Travel Information
Compare bus and flight for Santander to Lisbon
Omio recommends booking the bus as it is the most popular option from Santander to Lisbon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $111 For those with little time, consider booking a flight, which has an average total journey time of 5h 29m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.7 - 1.7kg. Average ticket prices depend on the travel mode: a bus costs an average of $111, while a flight costs an average of $543.
Distance: 429 miles (691 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$111 Average price Cheapest | $543 Average price | $166 Average price (fuel + tolls) |
15h 33m Average total duration 15h 3m Onboard + 30m Additional time* | 5h 29m Average total duration Fastest 3h 29m Onboard + 2h 0m Additional time* | 8h 16m Average total duration (door-to-door) |
0.7 - 1.7kg CO2 emissions Lowest | 2.1 - 4.1kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Santander to Lisbon
Compare the available ways to get from Santander to Lisbon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Santander to Lisbon:
A bus is $432 (€363) less than a flight for this route with tickets for a flight from Santander to Lisbon costing on average $543 (€455).
Other travel options to Lisbon take longer:
Bus takes on average 15h 33m.
Tickets start at around $111 (€93) compared to roughly $166 (€140) in fuel and tolls — a saving of about $56 (€47). The journey takes 15h 3m versus 8h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Santander to Lisbon
How to get from Santander to Lisbon by train, bus or flight.
Our recommendation
The best way to travel from Santander to Lisbon is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus9:25 AM 14h35 Santander, Estación de Autobuses 11:00 PM Lisboa, Gare Oriente $80 1 One-way 1 transfer
Cheapest
FlixBus · FlixBus9:25 AM 14h35 Santander, Estación de Autobuses 11:00 PM Lisboa, Gare Oriente $80 1 One-way 1 transfer
Fastest
IB1064 · IB5375:40 PM 3h25 Santander Airport 8:05 PM Humberto Delgado Airport $325 1 One-way 1 transfer
Other options
FlixBus · FlixBus9:25 AM 14h50 Santander, Estación de Autobuses 11:15 PM Lisboa, Terminal Rodoviário de Sete Rios $81 1 One-way 1 transfer
04142+
U276461:55 PM 8h55 Santander station 9:50 PM Humberto Delgado Airport $205 1 One-way 1 transfer
04072+
U276467:05 AM 15h45 Santander station 9:50 PM Humberto Delgado Airport $219 1 One-way 1 transfer
04072+
IB5357:05 AM 12h00 Santander station 6:05 PM Humberto Delgado Airport $270 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Santander to Lisbon
Travel to Lisbon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Lisbon.

This is compared to other travel options from Santander to Lisbon:
A bus is $432 (€363) less than a flight for this route with tickets for a flight from Santander to Lisbon costing on average $543 (€455).
Other travel options to Lisbon take longer:
Bus takes on average 15h 33m.
- Around 8 flights per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Santander and Lisbon as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Humberto Delgado Airport.
- Buses mostly depart from Santander, Estación de Autobuses and arrive in Lisboa, Gare Oriente.
- Travel with Iberia, Vueling, British Airways, Ryanair to go to Lisbon by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Lisbon by bus.
Travelling from Santander to Lisbon: related information
Here are some other resources that might have the information you need
