Florence Santa Maria Novella to Palermo Centrale train with Intercity Notte

Tue, Jul 28
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The cheapest and fastest trains from Florence Santa Maria Novella to Palermo Centrale

Showing times and prices for Jul 28

Cheapest price

$125

Average price

$150

Fastest journey

13 h 51 m

Average duration

15 h 28 m

Trains per day

3

Distance

655 km

Cheap tickets

The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence Santa Maria Novella to Palermo Centrale will cost around $150 if you buy it on the day, but the cheapest tickets can be found for only $125.

Fast trains

It's difficult to get from Florence Santa Maria Novella to Palermo Centrale without transferring at least 2 times.

  • RegionaleRegionale 18255+IntercityIntercity 501 · Intercity 727
    5:35 AM17h26
    Florence Santa Maria Novella
    11:01 PMPalermo Centrale
    $1251One-way
    2 transfers
  • TrenitaliaBUS FR403+FrecciarossaFRECCIAROSSA 9519+IntercityIntercity 727
    9:10 AM13h51
    Florence Santa Maria Novella
    11:01 PMPalermo Centrale
    $1481One-way
    2 transfers
  • TrenitaliaBUS FR427+FrecciarossaFRECCIAROSSA 9555+Intercity NotteInterCityNotte 1955
    6:10 PM15h08
    Florence Santa Maria Novella
    9:18 AMPalermo Centrale
    $1761One-way
    2 transfers

Travel Information

Compare train, bus, flight, and ferry for Florence Santa Maria Novella to Palermo Centrale

Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Palermo Centrale among Omio's users. If you are prioritising price take the ferry with prices starting from $44. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a ferry costs an average of $44, and a train costs an average of $77.

Distance: 406 miles (655 km)

Compare train with

Most popular
Train
Bus
Flight
Ferry
Driving

$116

Average price

$55

Average price

$79

Average price

$49

Average price

Cheapest

$63

Average price

(fuel + tolls)

13h 10m

Average total duration

12h 40m

Onboard

+

30m

Additional time*

16h 47m

Average total duration

16h 17m

Onboard

+

30m

Additional time*

4h 42m

Average total duration

Fastest

1h 42m

Onboard

+

3h 0m

Additional time*

21h 0m

Average total duration

20h 0m

Onboard

+

1h 0m

Additional time*

24h 14m

Average total duration

(door-to-door)

Intercity Notte

Most popular train company

FlixBus

Most popular bus company

Volotea

Most popular airline

Grimaldi

Most popular ferry company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence Santa Maria Novella to Palermo Centrale is a ferry with an average price of $49 (€49).

This is compared to other travel options from Florence Santa Maria Novella to Palermo Centrale:

A ferry is $7 (€7) less than a bus for this route with tickets for a bus from Florence Santa Maria Novella to Palermo Centrale costing on average $55 (€55).

A ferry is $30 (€30) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Palermo Centrale costing on average $79 (€79).

A ferry is $68 (€68) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Palermo Centrale costing on average $116 (€116).

The fastest way to travel from Florence Santa Maria Novella to Palermo Centrale is by flight with an average journey time of 1h 42m.

Other travel options to Palermo Centrale take longer:

Train takes on average 12h 40m.

Bus takes on average 16h 17m.

Ferry takes on average 20h 0m.

It's helpful to compare your options as there are 4 ways to travel between Florence Santa Maria Novella and Palermo Centrale including taking a train, bus, flight, and ferry.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Palermo Centrale among Omio's users.
Take the train. It's meaningfully faster than driving, and the time saved usually justifies the price.

You'll arrive about 11h 34m sooner (12h 40m by train vs 24h 14m by car). Tickets start at around $116 (€116) compared to roughly $63 (€63) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.

Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.

Live departures

Florence Santa Maria Novella to Palermo Centrale train times

The table below shows live departures for Florence Santa Maria Novella to Palermo Centrale trains for tomorrow, Tuesday, July 28. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
RegionaleRegionale 18255+IntercityIntercity 501 · Intercity 7275:35 AM Florence Santa Maria Novella
17h26
11:01 PM Palermo Centrale2 transfers
TrenitaliaBUS FR403+FrecciarossaFRECCIAROSSA 9519+IntercityIntercity 7279:10 AM Florence Santa Maria Novella
13h51
11:01 PM Palermo Centrale2 transfers
TrenitaliaBUS FR427+FrecciarossaFRECCIAROSSA 9555+Intercity NotteInterCityNotte 19556:10 PM Florence Santa Maria Novella
15h08
9:18 AM Palermo Centrale2 transfers

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence Santa Maria Novella to Palermo Centrale by train, bus, flight, or ferry

Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Aug 03

Why should you book Florence Santa Maria Novella to Palermo Centrale trains with Omio?

Intercity Notte as well as Intercity, Italo, Frecciargento, Frecciarossa and more offer trains services from Florence Santa Maria Novella to Palermo Centrale.
Omio is the only official third party seller for Intercity Notte tickets.

Why book with Omio vs Intercity Notte?

  • Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Florence Santa Maria Novella to Palermo Centrale.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Florence Santa Maria Novella to Palermo Centrale.

Journey information

Overview: Train from Florence Santa Maria Novella to Palermo Centrale

ItalyItaly
ItalyItaly
Icon of train

Trains from Florence Santa Maria Novella to Palermo Centrale run on average 6 times per day, taking around 12h 40m. Cheap train tickets for this journey start at $77 (€77) but you can travel from only $15 (€15) by bus.

The earliest train runs at 03:35, the last at 23:40. The fastest train covers the 406 miles (655 km) distance in 12h 44m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $15 (€15)
Distance
406 miles (655 km)
Average train duration
12h 40m
Cheapest ticket price
$77 (€77)
Trains per day
6
Fastest train
12h 44m
First train
3:35 AM
Last train
11:40 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Oct - Dec
Busiest Day
Mon
Least Busy Day
Mon
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $15 (€15)

Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Florence Santa Maria Novella to Palermo Centrale trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Florence Santa Maria Novella and Palermo Centrale from $15 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Intercity Notte

About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Intercity Notte frequency
3 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
17h 13m
Cheapest Price
$77 (€77)
Intercity frequency
4 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
14h 7m
Cheapest Price
$105 (€105)
Italo frequency
1 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Learn more about Italo

Frecciargento

About
Frecciargento is a high-speed train service operated by Trenitalia, the national railway company of Italy. It runs on the most popular routes throughout the country, connecting major cities such as Rome, Milan, Florence, and Venice. Frecciargento trains offer a comfortable and convenient way to travel, with a range of ticket types available, including Economy, Standard, and Business. Onboard facilities include air-conditioning, power sockets, and free Wi-Fi. Frecciargento trains are fast and reliable, with journey times of up to four hours between Rome and Milan. They are a great way to explore Italy in style and comfort.
Luggage & cancellation policy
Frecciargento frequency
1 a day
Luggage included
1 carry-on bag and 1 piece of luggage included
Luggage storage
Overhead racks, luggage areas at end of carriages, between seats
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Bar-bistro service with snacks, drinks, and light meals. At-seat service in First Class
Seat reservation
Seat reservation included in ticket price for all classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Learn more about Frecciargento

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
12h 44m
Cheapest Price
$99 (€99)
Frecciarossa frequency
1 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Learn more about Frecciarossa

FAQs: Trains from Florence Santa Maria Novella to Palermo Centrale

Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Florence Santa Maria Novella to Palermo Centrale can vary. The cheapest ticket starts at $77 (€77), while the average price is around $116 (€116).
The train from Florence Santa Maria Novella to Palermo Centrale takes 12h 44m and runs 6 per day.
The first train from Florence Santa Maria Novella to Palermo Centrale leaves at 3:35 AM.
The distance by train from Florence Santa Maria Novella to Palermo Centrale is 406 miles (655 km).
The last train from Florence Santa Maria Novella to Palermo Centrale leaves at 11:40 PM.
Yes, there is a high-speed train from Florence Santa Maria Novella to Palermo Centrale.
There is no direct train service currently available from Florence Santa Maria Novella to Palermo Centrale.
Yes, there is a night train from Florence Santa Maria Novella to Palermo Centrale.
The cheapest way to get from Florence Santa Maria Novella to Palermo Centrale is by bus, with a cost of around $15 (€15).
The train journey from Firenze Santa Maria Novella to Palermo Centrale is scenic, offering views of the Tuscan countryside, the dramatic Apennine Mountains, and the beautiful coastline of southern Italy as you approach Sicily.
A day trip from Firenze Santa Maria Novella to Palermo Centrale is not feasible as the journey takes 12h 44m one way. There are 6 train trips available per day.
Yes, you can take the train from Florence Santa Maria Novella to Palermo Centrale.
Since both Florence Santa Maria Novella and Palermo Centrale are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Palermo Centrale include Cefalù, Santa Flavia, Isola delle Femmine, Campofelice di Roccella, Punta Raisi.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Palermo Centrale among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Florence Santa Maria Novella to Palermo Centrale

Most Florence Santa Maria Novella to Palermo Centrale trains use the Firenze Santa Maria Novella to Enna station pair. Use this guide to compare Florence Santa Maria Novella and Palermo Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Florence
Arrival train stations in Sicily
Firenze Santa Maria NovellaPiazza della Stazione, 1, 50123 Florence, Italy+39 0552352595WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Firenze Santa Maria Novella from Florence city centre

Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:

TramT2 · 4m · $2 · every ~21 min

Firenze Santa Maria Novella train station facilities and services

Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more

Wi-Fi and ATMs

Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.

Tickets and information

The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.

Luggage and lost property

Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.

Parking, taxis and toilets

Available at Firenze Santa Maria Novella: Parking, Taxis, WC.

Bike and car services

Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.

Shops, hotels and contact

Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.

More about Firenze Santa Maria Novella

More options for your journey from Florence Santa Maria Novella to Palermo Centrale

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