Travel Information
Compare bus and flight for Santander to Milan
Omio recommends booking the flight as it is the most popular option from Santander to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč 1,494 For those with little time, consider booking a flight, which has an average total journey time of 5h 25m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.1 - 2.6kg. Average ticket prices depend on the travel mode: a bus costs an average of Kč 1,494, while a flight costs an average of Kč 9,458.
Distance: 654 miles (1054 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
Kč 9,458 Average price | Kč 1,494 Average price Cheapest | Kč 5,833 Average price (fuel + tolls) |
5h 25m Average total duration Fastest 3h 25m Onboard + 2h 0m Additional time* | 22h 24m Average total duration 21h 54m Onboard + 30m Additional time* | 14h 19m Average total duration (door-to-door) |
3.2 - 6.3kg CO2 emissions | 1.1 - 2.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Santander to Milan
Compare the available ways to get from Santander to Milan, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Santander to Milan:
A bus is Kč 7,965 less than a flight for this route with tickets for a flight from Santander to Milan costing on average Kč 9,458.
Other travel options to Milan take longer:
Bus takes on average 22h 24m.
You'll arrive about 10h 54m sooner (3h 25m by flight vs 14h 19m by car). Tickets start at around Kč 9,458 compared to roughly Kč 5,833 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Santander to Milan
How to get from Santander to Milan by train, bus or flight.
Our recommendation
The best way to travel from Santander to Milan is by taking a flight because it’s the best combination of price and speed.
W463588:35 AM 1h55 Santander Airport 10:30 AM Milan Malpensa Airport Kč 1,849 1 One-way 0 transfers
Cheapest
W463588:35 AM 1h55 Santander Airport 10:30 AM Milan Malpensa Airport Kč 1,849 1 One-way 0 transfers
Fastest
W463588:35 AM 1h55 Santander Airport 10:30 AM Milan Malpensa Airport Kč 1,849 1 One-way 0 transfers
Other options
FlixBus · FlixBus · FlixBus9:25 AM 45h45 Santander, Estación de Autobuses 7:10 AM Milano, Autostazione Lampugnano Kč 4,813 1 One-way 2 transfers
04072+
IB8037:05 AM 15h05 Santander station 10:10 PM Milan Malpensa Airport Kč 3,723 1 One-way 1 transfer
04072+
IB6757:05 AM 11h20 Santander station 6:25 PM Milan Malpensa Airport Kč 5,181 1 One-way 1 transfer
VY1205 · VY605412:55 PM 8h45 Santander Airport 9:40 PM Milan Malpensa Airport Kč 5,848 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Santander to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Milan.

This is compared to other travel options from Santander to Milan:
A bus is Kč 7,965 less than a flight for this route with tickets for a flight from Santander to Milan costing on average Kč 9,458.
Other travel options to Milan take longer:
Bus takes on average 22h 24m.
- Around 10 flights per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Santander and Milan as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Milan Malpensa Airport.
- Buses mostly depart from Santander, Estación de Autobuses and arrive in Milano, Autostazione Lampugnano.
- Travel with Iberia, Vueling, British Airways, easyJet to go to Milan by flight.
- Travel with BlaBlaCar Bus, FlixBus to go to Milan by bus.
- 0 direct flights per day with easyJet.
Travelling from Santander to Milan: related information
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