Travel Information
Compare bus, train, and flight for Heidelberg to Prague
Omio recommends booking the bus as it is the most popular option from Heidelberg to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $23. For those with little time consider booking a flight which can get you there in 1h 22m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $23, and a flight costs an average of $159.
Distance: 259 miles (418 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$39 Average price Cheapest | $74 Average price | $229 Average price | $109 Average price (fuel + tolls) |
7h 5m Average total duration 6h 35m Onboard + 30m Additional time* | 9h 0m Average total duration 8h 30m Onboard + 30m Additional time* | 4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* | 5h 36m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Heidelberg to Prague:
A bus is $35 (€29) less than a train for this route with tickets for a train from Heidelberg to Prague costing on average $74 (€61).
A bus is $190 (€156) less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average $229 (€188).
Other travel options to Prague take longer:
Bus takes on average 6h 35m.
Train takes on average 8h 30m.
Travel optionsfrom Heidelberg to Prague
How to get from Heidelberg to Prague by train, bus or flight.
Our recommendation
The best way to travel from Heidelberg to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus5:50 AM6h55Heidelberg, Hauptbahnhof12:45 PMPraha, Na Knížecí$521One-way0 transfers
Cheapest
FlixBus5:50 AM6h55Heidelberg, Hauptbahnhof12:45 PMPraha, Na Knížecí$521One-way0 transfers
Fastest
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel Airport$1761One-way0 transfers
Other options
S2 · ICE 772 · ICE 621 · 35699:33 AM8h48Heidelberg Hbf6:21 PMPrague hlavní nádraží$1351One-way4 transfers
ICE 117+
3599:13 AM9h08Heidelberg Hbf6:21 PMPrague hlavní nádraží$1591One-way1 transfer
19258 · ICE 376 · ICE 1557 · S18:10 AM9h00Heidelberg Hbf5:10 PMPrague hlavní nádraží$1841One-way5 transfers
FlixBus5:50 AM7h15Heidelberg, Hauptbahnhof1:05 PMPraha, ÚAN Florenc$521One-way0 transfers
FlixBus · FlixBus9:40 PM9h15Heidelberg, Hauptbahnhof6:55 AMPraha, ÚAN Florenc$611One-way1 transfer
FlixBus · FlixBus9:55 AM9h15Heidelberg, Hauptbahnhof7:10 PMPraha, Na Knížecí$761One-way1 transfer
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$1911One-way0 transfers
IC 2529 · ICE 25+
DE44118:24 AM13h01Heidelberg Hbf9:25 PMPrague Vaclav Havel Airport$2041One-way2 transfers
ICE 1094 · ICE 918+
DE441112:46 PM8h39Heidelberg Hbf9:25 PMPrague Vaclav Havel Airport$2131One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Heidelberg to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Heidelberg to Prague.

This is compared to other travel options from Heidelberg to Prague:
A bus is $35 (€29) less than a train for this route with tickets for a train from Heidelberg to Prague costing on average $74 (€61).
A bus is $190 (€156) less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average $229 (€188).
Other travel options to Prague take longer:
Bus takes on average 6h 35m.
Train takes on average 8h 30m.
- Around 59 flights per day.
- Around 10 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Heidelberg and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Buses mostly depart from Heidelberg, Hauptbahnhof and arrive in Praha, ÚAN Florenc.
- Trains mostly depart from Heidelberg Hbf and arrive in Prague hlavní nádraží.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Prague by bus.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy to go to Prague by train.
- Travel with Lufthansa, Condor Flugdienst, Swiss to go to Prague by flight.
- 5 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 8 direct flights per day with Lufthansa, Condor Flugdienst.
Travelling from Heidelberg to Prague: related information
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