- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$18
Average price
$24
Fastest journey
1 h 44 m
Average duration
1 h 48 m
Trains per day
21
Distance
122 km
The best way to find a cheap train ticket from Genoa Brignole to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Genoa Brignole to Milan Centrale will cost around $24 if you buy it on the day, but the cheapest tickets can be found for only $18.
Of the 21 trains that leave Genoa Brignole for Milan Centrale on Thu, Jun 04, 14 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jun 04 the direct trains cover the 122 km distance in an average of 1 h 48 m but if you time it right, some trains will get you there in just 1 h 44 m .
On Thu, Jun 04 the slowest trains will take 1 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 3044
Regionale Veloce 3032
Regionale Veloce 3016
Regionale 3360 · Regionale Veloce 3019
Regionale Veloce 3040
FRECCIABIANCA 8620
Intercity 662
Regionale 12456+
Intercity 639
Intercity 670
Intercity 666Omio recommends booking the train as it is the most popular option from Genoa Brignole to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $6. For those with little time consider booking a train which can get you there in 1h 51m. The ticket price range depends on the travel mode: a bus costs an average of $6, and a train costs an average of $12.
Distance: 75 miles (122 km)
Most popular Train | Bus | Driving |
|---|---|---|
$18 Average price | $10 Average price Cheapest | $42 Average price (fuel + tolls) |
2h 21m Average total duration Fastest 1h 51m Onboard + 30m Additional time* | 2h 25m Average total duration 1h 55m Onboard + 30m Additional time* | 1h 57m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Genoa Brignole to Milan Centrale:
A bus is $7 (€6) less than a train for this route with tickets for a train from Genoa Brignole to Milan Centrale costing on average $18 (€15).
Other travel options to Milan Centrale take longer:
Bus takes on average 1h 55m.
The journey is about 6m faster (1h 51m by train vs 1h 57m by car) and roughly $25 (€20) cheaper once you factor in fuel and tolls ($18 (€15) vs $42 (€34)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with Intercity, Regionale, Frecciabianca, Frecciarossa, Italo.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Genoa Brignole to Milan Centrale trains for today, Wednesday, June 3. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 12410+ Intercity 635 | 4:40 PM Genoa Brignole | 2h20 | 7:00 PM Milan Centrale | 1 transfer | |
Regionale Veloce 3040 | 5:36 PM Genoa Brignole | 1h59 | 7:35 PM Milan Centrale | 0 transfersDirect | |
Intercity 680 | 6:09 PM Genoa Brignole | 1h56 | 8:05 PM Milan Centrale | 0 transfersDirect | |
FRECCIABIANCA 8620 | 6:56 PM Genoa Brignole | 1h44 | 8:40 PM Milan Centrale | 0 transfersDirect | |
Regionale 12438+ Intercity 681 | 7:05 PM Genoa Brignole | 2h00 | 9:05 PM Milan Centrale | 1 transfer | |
Regionale Veloce 3044 | 7:36 PM Genoa Brignole | 1h59 | 9:35 PM Milan Centrale | 0 transfersDirect | |
Intercity 684 | 8:10 PM Genoa Brignole | 1h50 | 10:00 PM Milan Centrale | 0 transfersDirect | |
Regionale 12456+ Intercity 639 | 9:05 PM Genoa Brignole | 1h50 | 10:55 PM Milan Centrale | 1 transfer | |
Regionale Veloce 2146 · Regionale Veloce 3047 | 9:18 PM Genoa Brignole | 2h17 | 11:35 PM Milan Centrale | 1 transfer | |
| Thursday, June 4 | |||||
Regionale Veloce 3016 | 5:36 AM Genoa Brignole | 1h59 | 7:35 AM Milan Centrale | 0 transfersDirect | |
Intercity 652 | 6:35 AM Genoa Brignole | 1h50 | 8:25 AM Milan Centrale | 0 transfersDirect | |
Regionale 22820+ Intercity 653 | 6:57 AM Genoa Brignole | 2h08 | 9:05 AM Milan Centrale | 1 transfer | |
Regionale 3360 · Regionale Veloce 3019 | 7:35 AM Genoa Brignole | 2h00 | 9:35 AM Milan Centrale | 1 transfer | |
Intercity 658 | 8:10 AM Genoa Brignole | 1h50 | 10:00 AM Milan Centrale | 0 transfersDirect | |
Intercity 662 | 9:09 AM Genoa Brignole | 1h46 | 10:55 AM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 3028 | 11:34 AM Genoa Brignole | 2h01 | 1:35 PM Milan Centrale | 0 transfersDirect | |
Intercity 666 | 12:10 PM Genoa Brignole | 1h50 | 2:00 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 3032 | 1:36 PM Genoa Brignole | 1h59 | 3:35 PM Milan Centrale | 0 transfersDirect | |
Intercity 670 | 2:10 PM Genoa Brignole | 1h50 | 4:00 PM Milan Centrale | 0 transfersDirect | |
Regionale 22854 · Regionale Veloce 3021 | 3:25 PM Genoa Brignole | 2h10 | 5:35 PM Milan Centrale | 1 transfer | |
Intercity 674 | 4:08 PM Genoa Brignole | 1h57 | 6:05 PM Milan Centrale | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Genoa Brignole to Milan Centrale run on average 24 times per day, taking around 1h 51m. Cheap train tickets for this journey start at $12 (€10) but you can travel from only $6 (€5) by bus.
There are 11 trains per day. The earliest train runs at 04:05, the last at 20:05. The fastest train covers the 75 miles (122 km) distance in 1h 44m.
Distance 75 miles (122 km) |
Average train duration 1h 51m |
Cheapest ticket price $12 (€10) |
Trains per day 24 |
Direct trains 11 |
Fastest train 1h 44m |
First train 4:05 AM |
Last train 8:05 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Thu |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
The museum site hosting Leonardo da Vinci’s Last Supper at Santa Maria delle Grazie, one of Milan’s most sought-after cultural visits.
A leading museum of 20th-century Italian art overlooking Piazza del Duomo, with strong Futurist and modern collections.
Milan’s main square and the city’s symbolic heart, ideal for first-time visitors, landmark views, and people-watching.
A charming historic neighborhood of narrow streets, elegant buildings, galleries, and boutiques, popular for strolling and atmosphere.
Milan’s canal-side area known for scenic walks, bridges, and lively urban character, especially photogenic in the evening.
Creamy saffron risotto, the signature dish of Milan, prized for its rich flavor and golden color.
Breaded veal cutlet fried in butter, a classic Milanese main course with a crisp exterior and tender meat.
Braised veal shanks, often served with risotto, loved in Milan for its deep, slow-cooked flavor.
Elegant fine-dining venue at Excelsior Hotel Gallia near Milano Centrale, known for upscale Italian cuisine.
Established Michelin-starred restaurant celebrated for creative vegetarian cuisine and a distinctive fine-dining experience.
Well-known modern Milanese restaurant serving refined Lombard classics in a stylish, contemporary setting.
Generally pricier than many Italian cities, especially near the station. Budget eats are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto charge. Tipping is not mandatory, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Genoa Brignole to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

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