Travel Information
Compare bus, train, and flight for Interlaken to Prague
Omio recommends booking the train as it is the most popular option from Interlaken to Prague among Omio's users. If you are prioritising price, take the train, with an average ticket price of €190 For those with little time, consider booking a flight, which has an average total journey time of 5h 0m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a train costs an average of €190, while a flight costs an average of €407.
Distance: 381 miles (614 km)
Compare train with
Most popular Train | Flight | Driving |
|---|---|---|
€190 Average price Cheapest | €407 Average price | €192 Average price (fuel + tolls) |
12h 22m Average total duration 11h 52m Onboard + 30m Additional time* | 5h 0m Average total duration Fastest 3h 0m Onboard + 2h 0m Additional time* | 8h 18m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions Lowest | 1.8 - 3.7kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Interlaken to Prague
Compare the available ways to get from Interlaken to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Interlaken to Prague:
A train is €218 less than a flight for this route with tickets for a flight from Interlaken to Prague costing on average €407.
Other travel options to Prague take longer:
Train takes on average 12h 22m.
Tickets start at around €190 compared to roughly €192 in fuel and tolls — a saving of about €3. The journey takes 11h 52m versus 8h 18m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Interlaken to Prague
How to get from Interlaken to Prague by train, bus or flight.
Our recommendation
The best way to travel from Interlaken to Prague is by taking a train because it’s the best combination of price and speed.
ICE 372 · ICE 565 · 88619 · 35738:04 AM 12h17 Interlaken West 8:21 PM Prague hlavní nádraží €79 1 One-way 4 transfers
Cheapest
ICE 372 · ICE 565 · 88619 · 35738:04 AM 12h17 Interlaken West 8:21 PM Prague hlavní nádraží €79 1 One-way 4 transfers
Fastest
LX14847:25 AM 1h20 Zurich Airport 8:45 AM Prague Vaclav Havel Airport €333 1 One-way 0 transfers
Other options
IC 628 · ICE 2 · ICE 590 · 165014:34 PM 16h36 Interlaken West 9:10 AM Prague hlavní nádraží €79 1 One-way 6 transfers
IC 10966 · ICE 370 · ICE 567 · 8862110:04 AM 12h18 Interlaken West 10:22 PM Prague hlavní nádraží €101 1 One-way 5 transfers
IC 10276 · ICE 276 · ICE 1657 · S12:04 PM 18h06 Interlaken West 8:10 AM Prague hlavní nádraží €121 1 One-way 5 transfers
U255479:50 AM 1h25 EuroAirport Basel Mulhouse Freiburg 11:15 AM Prague Vaclav Havel Airport €98 1 One-way 0 transfers
KL1926 · KL13517:10 PM 13h15 Zurich Airport 8:25 AM Prague Vaclav Havel Airport €151 1 One-way 1 transfer
KL1942 · KL13536:00 AM 4h50 EuroAirport Basel Mulhouse Freiburg 10:50 AM Prague Vaclav Havel Airport €154 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Interlaken to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Interlaken to Prague.

This is compared to other travel options from Interlaken to Prague:
A train is €218 less than a flight for this route with tickets for a flight from Interlaken to Prague costing on average €407.
Other travel options to Prague take longer:
Train takes on average 12h 22m.
- Around 84 flights per day.
- Around 9 trains per day.
However, we recommend checking specific travel dates for your route between Interlaken and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Zurich Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Interlaken West and arrive in Prague hlavní nádraží.
- Travel with KLM, British Airways, Air France, Lot Polish Airlines, Condor Flugdienst, Swiss, KLM Cityhopper, Austrian Airlines, Turkish Airlines, Lufthansa, Air Dolomiti, Air Baltic, Brussels Airlines, Qatar Airways, Eurowings, Helvetic Airways, Lufthansa Cityline, easyJet, Avion Express Malta, Croatia Airlines, TAP Portugal, Edelweiss Air, Egypt Air, Cityjet to go to Prague by flight.
- Travel with České dráhy, Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH to go to Prague by train.
- 5 direct flights per day with Swiss, Air Baltic, Helvetic Airways, easyJet, Edelweiss Air.
Travelling from Interlaken to Prague: related information
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