- Must visit
Galleria degli Uffizi
Florence’s flagship art museum, famous for Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Cheapest price
$88
Average price
$129
Fastest journey
7 h 55 m
Average duration
8 h 7 m
Trains per day
15
Distance
652 km
The best way to find a cheap train ticket from Brindisi to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brindisi to Florence Santa Maria Novella will cost around $129 if you buy it on the day, but the cheapest tickets can be found for only $88.
It's difficult to get from Brindisi to Florence Santa Maria Novella without transferring at least once.
InterCityNotte 754+
Regionale 17807
Intercity 614+
Regionale 17853 · Regionale 18539
Intercity 608+
Regionale 17835 · Regionale 18493
Intercity 612 · Intercity 599
Intercity 610 · Intercity 594+
Regionale 18312
FRECCIAROSSA 9808 · FRECCIAROSSA 8529
FRECCIAROSSA 8818 · FRECCIAROSSA 8519
FRECCIAROSSA 8824 · FRECCIAROSSA 8525
FRECCIAROSSA 8816 · FRECCIAROSSA 9421
FRECCIAROSSA 8814 · FRECCIAROSSA 8419Omio recommends booking the train as it is the most popular option from Brindisi to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a flight which can get you there in 2h 5m. The ticket price range depends on the travel mode: a bus costs an average of $35, and a train costs an average of $64.
Distance: 405 miles (652 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$92 Average price | $58 Average price Cheapest | $81 Average price | $227 Average price (fuel + tolls) |
9h 1m Average total duration 8h 31m Onboard + 30m Additional time* | 10h 55m Average total duration 10h 25m Onboard + 30m Additional time* | 5h 5m Average total duration Fastest 2h 5m Onboard + 3h 0m Additional time* | 8h 11m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Brindisi to Florence Santa Maria Novella:
A bus is $24 (€19) less than a flight for this route with tickets for a flight from Brindisi to Florence Santa Maria Novella costing on average $81 (€67).
A bus is $34 (€28) less than a train for this route with tickets for a train from Brindisi to Florence Santa Maria Novella costing on average $92 (€75).
Other travel options to Florence Santa Maria Novella take longer:
Train takes on average 8h 31m.
Bus takes on average 10h 25m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Frecciarossa.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Brindisi to Florence Santa Maria Novella trains for today, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:53 PM Brindisi | 11h09 | 6:02 AM Florence Santa Maria Novella | 0 transfersDirect | |
| Monday, June 22 | |||||
Regionale 23572+ FRECCIAROSSA 9806 · FRECCIAROSSA 9415 | 4:00 AM Brindisi station | 9h39 | 1:39 PM Florence Santa Maria Novella | 2 transfers | |
FRECCIAROSSA 8814 · FRECCIAROSSA 8419 | 6:17 AM Brindisi station | 8h22 | 2:39 PM Florence Santa Maria Novella | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Brindisi to Florence Santa Maria Novella run on average 16 times per day, taking around 8h 31m. Cheap train tickets for this journey start at $64 (€53) but you can travel from only $24 (€20) by flight.
The earliest train runs at 04:47, the last at 20:40. The fastest train covers the 405 miles (652 km) distance in 7h 42m.
Distance 405 miles (652 km) |
Average train duration 8h 31m |
Cheapest ticket price $64 (€53) |
Trains per day 16 |
Fastest train 7h 42m |
First train 4:47 AM |
Last train 8:40 PM |
Cheapest Month Jun |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Thu |
Discover the best of Firenze Santa Maria Novella — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Firenze Santa Maria Novella trip today.
Florence’s flagship art museum, famous for Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Best known for Michelangelo’s David, plus important Florentine paintings and sculpture. Advance booking is commonly needed.
Vast former Medici palace housing several museum collections, including Palatine Gallery interiors and royal apartments.
The symbolic heart of Florence, packed with the cathedral complex and some of the city’s most photographed architecture.
Historic civic square filled with monumental sculpture and framed by Palazzo Vecchio and the Loggia dei Lanzi.
The classic panoramic terrace over Florence, especially popular at sunset and widely featured in travel photography and social media.
The iconic Florentine T-bone steak, cut very thick from Chianina beef and grilled rare over coals. It is one of the city’s most famous traditional dishes.
A classic Florentine street food made from the fourth stomach of the cow, simmered in broth and usually served in a bread roll with green sauce or spicy oil.
A hearty Tuscan soup of bread, cannellini beans, and vegetables, especially black cabbage. It is a rustic peasant dish strongly associated with Florence and Tuscany.
Established Michelin-starred restaurant offering refined contemporary Tuscan cuisine in an elegant setting within central Florence.
Long-established local favorite known for its intimate old-school atmosphere and classic dishes such as butter chicken and Tuscan comfort food.
Historic, no-frills Florentine trattoria near the central market, famous for traditional Tuscan dishes including steak, ribollita, and hearty daily specials.
Moderate for Italy: cafés and casual meals are reasonable, but hotels and tourist-area dining near the station cost more.
Service is often included or covered by coperto. Tipping is not obligatory; round up or leave EUR 1-2 at cafés, 5-10% for great restaurant service, and round up taxis.
Official public transport app
Firenze Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Brindisi to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

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