Travel Information
Compare train, bus, and flight for Leverkusen to Prague
Omio recommends booking the train as it is the most popular option from Leverkusen to Prague among Omio's users. If you are prioritising price, take the train, with an average ticket price of $171 For those with little time, consider booking a flight, which has an average total journey time of 4h 37m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a train costs an average of $171, while a flight costs an average of $537.
Distance: 332 miles (535 km)
Compare train with
Most popular Train | Flight | Driving |
|---|---|---|
$171 Average price Cheapest | $537 Average price | $142 Average price (fuel + tolls) |
9h 1m Average total duration 8h 31m Onboard + 30m Additional time* | 4h 37m Average total duration Fastest 2h 37m Onboard + 2h 0m Additional time* | 7h 17m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 1.6 - 3.2kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Leverkusen to Prague:
A train is $366 less than a flight for this route with tickets for a flight from Leverkusen to Prague costing on average $537.
Other travel options to Prague take longer:
Train takes on average 9h 1m.
Tickets start at around $171 compared to roughly $142 in fuel and tolls — a saving of about $-28.67. The journey takes 8h 31m versus 7h 17m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Leverkusen to Prague
How to get from Leverkusen to Prague by train, bus or flight.
Our recommendation
The best way to travel from Leverkusen to Prague is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague)7:40 PM9h08Köln, Köln Bonn Flughafen (Terminal 2)4:48 AMPraha, ÚAN Florenc$491One-way0 transfers
Cheapest
(Amsterdam -> Prague)7:40 PM9h08Köln, Köln Bonn Flughafen (Terminal 2)4:48 AMPraha, ÚAN Florenc$491One-way0 transfers
Fastest
EW42412:45 PM1h10Cologne Bonn Airport3:55 PMPrague Vaclav Havel Airport$1011One-way0 transfers
Other options
28509 · ICE 621 · 3569+
3599:15 AM9h06Leverkusen Hbf6:21 PMPrague hlavní nádraží$1221One-way3 transfers
28513 · ICE 625 · 3573+
36111:15 AM9h06Leverkusen Hbf8:21 PMPrague hlavní nádraží$1431One-way3 transfers
28511 · ICE 557 · RJ 17710:15 AM9h00Leverkusen Hbf7:15 PMPrague-Holešovice$1851One-way2 transfers
(Amsterdam -> Prague)6:50 PM9h58Düsseldorf, ZOB am Hbf4:48 AMPraha, ÚAN Florenc$491One-way0 transfers
EW97747:05 PM1h15Dusseldorf Airport8:20 PMPrague Vaclav Havel Airport$821One-way0 transfers
EW97726:10 AM1h15Dusseldorf Airport7:25 AMPrague Vaclav Havel Airport$821One-way0 transfers
QS80457:05 PM1h15Dusseldorf Airport8:20 PMPrague Vaclav Havel Airport$1541One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Leverkusen to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Leverkusen to Prague.

This is compared to other travel options from Leverkusen to Prague:
A train is $366 less than a flight for this route with tickets for a flight from Leverkusen to Prague costing on average $537.
Other travel options to Prague take longer:
Train takes on average 9h 1m.
- Around 51 flights per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Leverkusen and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Leverkusen Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Leverkusen, Bf Mitte and arrive in Prague, Central Train Station.
- Flights mostly depart from Dusseldorf Airport and arrive in Prague Vaclav Havel Airport.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn to go to Prague by train.
- Travel with Lufthansa Cityline, KLM Cityhopper, Swiss, Eurowings, Lufthansa City Airlines, Air France, KLM, Air Dolomiti, Qatar Airways, Avion Express Malta, Austrian Airlines, Lufthansa, Smartwings, Air Baltic, Helvetic Airways, Lot Polish Airlines, British Airways to go to Prague by flight.
- 2 direct flights per day with Eurowings, Avion Express Malta, Smartwings.
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