Travel Information
Compare train and bus for Lille to Prague
Omio recommends booking the bus as it is the most popular option from Lille to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $77 For those with little time, consider booking a train, which has an average total journey time of 11h 12m. Average ticket prices depend on the travel mode: a bus costs an average of $77, while a train costs an average of $399.
Distance: 501 miles (807 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$77 Average price Cheapest | $399 Average price | $204 Average price (fuel + tolls) |
17h 22m Average total duration 16h 52m Onboard + 30m Additional time* | 11h 12m Average total duration Fastest 10h 42m Onboard + 30m Additional time* | 10h 57m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lille to Prague:
A bus is $187 (€153) less than a train for this route with tickets for a train from Lille to Prague costing on average $298 (€244).
Other travel options to Prague take longer:
Bus takes on average 16h 58m.
Tickets start at around $298 (€244) compared to roughly $204 (€167) in fuel and tolls — a saving of about $-94.13 (€-76.93). The journey takes 12h 2m versus 10h 57m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Lille to Prague
How to get from Lille to Prague by train, bus or flight.
Our recommendation
The best way to travel from Lille to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus6:45 PM18h00Lille, Boulevard de Turin (Gare Lille Europe)12:45 PMPraha, Na Knížecí$951One-way1 transfer
Cheapest
FlixBus · FlixBus6:45 PM18h00Lille, Boulevard de Turin (Gare Lille Europe)12:45 PMPraha, Na Knížecí$951One-way1 transfer
Fastest
9832+
AF15823:47 PM5h58Lille-Europe9:45 PMPrague Vaclav Havel Airport$3211One-way1 transfer
Other options
FlixBus · FlixBus6:45 PM18h20Lille, Boulevard de Turin (Gare Lille Europe)1:05 PMPraha, ÚAN Florenc$951One-way1 transfer
FlixBus · FlixBus7:00 AM17h30Lille, Boulevard de Turin (Gare Lille Europe)12:30 AMPraha, Na Knížecí$971One-way1 transfer
FlixBus · FlixBus7:00 AM17h45Lille, Boulevard de Turin (Gare Lille Europe)12:45 AMPrague, Central Train Station$971One-way1 transfer
12526+
QS103710:56 AM11h04Lille-Europe10:00 PMPrague Vaclav Havel Airport$2361One-way1 transfer
12512+
QS10378:53 AM13h07Lille-Europe10:00 PMPrague Vaclav Havel Airport$2361One-way1 transfer
5224+
QS10379:36 AM12h24Lille Flandres10:00 PMPrague Vaclav Havel Airport$2391One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Lille to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lille to Prague.

This is compared to other travel options from Lille to Prague:
A bus is $187 (€153) less than a train for this route with tickets for a train from Lille to Prague costing on average $298 (€244).
Other travel options to Prague take longer:
Bus takes on average 16h 58m.
- Around 21 buses per day.
- Around 5 trains per day.
However, we recommend checking specific travel dates for your route between Lille and Prague as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Herseaux and arrive in Prague hlavní nádraží.
- Buses mostly depart from Lille, Boulevard de Turin (Gare Lille Europe) and arrive in Prague, Central Train Station.
- Travel with FlixBus, BlaBlaCar Bus to go to Prague by bus.
- Travel with Deutsche Bahn, SNCF | TGV INOUI to go to Prague by train.
- 2 direct buses per day with FlixBus.
Travelling from Lille to Prague: related information
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