Travel Information
Compare for Mannheim to Saint-Louis
Omio recommends booking the train as it is the most popular option from Mannheim to Saint-Louis among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $30 For those with little time, consider booking a train, which has an average total journey time of 3h 12m. Average ticket prices depend on the travel mode: a bus costs an average of $30, while a train costs an average of $65.
Distance: 138 miles (223 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$65 Average price | $30 Average price Cheapest | $42 Average price (fuel + tolls) |
3h 12m Average total duration Fastest 2h 42m Onboard + 30m Additional time* | 5h 40m Average total duration 5h 10m Onboard + 30m Additional time* | 2h 49m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Compare ways to travel from Mannheim to Saint-Louis
Compare the available ways to get from Mannheim to Saint-Louis, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Mannheim to Saint-Louis:
A bus is $36 less than a train for this route with tickets for a train from Mannheim to Saint-Louis costing on average $65.
Other travel options to Saint-Louis take longer:
Bus takes on average 5h 40m.
You'll arrive about 7m sooner (2h 42m by train vs 2h 49m by car). Tickets start at around $65 compared to roughly $42 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
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FAQs: Travel from Mannheim to Saint-Louis
Travel to Saint-Louis easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Saint-Louis.

This is compared to other travel options from Mannheim to Saint-Louis:
A bus is $36 less than a train for this route with tickets for a train from Mannheim to Saint-Louis costing on average $65.
Other travel options to Saint-Louis take longer:
Bus takes on average 5h 40m.
- Around 8 trains per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Mannheim and Saint-Louis as scheduled services by can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in EuroAirport Basel Mulhouse Freiburg.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Saint-Louis, EuroAirport Basel-Mulhouse-Freiburg.
- Trains mostly depart from Mannheim Hbf and arrive in Basel SBB.
- Travel with FlixBus to go to Saint-Louis by bus.
- Travel with Deutsche Bahn, TER, TGV, SNCF | TGV INOUI to go to Saint-Louis by train.
- 1 direct buses per day with FlixBus.
Travelling from Mannheim to Saint-Louis: related information
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