- Must visit
Taubman Museum of Art
Major downtown art museum known for its striking contemporary architecture and rotating American art exhibitions.
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Travel Information
Compare train, bus, and flight for St. Louis, MO to Roanoke, VA
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Roanoke, VA among Omio's users. If you are prioritising price take the bus with prices starting from $104. For those with little time consider booking a flight which can get you there in 5h 10m. The ticket price range depends on the travel mode: a bus costs an average of $104, and a flight costs an average of $377.
Distance: 566 miles (911 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$419 Average price | $194 Average price Cheapest | $487 Average price | $136 Average price (fuel + tolls) |
28h 49m Average total duration 28h 19m Onboard + 30m Additional time* | 19h 32m Average total duration 19h 2m Onboard + 30m Additional time* | 8h 10m Average total duration Fastest 5h 10m Onboard + 3h 0m Additional time* | 10h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Roanoke, VA is a bus with an average price of $194 (€160).
This is compared to other travel options from St. Louis, MO to Roanoke, VA:
A bus is $225 (€184) less than a train for this route with tickets for a train from St. Louis, MO to Roanoke, VA costing on average $419 (€344).
A bus is $293 (€240) less than a flight for this route with tickets for a flight from St. Louis, MO to Roanoke, VA costing on average $487 (€400).
The fastest way to travel from St. Louis, MO to Roanoke, VA is by flight with an average journey time of 5h 10m.
Other travel options to Roanoke, VA take longer:
Bus takes on average 19h 2m.
Train takes on average 28h 19m.
It's helpful to compare your options as there are 3 ways to travel between St. Louis, MO and Roanoke, VA including taking a train, bus, and flight.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Roanoke, VA among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $419 (€344) compared to roughly $136 (€111) in fuel and tolls — a saving of about $-283.56 (€-232.80). The journey takes 28h 19m versus 10h 15m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
St. Louis, MO to Roanoke, VA train times
The table below shows live departures for St. Louis, MO to Roanoke, VA trains for today, Friday, July 3. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 22 Texas Eagle · 41 Floridian · 147 Northeast Regional | 8:10 AM St. Louis Station, St. Louis, MO | 36h56 | 10:06 PM Roanoke Station, Roanoke, VA | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Roanoke, VA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from St. Louis, MO to Roanoke, VA
USAUSA
Trains from St. Louis, MO to Roanoke, VA run on average 1 times per day, taking around 28h 19m. Cheap train tickets for this journey start at $178 (€146) but you can travel from only $104 (€85) by bus.
The earliest train runs at 06:15, the last at 08:56. The fastest train covers the 566 miles (911 km) distance in 36h 56m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $104 (€85)
Distance 566 miles (911 km) |
Average train duration 28h 19m |
Cheapest ticket price $178 (€146) |
Trains per day 1 |
Fastest train 36h 56m |
First train 6:15 AM |
Last train 8:56 AM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $104 (€85)
Train companies: Amtrak from St. Louis, MO to Roanoke, VA trainsAmtrak trains will get you between St. Louis, MO and Roanoke, VA from $104 (€85). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
36h 56m
Cheapest Price
$178 (€146)
Amtrak frequency
1 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Roanoke
Things to do in Roanoke
Discover the best of Roanoke — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Roanoke trip today.
- Must visit
Virginia Museum of Transportation
Well-regarded museum featuring locomotives, rail history, automobiles, and aviation exhibits tied to Roanoke's railroad heritage.
- Recommended
O. Winston Link Museum
Specialized photography museum dedicated to O. Winston Link's iconic images and recordings of Norfolk & Western steam railroading.
- Must visit
Mill Mountain Park
Large mountaintop park with overlooks, trails, and access to the Roanoke Star, offering the city's classic panoramic views.
- Must visit
Downtown Roanoke
Walkable core with markets, museums, murals, nightlife, and rail heritage, making it the main area for first-time visitors.
- Must visit
Blue Ridge Parkway Overlooks near Roanoke
Scenic mountain viewpoints just outside the city, especially popular for drives, foliage, sunrise photos, and social media content.
Virginia Ham Biscuits
Small biscuits filled with salty cured Virginia ham, a classic snack across Virginia and common at gatherings and brunches.
- Vegetarian
- Gluten-free
Pimento Cheese
A Southern spread made with cheese, pimentos, and mayonnaise, often served with crackers or in sandwiches and popular in Virginia.
- Vegetarian
- Gluten-free
Fried Apples
A traditional Appalachian side dish of skillet-cooked apples with butter and spices, reflecting the mountain food culture around Roanoke.
The River And Rail
A well-known neighborhood restaurant focused on seasonal Southern cooking, craft cocktails, and an upscale but relaxed atmosphere.
Texas Tavern
An iconic Roanoke institution known for chili dogs, burgers, and late-night counter service in a tiny historic setting.
Billy's
A long-established downtown restaurant and bar known for steaks, seafood, and an elegant historic dining room suitable for a finer meal.
United States Dollar
Roanoke is generally affordable by U.S. city standards, with reasonable dining and coffee prices and lodging that is usually mid-range rather than high-cost.
Average meal costs
- Budget
- USD 10-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 50-90 per person before drinks and tip.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at sit-down restaurants; 15-20% for delivery; USD 1-2 per drink at bars; round up or tip 10% for taxis; tip hotel staff and salon services.
FAQs: Trains from St. Louis, MO to Roanoke, VA
Find answers to the most common questions about traveling from St. Louis, MO to Roanoke, VA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Roanoke, VA, this guide helps you travel smarter and with confidence.
Train ticket prices from St. Louis, MO to Roanoke, VA can vary. The cheapest ticket starts at $178 (€146), while the average price is around $419 (€344).
The train from St. Louis, MO to Roanoke, VA runs once a day and takes approximately 36h 56m.
The distance by train from St. Louis, MO to Roanoke, VA is 566 miles (911 km).
The first train from St. Louis, MO to Roanoke, VA leaves at 6:15 AM.
The last train from St. Louis, MO to Roanoke, VA leaves at 8:56 AM.
There is no high speed train available from St. Louis, MO to Roanoke, VA.
There is no direct train service currently available from St. Louis, MO to Roanoke, VA.
Unfortunately, there is no night train available from St. Louis, MO to Roanoke, VA.
The train station in St. Louis, MO that goes to Roanoke, VA is St. Louis Station, St. Louis, MO, which connects to Roanoke Station, Roanoke, VA.
The cheapest way to get from St. Louis, MO to Roanoke, VA is by bus, with a cost of around $104 (€85).
The train journey from St. Louis, MO to Roanoke, VA offers scenic views, including rolling hills, lush forests, and picturesque landscapes, particularly as the route passes through the Appalachian region.
A day trip from St. Louis, MO to Roanoke, VA is not feasible since the travel time is 36h 56m with a frequency of 2 trips per day for trains, covering a distance of 566 miles (911 km).
Three to four days in Roanoke, VA, is recommended to explore its outdoor attractions, cultural sites, and local dining experiences effectively.
Yes, you can take the train from St. Louis, MO to Roanoke, VA.
Since neither St. Louis, MO nor Roanoke, VA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from Roanoke, VA include Lynchburg, VA.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Roanoke, VA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Roanoke, VA, travelers should be cautious of petty theft and pickpocketing, especially in crowded areas and popular tourist spots. It is advisable to stay alert when using rideshare services or taxis, ensuring the vehicle and driver match the app details. Travelers should also be aware of occasional scams involving unsolicited offers for tours or accommodations and avoid sharing personal or payment information with unverified sources. Staying in well-lit and populated areas at night enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from St. Louis, MO to Roanoke, VA
Most St. Louis, MO to Roanoke, VA trains use the St. Louis Station to Roanoke Station station pair. Use this guide to compare St. Louis, MO and Roanoke, VA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in St. Louis
Arrival train stations in Roanoke
Which St. Louis, MO station do trains to Roanoke, VA leave from?
Trains from St. Louis, MO to Roanoke, VA leave from St. Louis Station. The station is 0 miles (1 km) from St. Louis, MO city centre at 430 S 15th St, St. Louis, MO 63103, USA.
St. Louis Station430 S 15th St, St. Louis, MO 63103, USA+1 800-872-7245
City-centre transport
Getting to St. Louis Station from St. Louis city centre
TrainMlb, Mlr · 3m · $4 · every ~14 min
St. Louis Station train station facilities and services
St. Louis Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Landry's Seafood House, The Station Grille
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at St. Louis Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at St. Louis Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at St. Louis Station: Parking, Taxis, WC.
Bike and car services
Available at St. Louis Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at St. Louis Station: Ramps, restrooms.
Shops, hotels and contact
Nearby hotels include St. Louis Union Station Hotel, Curio Collection by Hilton, Courtyard St. Louis Downtown West, Drury Inn St. Louis at Union Station.
Which Roanoke, VA station do trains from St. Louis, MO arrive at?
Trains from St. Louis, MO to Roanoke, VA arrive at Roanoke Station. Roanoke Station is from Roanoke, VA city centre.
Roanoke Station55 Norfolk Avenue SW, Roanoke, VA 24011, USA
City-centre transport
Getting to Roanoke Station from Roanoke city centre
BusThruway bus connections available between Roanoke and Virginia Tech and Blacksburg
Roanoke Station train station facilities and services
Roanoke Station has practical services for this route, including Dining, Taxis, Accessibility, Hotel, Ticket Office, Bike Rental, and Information Desk.
Food and drink
Food and drink options are available at Roanoke Station.
Tickets and information
Ticket office support is available at Roanoke Station. Information desks are located near the platform.
Parking, taxis and toilets
Available at Roanoke Station: Taxis.
Bike and car services
Available at Roanoke Station: Bike Rental.
Accessibility
Accessibility facilities are available at Roanoke Station: Ramps.
Shops, hotels and contact
Nearby hotels include Hotel Roanoke & Conference Center, Hampton Inn & Suites Roanoke-Downtown, Cambria Hotel Downtown Roanoke.
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to Roanoke, VA
Here are some other resources that might have the information you need
Most popular trains to and from Roanoke, VA and St. Louis, MO
Most popular train connections to Roanoke, VA
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