- Must visit
Gutenberg Museum
One of the world’s leading museums of printing and book culture, dedicated to Johannes Gutenberg and the history of movable type.
Omio recommends booking the train as it is the most popular option from Osnabrück to Mainz among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a train which can get you there in 4h 7m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $72, and a train costs an average of $19.
Distance: 158 miles (255 km)
Most popular Train | Bus | Driving |
|---|---|---|
$109 Average price | $97 Average price Cheapest | $60 Average price (fuel + tolls) |
4h 37m Average total duration Fastest 4h 7m Onboard + 30m Additional time* | 16h 35m Average total duration 16h 5m Onboard + 30m Additional time* | 4h 11m Average total duration (door-to-door) |
0.1 - 0.2kg CO2 emissions Lowest | 0.3 - 0.6kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Osnabrück to Mainz:
A bus is $12 (€10) less than a train for this route with tickets for a train from Osnabrück to Mainz costing on average $109 (€89).
Other travel options to Mainz take longer:
Bus takes on average 16h 5m.
You'll arrive about 4m sooner (4h 7m by train vs 4h 11m by car). Tickets start at around $109 (€89) compared to roughly $60 (€49) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Direct services run with Deutsche Bahn, Deutsche Bahn Intercity (DB IC).
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
The table below shows live departures for Osnabrück to Mainz trains for today, Saturday, June 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:48 PM Osnabrück | 6h14 | 6:02 AM Mainz | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Osnabrück to Mainz run on average 8 times per day, taking around 4h 7m. Cheap train tickets for this journey start at $19 (€16) if you book in advance.
The earliest train runs at 00:01, the last at 23:02. The fastest train covers the 158 miles (255 km) distance in 4h 26m.
Distance 158 miles (255 km) |
Average train duration 4h 7m |
Cheapest ticket price $19 (€16) |
Trains per day 8 |
Fastest train 4h 26m |
First train 12:01 AM |
Last train 11:02 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 2 days |
Discover the best of Mainz — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mainz trip today.
One of the world’s leading museums of printing and book culture, dedicated to Johannes Gutenberg and the history of movable type.
Major regional museum with archaeology, medieval art, paintings, and Roman-era finds, offering one of the best overviews of Rhineland-Palatinate history.
Natural history museum known for regional geology, fossils, biodiversity, and family-friendly exhibitions.
The most atmospheric area for walking, with narrow lanes, historic facades, shops, and many of the city’s best-known sights.
Central square by the cathedral, lively with markets, events, and classic city views that define the heart of Mainz.
Popular old-town street lined with historic buildings, boutiques, and photo-friendly urban scenery.
A Rheinhessen cheese spread made with fresh cheese, quark, paprika, and spices, traditionally served with pretzels in wine taverns.
A classic Mainz snack of bread roll, sausage, and local wine, strongly associated with everyday life and regional wine culture.
A pungent sour milk cheese marinated with onions and vinegar, popular across the Rhine-Main region and commonly enjoyed with bread.
Established fine dining restaurant with a strong reputation for refined seasonal cuisine and polished service.
Traditional Mainz wine tavern known for local specialties, regional wines, and a classic cozy atmosphere.
A well-known restaurant in a historic former church hall, serving German and regional dishes in a striking atmospheric setting.
Prices are moderate by German standards. Casual dining is reasonable, while hotels and central restaurants cost more.
Service is usually included. Round up in cafés and taxis; tip about 5-10% in restaurants for good service, often by stating the total when paying.
Official public transport app
Mainz Hbf, Mainz -> Schillerplatz, Mainz
Find answers to the most common questions about traveling from Osnabrück to Mainz by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mainz, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need