Travel Information
Compare bus and train for Frankfurt am Main to Saint-Louis
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Saint-Louis among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €37 For those with little time, consider booking a train, which has an average total journey time of 3h 51m. Average ticket prices depend on the travel mode: a bus costs an average of €37, while a flight costs an average of €517.
Distance: 182 miles (293 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
€517 Average price | €73 Average price | €37 Average price Cheapest | €35 Average price (fuel + tolls) |
5h 35m Average total duration 3h 35m Onboard + 2h 0m Additional time* | 3h 51m Average total duration Fastest 3h 21m Onboard + 30m Additional time* | 7h 40m Average total duration 7h 10m Onboard + 30m Additional time* | 3h 35m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Compare ways to travel from Frankfurt am Main to Saint-Louis
Compare the available ways to get from Frankfurt am Main to Saint-Louis, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Frankfurt am Main to Saint-Louis:
A bus is €37 less than a train for this route with tickets for a train from Frankfurt am Main to Saint-Louis costing on average €73.
A bus is €480 less than a flight for this route with tickets for a flight from Frankfurt am Main to Saint-Louis costing on average €517.
Other travel options to Saint-Louis take longer:
Flight takes on average 5h 35m.
Bus takes on average 7h 40m.
Tickets start at around €517 compared to roughly €35 in fuel and tolls — a saving of about -€481. The journey takes 3h 35m versus 3h 35m by car, so you may arrive a little later, but you can relax instead of spending the time behind the wheel.
Driving is worth considering if you're on a tight schedule, travelling as a group, or want the flexibility to stop along the way.
Compare prices and tickets Prices for trains, buses and flights
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Frankfurt am Main to Saint-Louis
Travel to Saint-Louis easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Saint-Louis.

This is compared to other travel options from Frankfurt am Main to Saint-Louis:
A bus is €37 less than a train for this route with tickets for a train from Frankfurt am Main to Saint-Louis costing on average €73.
A bus is €480 less than a flight for this route with tickets for a flight from Frankfurt am Main to Saint-Louis costing on average €517.
Other travel options to Saint-Louis take longer:
Flight takes on average 5h 35m.
Bus takes on average 7h 40m.
- Around 9 trains per day.
- Around 3 buses per day.
- Around 2 flights per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Saint-Louis as scheduled services by bus and train can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in EuroAirport Basel Mulhouse Freiburg.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Basel, EuroAirport.
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Saint-Louis, EuroAirport Basel-Mulhouse-Freiburg.
- Travel with FlixBus to go to Saint-Louis by bus.
- Travel with British Airways to go to Saint-Louis by flight.
- Travel with Deutsche Bahn, SNCF | TGV INOUI, TGV to go to Saint-Louis by train.
- 2 direct buses per day with FlixBus.
Travelling from Frankfurt am Main to Saint-Louis: related information
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