The cheapest and fastest trains from Pisa Centrale to Brindisi
Cheapest price
$96
Average price
$96
Fastest journey
11 h 55 m
Average duration
11 h 55 m
Trains per day
1
Distance
709 km
The best way to find a cheap train ticket from Pisa Centrale to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Brindisi will cost around $96 if you buy it on the day, but the cheapest tickets can be found for only $96.
Of the 1 trains that leave Pisa Centrale for Brindisi on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct trains cover the 709 km distance in an average of 11 h 55 m but if you time it right, some trains will get you there in just 11 h 55 m .
On Fri, Nov 07 the slowest trains will take 11 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for Pisa Centrale to Brindisi
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €43. For those with little time consider booking a flight which can get you there in 1h 25m. The ticket price range depends on the travel mode: a bus costs an average of €43, and a train costs an average of €47.
Distance: 440 miles (709 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€61 Average price | €60 Average price | €58 Average price Cheapest |
12h 11m Average total duration 11h 41m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 14h 40m Average total duration 14h 10m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Pisa Centrale to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Train from Pisa Centrale to Brindisi
Trains from Pisa Centrale to Brindisi run on average 15 times per day, taking around 11h 41m. Cheap train tickets for this journey start at $57 (€47) but you can travel from only $36 (€29) by flight.
The earliest train runs at 00:21, the last at 19:10. The fastest train covers the 440 miles (709 km) distance in 11h 55m.
Distance 440 miles (709 km) |
Average train duration 11h 41m |
Cheapest ticket price $57 (€47) |
Trains per day 15 |
Fastest train 11h 55m |
First train 00:21 |
Last train 19:10 |
Train companies: Intercity Notte, Regionale from Pisa Centrale to Brindisi trainsIntercity Notte, Regionale trains will get you between Pisa Centrale and Brindisi from $36 (€29). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Regionale
FAQs: Trains from Pisa Centrale to Brindisi
Find answers to the most common questions about traveling from Pisa Centrale to Brindisi by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Pisa Centrale to Brindisi
- Mon - Sun: 06:00 - 20:30
- There is free Wi-Fi available at the McDonald's.
- There is a luggage storage office near the end of Platform 1.
- McDonald's
- Panetteria Binario 1
- Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
- Hotel NH Pisa
- Hotel La Pace
- Hotel Maria
- Mon - Sun: 06:00 - 20:30
- Located just outside the station on Piazza Vittorio Emanuele II.
- Bus lines: 1
- Train lines: Pisamover (S2), FA, FB, IC, ICN, RV, R, EN
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 1:00 a.m. Access is available via Piazza Crispi.
- Ristorante La Locanda del Porto
- McDonald's Brindisi
- Outside the main entrance.
- €1
- Palazzo Virgilio Hotel
- Hotel Orientale
- Grande Albergo Internazionale
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to regional and long-distance destinations
- Bus: Several lines available
- Taxi services available
Most popular train connections from Pisa Centrale
More options for your journey from Pisa Centrale to Brindisi
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