4.9
4.6The cheapest and fastest trains from Florence Santa Maria Novella to Palermo Centrale
Cheapest price on Sep 12
$136
Average ticket price on Sep 12
$172
Fastest journey on Sep 12
12 h 44 m
Average journey duration on Sep 12
14 h 25 m
Trains on Sep 12
6
Distance
655 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Palermo Centrale will cost around $172 if you buy it on the day, but the cheapest tickets can be found for only $136.
It's difficult to get from Florence Santa Maria Novella to Palermo Centrale without transferring at least once.
Regionale 18781+
Intercity 594+
InterCityNotte 19596:22 PM17h33Florence Santa Maria Novella11:55 AMPalermo Centrale$1361One-way2 transfers- Intercity 581 · Intercity 551 · Intercity 7275:45 AM17h13Florence Santa Maria Novella10:58 PMPalermo Centrale$1631One-way2 transfers
FRECCIAROSSA 9503+Intercity 7236:00 AM13h04Florence Santa Maria Novella7:04 PMPalermo Centrale$1721One-way1 transfer- FRECCIAROSSA 9519+Intercity 72710:14 AM12h44Florence Santa Maria Novella10:58 PMPalermo Centrale$1721One-way1 transfer
- FRECCIAROSSA 9435+InterCityNotte 19598:48 PM15h07Florence Santa Maria Novella11:55 AMPalermo Centrale$1881One-way1 transfer
- FRECCIAROSSA 9519+Intercity 72710:14 AM12h44Florence Santa Maria Novella10:58 PMPalermo Centrale$1721One-way1 transfer
- FRECCIAROSSA 9503+Intercity 7236:00 AM13h04Florence Santa Maria Novella7:04 PMPalermo Centrale$1721One-way1 transfer
- FRECCIAROSSA 9555+InterCityNotte 19557:14 PM13h59Florence Santa Maria Novella9:13 AMPalermo Centrale$1991One-way1 transfer
- FRECCIAROSSA 9435+InterCityNotte 19598:48 PM15h07Florence Santa Maria Novella11:55 AMPalermo Centrale$1881One-way1 transfer
- Intercity 581 · Intercity 551 · Intercity 7275:45 AM17h13Florence Santa Maria Novella10:58 PMPalermo Centrale$1631One-way2 transfers
Travel Information
Compare train, bus, flight, and ferry for Florence Santa Maria Novella to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Palermo Centrale among Omio's users. If you are prioritising price, take the ferry, with an average ticket price of $61 For those with little time, consider booking a flight, which has an average total journey time of 4h 42m. Average ticket prices depend on the travel mode: a ferry costs an average of $61, while a flight costs an average of $411.
Distance: 406 miles (655 km)
Compare train with
Most popular Train | Bus | Flight | Ferry | Driving |
|---|---|---|---|---|
$176 Average price | $152 Average price | $411 Average price | $61 Average price Cheapest | $78 Average price (fuel + tolls) |
14h 58m Average total duration 14h 28m Onboard + 30m Additional time* | 23h 17m Average total duration 22h 47m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 2h 42m Onboard + 2h 0m Additional time* | 20h 35m Average total duration 19h 35m Onboard + 1h 0m Additional time* | 24h 14m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company |  Most popular airline |  Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence Santa Maria Novella to Palermo Centrale:
A ferry is $91 (€73) less than a bus for this route with tickets for a bus from Florence Santa Maria Novella to Palermo Centrale costing on average $152 (€123).
A ferry is $114 (€93) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Palermo Centrale costing on average $176 (€142).
A ferry is $350 (€283) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Palermo Centrale costing on average $411 (€332).
Other travel options to Palermo Centrale take longer:
Train takes on average 14h 28m.
Ferry takes on average 19h 35m.
Bus takes on average 22h 47m.
You'll arrive about 9h 46m sooner (14h 28m by train vs 24h 14m by car). Tickets start at around $176 (€142) compared to roughly $78 (€63) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Live departures
Florence Santa Maria Novella to Palermo Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Palermo Centrale trains for today, Friday, September 11. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| Regionale Veloce 4085+Intercity 594+InterCityNotte 1959 | 6:14 PM Florence Santa Maria Novella | 18h36 | 12:50 PM Palermo Centrale | 2 transfers | |
| FRECCIAROSSA 9325+InterCityNotte 1955 | 6:59 PM Florence Santa Maria Novella | 14h14 | 9:13 AM Palermo Centrale | 1 transfer | |
| FRECCIAROSSA 9437+InterCityNotte 1959 | 9:48 PM Florence Santa Maria Novella | 15h02 | 12:50 PM Palermo Centrale | 1 transfer | |
| Saturday, September 12 | |||||
| Intercity 581 · Intercity 551 · Intercity 727 | 5:45 AM Florence Santa Maria Novella | 17h13 | 10:58 PM Palermo Centrale | 2 transfers | |
| FRECCIAROSSA 9503+Intercity 723 | 6:00 AM Florence Santa Maria Novella | 13h04 | 7:04 PM Palermo Centrale | 1 transfer | |
| FRECCIAROSSA 9519+Intercity 727 | 10:14 AM Florence Santa Maria Novella | 12h44 | 10:58 PM Palermo Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Palermo Centrale by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence Santa Maria Novella to Palermo Centrale trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Florence Santa Maria Novella to Palermo Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Florence Santa Maria Novella to Palermo Centrale.
Journey information
Overview: Train from Florence Santa Maria Novella to Palermo Centrale
ItalyItaly
Trains from Florence Santa Maria Novella to Palermo Centrale run on average 5 times per day, taking around 14h 28m. Cheap train tickets for this journey start at $93 (€75) but you can travel from only $29 (€23) by flight.
The earliest train runs at 01:13, the last at 22:40. The fastest train covers the 406 miles (655 km) distance in 11h 22m.
Distance 406 miles (655 km) |
Average train duration 14h 28m |
Cheapest ticket price $93 (€75) |
Trains per day 5 |
Fastest train 11h 22m |
First train 1:13 AM |
Last train 10:40 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 1 day |
Train companies: Intercity, Intercity Notte from Florence Santa Maria Novella to Palermo Centrale trainsIntercity, Intercity Notte trains will get you between Florence Santa Maria Novella and Palermo Centrale from $29 (€23). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity
Intercity Notte
FAQs: Trains from Florence Santa Maria Novella to Palermo Centrale
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.
popular train stations
Popular train stations from Florence Santa Maria Novella to Palermo Centrale
Most Florence Santa Maria Novella to Palermo Centrale trains use the Firenze Santa Maria Novella to Enna station pair. Use this guide to compare Florence Santa Maria Novella and Palermo Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Palermo Centrale
Here are some other resources that might have the information you need
Most popular trains to and from Palermo Centrale and Florence Santa Maria Novella
Most popular train connections to Palermo Centrale
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