Travel Information
Compare bus, train, and flight for Heidelberg to Prague
Omio recommends booking the bus as it is the most popular option from Heidelberg to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $49 For those with little time, consider booking a flight, which has an average total journey time of 4h 40m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $49, while a flight costs an average of $432.
Distance: 259 miles (418 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$49 Average price Cheapest | $142 Average price | $432 Average price | $108 Average price (fuel + tolls) |
7h 56m Average total duration 7h 26m Onboard + 30m Additional time* | 8h 31m Average total duration 8h 1m Onboard + 30m Additional time* | 4h 40m Average total duration Fastest 2h 40m Onboard + 2h 0m Additional time* | 5h 36m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Heidelberg to Prague:
A bus is $93 less than a train for this route with tickets for a train from Heidelberg to Prague costing on average $142.
A bus is $383 less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average $432.
Other travel options to Prague take longer:
Bus takes on average 7h 56m.
Train takes on average 8h 31m.
Tickets start at around $49 compared to roughly $108 in fuel and tolls — a saving of about $59. The journey takes 7h 26m versus 5h 36m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Heidelberg to Prague
How to get from Heidelberg to Prague by train, bus or flight.
Our recommendation
The best way to travel from Heidelberg to Prague is by taking a bus because it’s the best combination of price and speed.
305122:55 AM6h50Heidelberg, Alte Eppelheimer Straße (Hbf)9:45 AMPraha, ÚAN Florenc$321One-way0 transfers
Cheapest
305122:55 AM6h50Heidelberg, Alte Eppelheimer Straße (Hbf)9:45 AMPraha, ÚAN Florenc$321One-way0 transfers
Fastest
DE44118:35 PM1h00Frankfurt am Main Airport9:35 PMPrague Vaclav Havel Airport$1731One-way0 transfers
Other options
FlixBus4:15 PM6h40Heidelberg, Hauptbahnhof10:55 PMPraha, Na Knížecí$421One-way0 transfers
FlixBus4:15 PM6h55Heidelberg, Hauptbahnhof11:10 PMPraha, ÚAN Florenc$421One-way0 transfers
FlixBus5:50 AM6h55Heidelberg, Hauptbahnhof12:45 PMPraha, Na Knížecí$431One-way0 transfers
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$1871One-way0 transfers
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$2021One-way0 transfers
LO380 · LO5238:00 PM13h15Frankfurt am Main Airport9:15 AMPrague Vaclav Havel Airport$3161One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Heidelberg to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Heidelberg to Prague.

This is compared to other travel options from Heidelberg to Prague:
A bus is $93 less than a train for this route with tickets for a train from Heidelberg to Prague costing on average $142.
A bus is $383 less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average $432.
Other travel options to Prague take longer:
Bus takes on average 7h 56m.
Train takes on average 8h 31m.
- Around 63 flights per day.
- Around 14 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Heidelberg and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Heidelberg Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Heidelberg, Hauptbahnhof and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar Bus, KLR to go to Prague by bus.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy to go to Prague by train.
- Travel with Lufthansa, Condor Flugdienst, Swiss, Lufthansa Cityline, KLM Cityhopper, Brussels Airlines, Eurowings, KLM, Qatar Airways, Air Dolomiti, Austrian Airlines, braathens regional aviation, Air Baltic, Helvetic Airways, Lot Polish Airlines, TAP Portugal, British Airways, Edelweiss Air to go to Prague by flight.
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, KLR.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
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