Travel Information
Compare bus, train, and flight for Florence to Domodossola
Omio recommends booking the train as it is the most popular option from Florence to Domodossola among Omio's users. If you are prioritising price, take the train, with an average ticket price of $28 For those with little time, consider booking a train, which has an average total journey time of 4h 33m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a train costs an average of $28, while a flight costs an average of $411.
Distance: 217 miles (350 km)
Compare train with
Most popular Train | Flight | Driving |
|---|---|---|
$28 Average price Cheapest | $411 Average price | $124 Average price (fuel + tolls) |
4h 33m Average total duration Fastest 4h 3m Onboard + 30m Additional time* | 4h 59m Average total duration 2h 59m Onboard + 2h 0m Additional time* | 4h 31m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Florence to Domodossola
Compare the available ways to get from Florence to Domodossola, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Florence to Domodossola:
A train is $384 less than a flight for this route with tickets for a flight from Florence to Domodossola costing on average $411.
Other travel options to Domodossola take longer:
Flight takes on average 4h 59m.
The journey is about 28m faster (4h 3m by train vs 4h 31m by car) and roughly $97 cheaper once you factor in fuel and tolls ($28 vs $124). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Florence to Domodossola
How to get from Florence to Domodossola by train, bus or flight.
Our recommendation
The best way to travel from Florence to Domodossola is by taking a train because it’s the best combination of price and speed.
Intercity 590+
Regionale TRENORD 24403:33 PM 6h32 Florence Rifredi 10:05 PM Domodossola station $29 1 One-way 1 transfer
Cheapest
Intercity 590+
Regionale TRENORD 24403:33 PM 6h32 Florence Rifredi 10:05 PM Domodossola station $29 1 One-way 1 transfer
Fastest
AZ1682 · AZ20503:30 PM 3h40 Florence Peretola Airport 7:10 PM Milan Linate Airport $340 1 One-way 1 transfer
Other options
Intercity 580+
Regionale TRENORD 2424 · Autobus TRENORD 2426A8:21 AM 7h29 Florence Santa Maria Novella 3:50 PM Domodossola station $33 1 One-way 2 transfers
Intercity 580+
Regionale TRENORD 24288:21 AM 7h44 Florence Santa Maria Novella 4:05 PM Domodossola station $33 1 One-way 1 transfer
FRECCIAROSSA 9310+
Regionale TRENORD 242812:10 PM 3h55 Florence Santa Maria Novella 4:05 PM Domodossola station $39 1 One-way 1 transfer
AZ1678 · AZ208011:25 AM 4h45 Florence Peretola Airport 4:10 PM Milan Linate Airport $184 1 One-way 1 transfer
AZ1678 · AZ204411:25 AM 3h45 Florence Peretola Airport 3:10 PM Milan Linate Airport $185 1 One-way 1 transfer
AZ1678 · AZ203811:25 AM 4h15 Florence Peretola Airport 3:40 PM Milan Linate Airport $185 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Florence to Domodossola
Travel to Domodossola easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Domodossola.

This is compared to other travel options from Florence to Domodossola:
A train is $384 less than a flight for this route with tickets for a flight from Florence to Domodossola costing on average $411.
Other travel options to Domodossola take longer:
Flight takes on average 4h 59m.
- Around 33 trains per day.
- Around 13 flights per day.
However, we recommend checking specific travel dates for your route between Florence and Domodossola as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Milan Linate Airport.
- Trains mostly depart from Florence Santa Maria Novella and arrive in Domodossola station.
- Travel with Italo, Frecciarossa, Regionale, Intercity, Intercity Notte to go to Domodossola by train.
- Travel with ITA, British Airways, BA Cityflyer to go to Domodossola by flight.
Travelling from Florence to Domodossola: related information
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