Travel Information
Compare train, bus, and flight for Würzburg to Prague
Omio recommends booking the bus as it is the most popular option from Würzburg to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $40 For those with little time, consider booking a flight, which has an average total journey time of 4h 51m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $40, while a flight costs an average of $418.
Distance: 200 miles (323 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$40 Average price Cheapest | $62 Average price | $418 Average price | $77 Average price (fuel + tolls) |
6h 25m Average total duration 5h 55m Onboard + 30m Additional time* | 6h 10m Average total duration 5h 40m Onboard + 30m Additional time* | 4h 51m Average total duration Fastest 2h 51m Onboard + 2h 0m Additional time* | 4h 27m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 1.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Würzburg to Prague
Compare the available ways to get from Würzburg to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Würzburg to Prague:
A bus is $23 less than a train for this route with tickets for a train from Würzburg to Prague costing on average $62.
A bus is $379 less than a flight for this route with tickets for a flight from Würzburg to Prague costing on average $418.
Other travel options to Prague take longer:
Train takes on average 6h 10m.
Bus takes on average 6h 25m.
Tickets start at around $40 compared to roughly $77 in fuel and tolls — a saving of about $38. The journey takes 5h 55m versus 4h 27m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Würzburg to Prague
How to get from Würzburg to Prague by train, bus or flight.
Our recommendation
The best way to travel from Würzburg to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus1:35 AM 5h20 Würzburg, Hbf 6:55 AM Praha, ÚAN Florenc $30 1 One-way 0 transfers
Cheapest
FlixBus1:35 AM 5h20 Würzburg, Hbf 6:55 AM Praha, ÚAN Florenc $30 1 One-way 0 transfers
Fastest
DE44842:30 PM 1h00 Frankfurt am Main Airport 3:30 PM Prague Vaclav Havel Airport $179 1 One-way 0 transfers
Other options
ICE 583 · 3565 · Bus RE25 · EX 35710:29 AM 5h52 Würzburg Hbf 4:21 PM Prague hlavní nádraží $40 1 One-way 3 transfers
ICE 581 · 3561 · Bus RE25 · EX 3558:29 AM 5h52 Würzburg Hbf 2:21 PM Prague hlavní nádraží $40 1 One-way 3 transfers
ICE 585 · 3569 · Bus RE25 · EX 35912:29 PM 5h52 Würzburg Hbf 6:21 PM Prague hlavní nádraží $40 1 One-way 3 transfers
FlixBus3:25 PM 5h45 Würzburg, Hbf 9:10 PM Praha, Na Knížecí $30 1 One-way 0 transfers
FlixBus3:25 PM 6h05 Würzburg, Hbf 9:30 PM Praha, ÚAN Florenc $30 1 One-way 0 transfers
FlixBus1:00 PM 6h10 Würzburg, Hbf 7:10 PM Praha, Na Knížecí $35 1 One-way 0 transfers
DE44829:55 AM 1h00 Frankfurt am Main Airport 10:55 AM Prague Vaclav Havel Airport $193 1 One-way 0 transfers
ICE 822+
DE44846:55 AM 8h35 Würzburg Hbf 3:30 PM Prague Vaclav Havel Airport $204 1 One-way 1 transfer
ICE 1020+
DE44848:24 AM 7h06 Würzburg Hbf 3:30 PM Prague Vaclav Havel Airport $205 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Würzburg to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Würzburg to Prague.

This is compared to other travel options from Würzburg to Prague:
A bus is $23 less than a train for this route with tickets for a train from Würzburg to Prague costing on average $62.
A bus is $379 less than a flight for this route with tickets for a flight from Würzburg to Prague costing on average $418.
Other travel options to Prague take longer:
Train takes on average 6h 10m.
Bus takes on average 6h 25m.
- Around 59 flights per day.
- Around 20 trains per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Würzburg and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Würzburg Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Würzburg, Hbf and arrive in Praha, ÚAN Florenc.
- Travel with Lufthansa, KLM, Lot Polish Airlines, Turkish Airlines, Condor Flugdienst, Austrian Airlines, British Airways, Air Dolomiti, KLM Cityhopper, Qatar Airways, Swiss, Air Baltic, Brussels Airlines, Lufthansa Cityline, CitizenPlane, Helvetic Airways, Edelweiss Air to go to Prague by flight.
- Travel with FlixBus, Infobus to go to Prague by bus.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, České dráhy, Deutsche Bahn to go to Prague by train.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti, CitizenPlane.
- 7 direct buses per day with FlixBus, Infobus.
Travelling from Würzburg to Prague: related information
Here are some other resources that might have the information you need


