41

Average price

(fuel + tolls)

4h 10m

Average total duration

3h 40m

Onboard

+

30m

Additional time*

3h 44m

Average total duration

Fastest

3h 14m

Onboard

+

30m

Additional time*

5h 25m

Average total duration

3h 25m

Onboard

+

2h 0m

Additional time*

2h 58m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Amtrak

Most popular train company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Depew, NY to Cleveland, OH is a bus with an average price of $40.

This is compared to other travel options from Depew, NY to Cleveland, OH:

A bus is $25 less than a train for this route with tickets for a train from Depew, NY to Cleveland, OH costing on average $65.

A bus is $621 less than a flight for this route with tickets for a flight from Depew, NY to Cleveland, OH costing on average $661.

The fastest way to travel from Depew, NY to Cleveland, OH is by train with an average journey time of 3h 14m.

Other travel options to Cleveland, OH take longer:

Flight takes on average 3h 25m.

Bus takes on average 3h 40m.

It's helpful to compare your options as there are 3 ways to travel between Depew, NY and Cleveland, OH including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Depew, NY to Cleveland, OH among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $40 compared to roughly $41 in fuel and tolls — a saving of about $0.77. The journey takes 3h 40m versus 2h 58m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Depew, NY to Cleveland, OH Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
11:55AM
Arrival Time
03:45PM
Duration
3h50
Departure days
Mon, Sun
Cheapest price
$32
Operator
Greyhound
Departure Time
12:55PM
Arrival Time
04:35PM
Duration
3h40
Departure days
Thu, Sun
Cheapest price
$26

Compare prices and tickets Depew, NY to Cleveland, OH by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25
Sat
Sep 26

Journey information

Overview: Bus from Depew, NY to Cleveland, OH

USAUSA
USAUSA
Icon of bus

Buses from Depew, NY to Cleveland, OH run on average 1 times per day, taking around 3h 40m. Cheap bus tickets for this journey start at $32 but you can travel from only $28 by train.

There are 1 buses per day. The earliest bus runs at 07:55, the last at 22:45. The fastest bus covers the 182 miles (293 km) distance in 3h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $28
Distance
182 miles (293 km)
Average bus duration
3h 40m
Cheapest ticket price
$32
Buses per day
1
Direct buses
1
Fastest bus
3h 40m
First bus
7:55 AM
Last bus
10:45 PM
Cheapest Month
Feb
Cheapest Day
Thu
High Season
Jul - Sep
Low Season
Apr - Jun
Best time to book
6 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $28

Complete guide to Cleveland, OH

Things to do in Cleveland, OH

Discover the best of Cleveland, OH — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Cleveland, OH trip today.

  • Must visit

Cleveland Museum of Art

World-class art museum famed for encyclopedic collections, free general admission, and standout holdings from ancient to contemporary art.

  • Must visit

Rock and Roll Hall of Fame

Major music museum celebrating rock history with iconic artifacts, immersive exhibits, and strong appeal for first-time visitors.

  • Recommended

Great Lakes Science Center

Excellent science museum with hands-on exhibits, a planetarium, and family-friendly learning in a restored historic mansion setting.

United States dollar ($)

Moderate for U.S. city travel: hotels and dining are usually cheaper than New York or Chicago, while transit and attractions are generally manageable for visitors.

Average meal costs

Budget
$10-15 for fast food or casual spots.
Mid-range
$20-35 per person for a restaurant meal.
Fine dining
$60+ per person at upscale restaurants.
Coffee
$3-5 for coffee or cappuccino.

Tipping culture

Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or coffee in cafes if service is good.

FAQs: Bus from Depew, NY to Cleveland, OH

Find answers to the most common questions about traveling from Depew, NY to Cleveland, OH by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Cleveland, OH, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Depew, NY to Cleveland, OH can start from as little as $32 when you book in advance. The average bus ticket price for Depew, NY to Cleveland, OH is $40 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Depew, NY to Cleveland, OH is 3h 40m to travel the 182 miles (293 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Depew, NY to Cleveland, OH leaves at 7:55 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Depew, NY to Cleveland, OH leaves at 10:45 PM.
When departing from Depew, NY , you have various bus station options to start your journey from including Buffalo, NFTA Metro Center . When arriving in Cleveland, OH , you can end your journey in bus stations like Cleveland, Chester Ave At the Greyhound Station (South Side), Cleveland, Cleveland Bus Station (Brook Park), OH .Passengers board the bus most frequently from Buffalo, NFTA Metro Center, which is located around away from the city centre, and they get off the bus at Cleveland, Chester Ave At the Greyhound Station (South Side), located 1 away from the city centre.
A trip to Cleveland, OH from Depew, NY is worth doing but not as a day trip with a journey time of 3h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Depew, NY to Cleveland, OH is February.
It's helpful to compare your options as there are 3 ways to travel between Depew, NY and Cleveland, OH including taking a bus, train, and flight.
No, the bus from Depew, NY to Cleveland, OH has no accessibility options.
No, there are no bathrooms on board the bus from Depew, NY to Cleveland, OH.
No, bikes are not allowed on board the bus from Depew, NY to Cleveland, OH.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Depew, NY to Cleveland, OH.
No, luggage for the bus from Depew, NY to Cleveland, OH needs to be booked in addition.
No, there are no additional luggage options for the bus from Depew, NY to Cleveland, OH.
Unfortunately, pets are not allowed on the bus from Depew, NY to Cleveland, OH.
No, there are no USB plugs on board the bus from Depew, NY to Cleveland, OH.
No, there is no WiFi on board the bus from Depew, NY to Cleveland, OH.
Since neither Depew, NY nor Cleveland, OH are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Depew, NY to Cleveland, OH among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Cleveland, OH, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular attractions. Avoid poorly lit or isolated neighborhoods at night. Common scams include fake ticket sellers near sports venues and overcharging by unlicensed taxi or rideshare drivers. Staying alert and using official transportation options enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Depew, NY to Cleveland, OH

Most Depew, NY to Cleveland, OH buses use the Buffalo, NFTA Metro Center to Cleveland, Chester Ave At the Greyhound Station (South Side) station pair. Use this guide to compare Depew, NY and Cleveland, OH bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Depew
Arrival bus stations in Cleveland

Which Cleveland, OH station do buses from Depew, NY arrive at?

Buses from Depew, NY to Cleveland, OH most often arrive at Cleveland, Chester Ave At the Greyhound Station (South Side). Some services arrive at Cleveland, Cleveland Bus Station (Brook Park), so check your ticket before travel to confirm your Cleveland, OH arrival station.
Cleveland, Chester Ave At the Greyhound Station (South Side)Cleveland, Cleveland, OH 44114, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Cleveland, Chester Ave At the Greyhound Station (South Side) from Cleveland city centre

Cleveland, Chester Ave At the Greyhound Station (South Side) is 1 km from Cleveland city centre. Public transport options include:

BusHl · 15m · $4 · every ~10 min
Hl · 16m · $4 · every ~10 min

Cleveland, Chester Ave At the Greyhound Station (South Side) bus station facilities and services

Cleveland, Chester Ave At the Greyhound Station (South Side) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Snack bar available onsite.

Wi-Fi and ATMs

Free WiFi available for passengers. ATMs are available at Cleveland, Chester Ave At the Greyhound Station (South Side).

Tickets and information

Ticket office support is available at Cleveland, Chester Ave At the Greyhound Station (South Side).

Parking, taxis and toilets

Available at Cleveland, Chester Ave At the Greyhound Station (South Side): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Cleveland, Chester Ave At the Greyhound Station (South Side): Station is wheelchair accessible.

More options for your journey from Depew, NY to Cleveland, OH

Here are some other resources that might have the information you need

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone