Travel Information
Compare train and bus for Lille to Prague
Omio recommends booking the bus as it is the most popular option from Lille to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $101 For those with little time, consider booking a train, which has an average total journey time of 12h 31m. Average ticket prices depend on the travel mode: a bus costs an average of $101, while a train costs an average of $291.
Distance: 501 miles (807 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$101 Average price Cheapest | $291 Average price | $199 Average price (fuel + tolls) |
16h 51m Average total duration 16h 21m Onboard + 30m Additional time* | 12h 31m Average total duration Fastest 12h 1m Onboard + 30m Additional time* | 10h 57m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Compare ways to travel from Lille to Prague
Compare the available ways to get from Lille to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Lille to Prague:
A bus is $190 (€160) less than a train for this route with tickets for a train from Lille to Prague costing on average $291 (€244).
Other travel options to Prague take longer:
Bus takes on average 16h 51m.
Tickets start at around $101 (€85) compared to roughly $199 (€167) in fuel and tolls — a saving of about $99 (€83). The journey takes 16h 21m versus 10h 57m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Lille to Prague
How to get from Lille to Prague by train, bus or flight.
Our recommendation
The best way to travel from Lille to Prague is by taking a flight because it’s the best combination of price and speed.
U216499:35 AM 1h35 Lille Airport 11:10 AM Prague Vaclav Havel Airport $81 1 One-way 0 transfers
Cheapest
U216499:35 AM 1h35 Lille Airport 11:10 AM Prague Vaclav Havel Airport $81 1 One-way 0 transfers
Fastest
U216499:35 AM 1h35 Lille Airport 11:10 AM Prague Vaclav Havel Airport $81 1 One-way 0 transfers
Other options
9870+
QS10357:59 AM 8h46 Lille-Europe 4:45 PM Prague Vaclav Havel Airport $185 1 One-way 1 transfer
5224+
QS10359:36 AM 7h09 Lille Flandres 4:45 PM Prague Vaclav Havel Airport $189 1 One-way 1 transfer
5202+
QS10356:15 AM 10h30 Lille Flandres 4:45 PM Prague Vaclav Havel Airport $191 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lille to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lille to Prague.

This is compared to other travel options from Lille to Prague:
A bus is $190 (€160) less than a train for this route with tickets for a train from Lille to Prague costing on average $291 (€244).
Other travel options to Prague take longer:
Bus takes on average 16h 51m.
- Around 20 buses per day.
- Around 5 trains per day.
However, we recommend checking specific travel dates for your route between Lille and Prague as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Herseaux and arrive in Prague hlavní nádraží.
- Buses mostly depart from Lille, Boulevard de Turin (Gare Lille Europe) and arrive in Praha, ÚAN Florenc.
- Travel with České dráhy, Deutsche Bahn, Regional-Express to go to Prague by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Prague by bus.
- 2 direct buses per day with FlixBus.
Travelling from Lille to Prague: related information
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