Travel Information
Compare bus and train for Florence to Domodossola
Omio recommends booking the train as it is the most popular option from Florence to Domodossola among Omio's users. If you are prioritising price take the train with prices starting from $29. For those with little time consider booking a bus which can get you there in 4h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of $29, and a bus costs an average of $88.
Distance: 217 miles (350 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$45 Average price Cheapest | $92 Average price | $125 Average price (fuel + tolls) |
5h 15m Average total duration 4h 45m Onboard + 30m Additional time* | 4h 55m Average total duration Fastest 4h 25m Onboard + 30m Additional time* | 4h 31m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.9kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Florence to Domodossola:
A train is $46 (€38) less than a bus for this route with tickets for a bus from Florence to Domodossola costing on average $92 (€75).
Other travel options to Domodossola take longer:
Train takes on average 4h 45m.
Travel optionsfrom Florence to Domodossola
How to get from Florence to Domodossola by train, bus or flight.
Our recommendation
The best way to travel from Florence to Domodossola is by taking a bus because it’s the best combination of price and speed.
8:55 AM4h25Florence1:20 PMDomodossola$891One-way0 transfers
Cheapest
8:55 AM4h25Florence1:20 PMDomodossola$891One-way0 transfers
Fastest
8:55 AM4h25Florence1:20 PMDomodossola$891One-way0 transfers
Other options
7:55 AM4h25Florence12:20 PMDomodossola$951One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Florence to Domodossola
Travel to Domodossola easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Domodossola.

This is compared to other travel options from Florence to Domodossola:
A train is $46 (€38) less than a bus for this route with tickets for a bus from Florence to Domodossola costing on average $92 (€75).
Other travel options to Domodossola take longer:
Train takes on average 4h 45m.
- Around 16 flights per day.
- Around 12 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Florence and Domodossola as scheduled services by bus and train can vary by season or day of the week.
- Flights mostly depart from Florence Peretola Airport and arrive in Milan Malpensa Airport.
- Trains mostly depart from Florence Santa Maria Novella and arrive in Domodossola station.
- Travel with FlixBus to go to Domodossola by bus.
- Travel with Italo, Frecciarossa, Regionale, Intercity, Trenitalia, Intercity Notte to go to Domodossola by train.
Travelling from Florence to Domodossola: related information
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