Travel Information
Compare train and bus for Isernia to Naples
Omio recommends booking the train as it is the most popular option from Isernia to Naples among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €13 For those with little time, consider booking a bus, which has an average total journey time of 2h 28m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a bus costs an average of €13, while a train costs an average of €23.
Distance: 52 miles (85 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€23 Average price | €13 Average price Cheapest | €23 Average price (fuel + tolls) |
3h 21m Average total duration 2h 51m Onboard + 30m Additional time* | 2h 28m Average total duration Fastest 1h 58m Onboard + 30m Additional time* | 1h 43m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.2kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Isernia to Naples:
A bus is €10 less than a train for this route with tickets for a train from Isernia to Naples costing on average €23.
Other travel options to Naples take longer:
Train takes on average 3h 21m.
Tickets start at around €23 compared to roughly €23 in fuel and tolls — a saving of about €0.28. The journey takes 2h 51m versus 1h 43m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Isernia to Naples
How to get from Isernia to Naples by train, bus or flight.
Our recommendation
The best way to travel from Isernia to Naples is by taking a train because it’s the best combination of price and speed.
Regionale 51796:00 AM1h59Isernia station7:59 AMNaples Centrale€91One-way0 transfers
Cheapest
Regionale 51796:00 AM1h59Isernia station7:59 AMNaples Centrale€91One-way0 transfers
Fastest
FlixBus6:25 PM1h55Isernia, Piazza della Repubblica (F. Martino bus station)8:20 PMNaples, Metropark Centrale(Terminal Bus FS Park)€121One-way0 transfers
Other options
Regionale 51817:08 AM2h00Isernia station9:08 AMNaples Centrale€91One-way0 transfers
Regionale 51892:06 PM2h17Isernia station4:23 PMNaples Centrale€91One-way0 transfers
Regionale 51997:01 PM2h34Isernia station9:35 PMNaples Centrale€91One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Isernia to Naples
Travel to Naples easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Isernia to Naples.

This is compared to other travel options from Isernia to Naples:
A bus is €10 less than a train for this route with tickets for a train from Isernia to Naples costing on average €23.
Other travel options to Naples take longer:
Train takes on average 3h 21m.
- Around 7 trains per day.
- Around 1 buses per day.
However, we recommend checking specific travel dates for your route between Isernia and Naples as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Isernia station and arrive in Naples Centrale.
- Buses mostly depart from Isernia, Piazza della Repubblica (F. Martino bus station) and arrive in Naples, Metropark Centrale(Terminal Bus FS Park).
- Travel with FlixBus to go to Naples by bus.
- Travel with Frecciarossa, Intercity, Regionale, Intercity Notte to go to Naples by train.
- 1 direct buses per day with FlixBus.
- 4 direct trains per day with Regionale.
Travelling from Isernia to Naples: related information
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