Travel Information
Compare bus and train for Düsseldorf to Brno
Omio recommends booking the bus as it is the most popular option from Düsseldorf to Brno among Omio's users. If you are prioritising price, take the bus, with an average ticket price of zł 334 For those with little time, consider booking a train, which has an average total journey time of 11h 22m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.7kg. Average ticket prices depend on the travel mode: a bus costs an average of zł 334, while a train costs an average of zł 916.
Distance: 456 miles (734 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
zł 334 Average price Cheapest | zł 916 Average price | zł 716 Average price (fuel + tolls) |
15h 26m Average total duration 14h 56m Onboard + 30m Additional time* | 11h 22m Average total duration Fastest 10h 52m Onboard + 30m Additional time* | 9h 36m Average total duration (door-to-door) |
0.7 - 1.8kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Düsseldorf to Brno
Compare the available ways to get from Düsseldorf to Brno, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Düsseldorf to Brno:
A bus is zł 582 less than a train for this route with tickets for a train from Düsseldorf to Brno costing on average zł 916.
Other travel options to Brno take longer:
Bus takes on average 15h 26m.
Tickets start at around zł 334 compared to roughly zł 716 in fuel and tolls — a saving of about zł 382. The journey takes 14h 56m versus 9h 36m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Düsseldorf to Brno
How to get from Düsseldorf to Brno by train, bus or flight.
Our recommendation
The best way to travel from Düsseldorf to Brno is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague) · (Prague -> Vienna)6:50 PM 14h40 Düsseldorf, ZOB am Hbf 9:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží) zł 204 1 One-way 1 transfer
Cheapest
(Amsterdam -> Prague) · (Prague -> Vienna)6:50 PM 14h40 Düsseldorf, ZOB am Hbf 9:30 AM Brno, Benešova - Grandhotel (Hlavní nádraží) zł 204 1 One-way 1 transfer
Fastest
ICE 621 · 3569+
359+
RJ 2599:19 AM 11h54 Düsseldorf Hbf 9:13 PM Brno hlavní nádraží zł 231 1 One-way 3 transfers
Other options
ICE 103 · ICE 593 · EC 1217 · RJX 528:24 AM 12h17 Düsseldorf Hbf 8:41 PM Brno hlavní nádraží zł 212 1 One-way 3 transfers
ICE 849 · RJ 385 · RJ 57711:50 AM 12h51 Düsseldorf Hbf 12:41 AM Brno hlavní nádraží zł 212 1 One-way 2 transfers
ICE 105 · ICE 595 · ICE 211 · RJX 16710:24 AM 12h17 Düsseldorf Hbf 10:41 PM Brno hlavní nádraží zł 236 1 One-way 4 transfers
FlixBus · FlixBus7:30 AM 17h35 Düsseldorf, ZOB am Hbf 1:05 AM Brno, Benešova - Grandhotel (Hlavní nádraží) zł 217 1 One-way 1 transfer
FlixBus · FlixBus10:35 PM 15h05 Düsseldorf, ZOB am Hbf 1:40 PM Brno, Benešova - Grandhotel (Hlavní nádraží) zł 219 1 One-way 1 transfer
FlixBus · FlixBus1:30 AM 18h30 Düsseldorf, ZOB am Hbf 8:00 PM Brno, Benešova - Grandhotel (Hlavní nádraží) zł 219 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Düsseldorf to Brno
Travel to Brno easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Düsseldorf to Brno.

This is compared to other travel options from Düsseldorf to Brno:
A bus is zł 582 less than a train for this route with tickets for a train from Düsseldorf to Brno costing on average zł 916.
Other travel options to Brno take longer:
Bus takes on average 15h 26m.
- Around 9 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between Düsseldorf and Brno as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Düsseldorf Hbf and arrive in Brno hlavní nádraží.
- Buses mostly depart from Düsseldorf, ZOB am Hbf and arrive in Brno, Benešova - Grandhotel (Hlavní nádraží).
- Travel with FlixBus to go to Brno by bus.
- Travel with České dráhy, Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH to go to Brno by train.
Travelling from Düsseldorf to Brno: related information
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