- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$40
Average price
$74
Fastest journey
4 h 51 m
Average duration
5 h 21 m
Trains per day
12
Distance
336 km
The best way to find a cheap train ticket from Montepulciano station to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Montepulciano station to Milan Centrale will cost around $74 if you buy it on the day, but the cheapest tickets can be found for only $40.
It's difficult to get from Montepulciano station to Milan Centrale without transferring at least 2 times.
Regionale 19087+
Intercity 596
Regionale 19089 · Regionale Veloce 4106+
FRECCIAROSSA 9592
Regionale 18852 · Regionale Veloce 4058+
FRECCIAROSSA 9560
Regionale 19075+
Intercity 590
Regionale 19099+
InterCityNotte 774 · InterCityNotte 758
Regionale 19065 · Regionale 18746+
FRECCIAROSSA 9516
Regionale 19072 · Regionale 18278+
FRECCIAROSSA 9520
Regionale 18852 · Regionale Veloce 4058+
FRECCIAROSSA 9560
Regionale 19075+
Intercity 590+
FRECCIAROSSA 9544
Regionale 19083+
Intercity 592+
FRECCIAROSSA 9660Omio recommends booking the train as it is the most popular option from Montepulciano station to Milan Centrale among Omio's users. If you are prioritising price take the train with prices starting from $42. For those with little time consider booking a flight which can get you there in 1h 10m. The ticket price range depends on the travel mode: a train costs an average of $42, and a flight costs an average of $252.
Distance: 208 miles (336 km)
Most popular Train | Flight | Driving |
|---|---|---|
$63 Average price Cheapest | $336 Average price | $83 Average price (fuel + tolls) |
5h 27m Average total duration 4h 57m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* | 4h 16m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Montepulciano station to Milan Centrale:
A train is $273 (€224) less than a flight for this route with tickets for a flight from Montepulciano station to Milan Centrale costing on average $336 (€275).
Other travel options to Milan Centrale take longer:
Train takes on average 4h 57m.
Tickets start at around $63 (€51) compared to roughly $83 (€68) in fuel and tolls — a saving of about $20 (€17). The journey takes 4h 57m versus 4h 16m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Montepulciano station to Milan Centrale trains for today, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 19067 · Regionale Veloce 4094+ FRECCIAROSSA 9520 | 7:10 AM Montepulciano station | 5h40 | 12:50 PM Milan Centrale | 2 transfers | |
Regionale 19069 · Regionale Veloce 4098+ FRECCIAROSSA 9532 | 9:12 AM Montepulciano station | 6h38 | 3:50 PM Milan Centrale | 2 transfers | |
Regionale 19073+ Intercity 588+ FRECCIAROSSA 9584 | 11:12 AM Montepulciano station | 5h38 | 4:50 PM Milan Centrale | 2 transfers | |
Regionale 19073+ Intercity 588 · Intercity 608 | 11:12 AM Montepulciano station | 6h33 | 5:45 PM Milan Centrale | 2 transfers | |
Regionale 19081+ Intercity 592+ FRECCIAROSSA 9660 | 3:06 PM Montepulciano station | 6h24 | 9:30 PM Milan Centrale | 2 transfers | |
Regionale 19081+ Intercity 592+ Regionale Veloce TTPER 1712 | 3:06 PM Montepulciano station | 7h54 | 11:00 PM Milan Centrale | 2 transfers | |
Regionale 19085 · Regionale Veloce 4106+ FRECCIAROSSA 9592 | 5:14 PM Montepulciano station | 6h36 | 11:50 PM Milan Centrale | 2 transfers | |
Regionale 19097+ InterCityNotte 774+ Regionale Veloce TTPER 2454 | 9:13 PM Montepulciano station | 10h47 | 8:00 AM Milan Centrale | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Montepulciano station to Milan Centrale run on average 12 times per day, taking around 4h 57m. Cheap train tickets for this journey start at $42 (€34) if you book in advance.
The earliest train runs at 03:38, the last at 15:55. The fastest train covers the 208 miles (336 km) distance in 5h 55m.
Distance 208 miles (336 km) |
Average train duration 4h 57m |
Cheapest ticket price $42 (€34) |
Trains per day 12 |
Fastest train 5h 55m |
First train 3:38 AM |
Last train 3:55 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Italy’s largest science museum, featuring Leonardo-inspired displays, transport collections, and interactive exhibits in a former monastery.
A major museum of 20th-century Italian art facing Piazza del Duomo, especially noted for Futurist works and its central location.
Milan’s central square and the city’s main gathering point, ideal for first-time visitors and iconic city views.
A charming historic district known for elegant streets, art atmosphere, boutiques, and a classic Milanese walking experience.
Milan’s canal district, very popular for waterside walks, photos, and lively urban atmosphere, especially in the evening.
Milan’s signature saffron risotto, rich with butter and cheese, celebrated for its golden color and elegant, comforting flavor.
A classic Milanese breaded veal cutlet, traditionally cooked in butter and prized as one of the city’s most iconic dishes.
Braised veal shank, often served with risotto alla Milanese, valued for its tender meat and rich marrow-filled sauce.
Long-standing fine dining destination and one of Milan’s best-known vegetarian restaurants, refined and creative in style.
Well-known Milanese restaurant with a modern approach to Lombard classics such as risotto and mondeghili in a stylish setting.
Historic traditional trattoria known for classic Milanese dishes, old-world atmosphere, and a strong local reputation.
Prices are above the Italian average, especially near the station. Casual meals are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-5 for good service. Taxis can be rounded up.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Montepulciano station to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

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