The cheapest and fastest trains from Interlaken to Florence Santa Maria Novella
Cheapest price
$150
Average price
$160
Fastest journey
6 h 23 m
Average duration
6 h 59 m
Trains per day
3
Distance
418 km
The best way to find a cheap train ticket from Interlaken to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Interlaken to Florence Santa Maria Novella will cost around $160 if you buy it on the day, but the cheapest tickets can be found for only $150.
It's difficult to get from Interlaken to Florence Santa Maria Novella without transferring at least 4 times.
2:12 PM6h23Interlaken8:35 PMFlorence Santa Maria Novella$1501One-way4 transfers
4:12 PM6h23Interlaken10:35 PMFlorence Santa Maria Novella$1501One-way4 transfers
6:04 AM8h11Interlaken2:15 PMFlorence Santa Maria Novella$1791One-way4 transfers
2:12 PM6h23Interlaken8:35 PMFlorence Santa Maria Novella$1501One-way4 transfers
4:12 PM6h23Interlaken10:35 PMFlorence Santa Maria Novella$1501One-way4 transfers
6:04 AM8h11Interlaken2:15 PMFlorence Santa Maria Novella$1791One-way4 transfers
Travel Information
Compare bus, train, and flight for Interlaken to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Interlaken to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $95. For those with little time consider booking a flight which can get you there in 1h 12m. The ticket price range depends on the travel mode: a bus costs an average of $95, and a flight costs an average of $98.
Distance: 259 miles (418 km)
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$161 Average price | $239 Average price | $100 Average price Cheapest | $220 Average price (fuel + tolls) |
6h 19m Average total duration 5h 49m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 1h 12m Onboard + 3h 0m Additional time* | 16h 25m Average total duration 15h 55m Onboard + 30m Additional time* | 6h 53m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Interlaken to Florence Santa Maria Novella:
A bus is $61 (€49) less than a train for this route with tickets for a train from Interlaken to Florence Santa Maria Novella costing on average $161 (€129).
A bus is $139 (€111) less than a flight for this route with tickets for a flight from Interlaken to Florence Santa Maria Novella costing on average $239 (€191).
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 5h 49m.
Bus takes on average 15h 55m.
The journey is about 1h 4m faster (5h 49m by train vs 6h 53m by car) and roughly $59 (€47) cheaper once you factor in fuel and tolls ($161 (€129) vs $220 (€176)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Live departures
Interlaken to Florence Santa Maria Novella train times
The table below shows live departures for Interlaken to Florence Santa Maria Novella trains for today, Thursday, May 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
RE 9 4223 | 4223 · RE 1 4273 | 4273+ EuroCity 45+ Intercity 679 | 1:32 PM Interlaken West | 10h18 | 11:50 PM Florence Santa Maria Novella | 4 transfers | |
RE 9 4223 | 4223 · RE 1 4273 | 4273+ EuroCity 45+ FRECCIAROSSA 9559 | 1:32 PM Interlaken West | 6h32 | 8:04 PM Florence Santa Maria Novella | 3 transfers | |
RE 9 4223 | 4223 · EC 65 | 65+ EuroCity 45+ FRECCIAROSSA 9559 | 1:32 PM Interlaken West | 6h32 | 8:04 PM Florence Santa Maria Novella | 3 transfers | |
PE GPX 4075 | 4075+ IC 6 971 | 971+ EuroCity 45+ Intercity 679 | 2:12 PM Interlaken West | 9h38 | 11:50 PM Florence Santa Maria Novella | 4 transfers | |
PE GPX 4075 | 4075+ IC 6 971 | 971+ EuroCity 45+ FRECCIAROSSA 9559 | 2:12 PM Interlaken West | 5h52 | 8:04 PM Florence Santa Maria Novella | 3 transfers | |
![]() | 6:04 AM Interlaken | 8h11 | 2:15 PM Florence Santa Maria Novella | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Interlaken to Florence Santa Maria Novella by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Interlaken to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Trenitalia?
- Compare with other providers: On Omio, you can not only buy tickets for Trenitalia, but also compare tickets for the likes of Intercity, SBB, Swiss Federal Railways (SBB CFF FFS) or BLS AG to find the best option for your trip from Interlaken to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Trenitalia with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Interlaken to Florence Santa Maria Novella.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Interlaken to Florence Santa Maria Novella.
Journey information
Overview: Train from Interlaken to Florence Santa Maria Novella
Trains from Interlaken to Florence Santa Maria Novella run on average 11 times per day, taking around 5h 49m. Cheap train tickets for this journey start at $150 (€120) but you can travel from only $95 (€76) by bus.
The earliest train runs at 06:04, the last at 16:12. The fastest train covers the 259 miles (418 km) distance in 6h 23m.
Distance 259 miles (418 km) |
Average train duration 5h 49m |
Cheapest ticket price $150 (€120) |
Trains per day 11 |
Fastest train 6h 23m |
First train 6:04 AM |
Last train 4:12 PM |
Cheapest Month Oct |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Thu |
Train companies: Trenitalia, Intercity, SBB, Swiss Federal Railways (SBB CFF FFS), BLS AG from Interlaken to Florence Santa Maria Novella trainsTrenitalia, Intercity, SBB, Swiss Federal Railways (SBB CFF FFS), BLS AG trains will get you between Interlaken and Florence Santa Maria Novella from $95 (€76). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Trenitalia
Intercity
SBB
Swiss Federal Railways (SBB CFF FFS)
BLS AG
FAQs: Trains from Interlaken to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Interlaken to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Interlaken to Florence Santa Maria Novella
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
More options for your journey from Interlaken to Florence Santa Maria Novella
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