Travel Information
Compare bus and train for Mendrisio to Domodossola
Omio recommends booking the bus as it is the most popular option from Mendrisio to Domodossola among Omio's users. If you are prioritising price take the bus with prices starting from $17. For those with little time consider booking a train which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of $17, and a train costs an average of $92.
Distance: 37 miles (60 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$17 Average price Cheapest | $92 Average price |
13h 50m Average total duration 13h 20m Onboard + 30m Additional time* | 3h 29m Average total duration Fastest 2h 59m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Travel optionsfrom Mendrisio to Domodossola
How to get from Mendrisio to Domodossola by train, bus or flight.
Our recommendation
The best way to travel from Mendrisio to Domodossola is by taking a bus because it’s the best combination of price and speed.

Cheapest

Fastest

Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Mendrisio to Domodossola
Travel to Domodossola easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mendrisio to Domodossola.

This is compared to other travel options from Mendrisio to Domodossola:
A bus is $75 (€61) less than a train for this route with tickets for a train from Mendrisio to Domodossola costing on average $92 (€75).
Other travel options to Domodossola take longer:
Bus takes on average 13h 20m.
- Around 4 trains per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Mendrisio and Domodossola as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Mendrisio station and arrive in Domodossola station.
- Travel with FlixBus to go to Domodossola by bus.
- Travel with Trenord to go to Domodossola by train.
Travelling from Mendrisio to Domodossola: related information
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