Travel Information
Compare train and bus for Comiso to Messina
Omio recommends booking the train as it is the most popular option from Comiso to Messina among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €22 For those with little time, consider booking a bus, which has an average total journey time of 5h 29m. Average ticket prices depend on the travel mode: a bus costs an average of €22, while a train costs an average of €23.
Distance: 100 miles (161 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€23 Average price | €22 Average price Cheapest | €33 Average price (fuel + tolls) |
6h 12m Average total duration 5h 42m Onboard + 30m Additional time* | 5h 29m Average total duration Fastest 4h 59m Onboard + 30m Additional time* | 2h 37m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Compare ways to travel from Comiso to Messina
Compare the available ways to get from Comiso to Messina, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Comiso to Messina:
A bus is €1 less than a train for this route with tickets for a train from Comiso to Messina costing on average €23.
Other travel options to Messina take longer:
Train takes on average 6h 12m.
Tickets start at around €23 compared to roughly €33 in fuel and tolls — a saving of about €10. The journey takes 5h 42m versus 2h 37m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Comiso to Messina
How to get from Comiso to Messina by train, bus or flight.
Our recommendation
The best way to travel from Comiso to Messina is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus2:45 PM 5h25 Comiso, Via Ghandi (Fermata Sais Comiso) 8:10 PM Messina, Piazza Della Repubblica (Stazione Centrale) €19 1 One-way 1 transfer
Cheapest
FlixBus · FlixBus2:45 PM 5h25 Comiso, Via Ghandi (Fermata Sais Comiso) 8:10 PM Messina, Piazza Della Repubblica (Stazione Centrale) €19 1 One-way 1 transfer
Fastest
FlixBus · FlixBus2:45 PM 5h25 Comiso, Via Ghandi (Fermata Sais Comiso) 8:10 PM Messina, Piazza Della Repubblica (Stazione Centrale) €19 1 One-way 1 transfer
Other options
Regionale Veloce 5466 · Regionale Veloce 5506 · Regionale 129746:33 AM 6h23 Comiso station 12:56 PM Messina Centrale €23 1 One-way 2 transfers
Regionale Veloce 5466 · Regionale Veloce 5506 · Regionale 129746:33 AM 6h23 Comiso station 12:56 PM Messina Centrale €23 1 One-way 2 transfers
Regionale Veloce 5468 · Regionale Veloce 5508 · Regionale 129788:30 AM 6h36 Comiso station 3:06 PM Messina Centrale €23 1 One-way 2 transfers
FlixBus · FlixBus2:45 PM 6h40 Comiso, Via Ghandi (Fermata Sais Comiso) 9:25 PM Messina, Piazza Della Repubblica (Stazione Centrale) €19 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Comiso to Messina
Travel to Messina easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Comiso to Messina.

This is compared to other travel options from Comiso to Messina:
A bus is €1 less than a train for this route with tickets for a train from Comiso to Messina costing on average €23.
Other travel options to Messina take longer:
Train takes on average 6h 12m.
- Around 9 trains per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Comiso and Messina as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Comiso station and arrive in Messina Centrale.
- Buses mostly depart from Comiso, Via Ghandi (Fermata Sais Comiso) and arrive in Messina, Piazza Della Repubblica (Stazione Centrale).
- Travel with Regionale, Intercity to go to Messina by train.
- Travel with FlixBus to go to Messina by bus.
Travelling from Comiso to Messina: related information
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