Travel Information
Compare bus and flight for Santander to Milan
Omio recommends booking the flight as it is the most popular option from Santander to Milan among Omio's users. If you are prioritising price take the bus with prices starting from $92. For those with little time consider booking a flight which can get you there in 2h 34m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.1 - 2.6kg. The ticket price range depends on the travel mode: a bus costs an average of $92, and a flight costs an average of $61.
Distance: 654 miles (1054 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$277 Average price | $176 Average price Cheapest | $271 Average price (fuel + tolls) |
5h 34m Average total duration Fastest 2h 34m Onboard + 3h 0m Additional time* | 22h 31m Average total duration 22h 1m Onboard + 30m Additional time* | 14h 19m Average total duration (door-to-door) |
3.2 - 6.3kg CO2 emissions | 1.1 - 2.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santander to Milan:
A bus is $101 (€82) less than a flight for this route with tickets for a flight from Santander to Milan costing on average $277 (€226).
Other travel options to Milan take longer:
Bus takes on average 22h 1m.
Travel optionsfrom Santander to Milan
How to get from Santander to Milan by train, bus or flight.
Our recommendation
The best way to travel from Santander to Milan is by taking a flight because it’s the best combination of price and speed.
VY1597 · VY63366:35 PM4h30Santander Airport11:05 PMMilan Malpensa Airport$1531One-way1 transfer
Cheapest
VY1597 · VY63366:35 PM4h30Santander Airport11:05 PMMilan Malpensa Airport$1531One-way1 transfer
Fastest
VY1597 · VY63366:35 PM4h30Santander Airport11:05 PMMilan Malpensa Airport$1531One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus6:50 PM29h15Santander, Estación de Autobuses12:05 AMMilano, Autostazione Lampugnano$2291One-way2 transfers
04072+
W463146:48 AM12h37Santander station7:25 PMMilan Malpensa Airport$2661One-way1 transfer
04072+
UX10616:48 AM10h27Santander station5:15 PMMilan Malpensa Airport$2661One-way1 transfer
04072+
IB6676:48 AM16h12Santander station11:00 PMMilan Linate Airport$2691One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Santander to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Milan.

This is compared to other travel options from Santander to Milan:
A bus is $101 (€82) less than a flight for this route with tickets for a flight from Santander to Milan costing on average $277 (€226).
Other travel options to Milan take longer:
Bus takes on average 22h 1m.
- Around 10 flights per day.
- Around 1 buses per day.
However, we recommend checking specific travel dates for your route between Santander and Milan as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Milan Malpensa Airport.
- Buses mostly depart from Santander, Estación de Autobuses and arrive in Milano, Autostazione Lampugnano.
- Travel with Vueling, Ryanair, Iberia, Malta Air to go to Milan by flight.
- Travel with FlixBus to go to Milan by bus.
- 0 direct flights per day with Malta Air.
Travelling from Santander to Milan: related information
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