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Compare train and bus for Brno to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Brno to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of CHF 52 For those with little time, consider booking a train, which has an average total journey time of 9h 40m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of CHF 52, while a train costs an average of CHF 158.
Distance: 359 miles (579 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
CHF 158 Average price | CHF 52 Average price Cheapest | CHF 123 Average price (fuel + tolls) |
9h 40m Average total duration Fastest 9h 10m Onboard + 30m Additional time* | 11h 40m Average total duration 11h 10m Onboard + 30m Additional time* | 6h 52m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.4kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Brno to Frankfurt am Main
Compare the available ways to get from Brno to Frankfurt am Main, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Brno to Frankfurt am Main:
A bus is CHF 106 less than a train for this route with tickets for a train from Brno to Frankfurt am Main costing on average CHF 158.
Other travel options to Frankfurt am Main take longer:
Bus takes on average 11h 40m.
Tickets start at around CHF 158 compared to roughly CHF 123 in fuel and tolls — a saving of about -CHF 34. The journey takes 9h 10m versus 6h 52m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Brno to Frankfurt am Main
How to get from Brno to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Brno to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.

5:10 PM 10h50 Brno 4:00 AM Frankfurt am Main CHF 38 1 One-way 0 transfers
Cheapest

5:10 PM 10h50 Brno 4:00 AM Frankfurt am Main CHF 38 1 One-way 0 transfers
Fastest

5:10 PM 10h50 Brno 4:00 AM Frankfurt am Main CHF 38 1 One-way 0 transfers
Other options

9:59 PM 14h31 Brno 12:30 PM Frankfurt am Main CHF 46 1 One-way 0 transfers
10:59 PM 15h01 Brno 2:00 PM Frankfurt am Main CHF 54 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Brno to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brno to Frankfurt am Main.

This is compared to other travel options from Brno to Frankfurt am Main:
A bus is CHF 106 less than a train for this route with tickets for a train from Brno to Frankfurt am Main costing on average CHF 158.
Other travel options to Frankfurt am Main take longer:
Bus takes on average 11h 40m.
- Around 13 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between Brno and Frankfurt am Main as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Vienna International Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Brno hlavní nádraží and arrive in Frankfurt (Main) Hbf.
- Buses mostly depart from Brno, Benešova - Grandhotel (Hlavní nádraží) and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Travel with FlixBus, Infobus to go to Frankfurt am Main by bus.
- Travel with České dráhy, Deutsche Bahn, Leo Express to go to Frankfurt am Main by train.
- 0 direct buses per day with Infobus.
Travelling from Brno to Frankfurt am Main: related information
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