The cheapest and fastest trains from St. Louis, MO to Roanoke, VA
Cheapest price
$380
Average price
$380
Fastest journey
1 d 12 h 56 m
Average duration
1 d 12 h 56 m
Trains per day
1
Distance
911 km
The best way to find a cheap train ticket from St. Louis, MO to Roanoke, VA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Roanoke, VA will cost around $380 if you buy it on the day, but the cheapest tickets can be found for only $380.
Of the 1 trains that leave St. Louis, MO for Roanoke, VA on Wed, May 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, May 20 the direct trains cover the 911 km distance in an average of 1 d 12 h 56 m but if you time it right, some trains will get you there in just 1 d 12 h 56 m .
On Wed, May 20 the slowest trains will take 1 d 12 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:10 PM36h56St. Louis, MO2:06 AMRoanoke, VA$3801One-way0 transfers
1:10 PM36h56St. Louis, MO2:06 AMRoanoke, VA$3801One-way0 transfers
Travel Information
Compare train, bus, and flight for St. Louis, MO to Roanoke, VA
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Roanoke, VA among Omio's users. If you are prioritising price take the bus with prices starting from $106. For those with little time consider booking a flight which can get you there in 5h 10m. The ticket price range depends on the travel mode: a bus costs an average of $106, and a flight costs an average of $384.
Distance: 566 miles (911 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$427 Average price | $198 Average price Cheapest | $496 Average price | $138 Average price (fuel + tolls) |
28h 49m Average total duration 28h 19m Onboard + 30m Additional time* | 19h 32m Average total duration 19h 2m Onboard + 30m Additional time* | 8h 10m Average total duration Fastest 5h 10m Onboard + 3h 0m Additional time* | 10h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from St. Louis, MO to Roanoke, VA:
A bus is $229 (€184) less than a train for this route with tickets for a train from St. Louis, MO to Roanoke, VA costing on average $427 (€344).
A bus is $298 (€240) less than a flight for this route with tickets for a flight from St. Louis, MO to Roanoke, VA costing on average $496 (€400).
Other travel options to Roanoke, VA take longer:
Bus takes on average 19h 2m.
Train takes on average 28h 19m.
Tickets start at around $427 (€344) compared to roughly $138 (€111) in fuel and tolls — a saving of about $-288.67 (€-232.80). The journey takes 28h 19m versus 10h 15m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
St. Louis, MO to Roanoke, VA train times
The table below shows live departures for St. Louis, MO to Roanoke, VA trains for today, Tuesday, May 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:10 PM St. Louis, MO | 36h56 | 2:06 AM Roanoke, VA | 0 transfersDirect | |
![]() | 2:10 PM St. Louis, MO | 37h03 | 3:13 AM Roanoke, VA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Roanoke, VA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 20
May 21
May 22
May 23
May 24
May 25
May 26
Journey information
Overview: Train from St. Louis, MO to Roanoke, VA
Trains from St. Louis, MO to Roanoke, VA run on average 1 times per day, taking around 28h 19m. Cheap train tickets for this journey start at $181 (€146) but you can travel from only $106 (€85) by bus.
The earliest train runs at 06:15, the last at 08:56. The fastest train covers the 566 miles (911 km) distance in 36h 56m.
Distance 566 miles (911 km) |
Average train duration 28h 19m |
Cheapest ticket price $181 (€146) |
Trains per day 1 |
Fastest train 36h 56m |
First train 6:15 AM |
Last train 8:56 AM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Train companies: Amtrak from St. Louis, MO to Roanoke, VA trainsAmtrak trains will get you between St. Louis, MO and Roanoke, VA from $106 (€85). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Louis, MO to Roanoke, VA
Find answers to the most common questions about traveling from St. Louis, MO to Roanoke, VA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Louis, MO to Roanoke, VA
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
- 6:00 AM - 10:00 PM Monday - Sunday
- Outside the station.
- Ramps.
- Hotel Roanoke & Conference Center
- Hampton Inn & Suites Roanoke-Downtown
- Cambria Hotel Downtown Roanoke
- Located near the platform
- The station consists of a single platform serving Amtrak's Northeast Regional line.
- Bus: Thruway bus connections available between Roanoke and Virginia Tech and Blacksburg
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to Roanoke, VA
Here are some other resources that might have the information you need
