Journey information
Overview: Madrid to Santiago flight
Flights from Madrid to Santiago depart on average 61 times per day, taking around 15h 54m. Cheap flight tickets for this journey start at $542 (€431) if you book in advance.
There are 6 flights per day. The earliest flight runs at 00:05, the last at 23:55. The fastest flight covers the 6649 miles (10701 km) distance in 13h 15m. February is the cheapest month to fly.
Distance 6649 miles (10701 km) |
Average flight duration 15h 54m |
Cheapest ticket price $542 (€431) |
Flights per day 61 |
Direct flights 6 |
Fastest flight 13h 15m |
Cheapest month February |
First flight 00:05 |
Last flight 23:55 |
The cheapest and fastest flights from Madrid to Santiago
Cheapest price
$686
Average price
$758
Fastest journey
13 h 15 m
Average duration
14 h 12 m
Flights per day
5
Distance
10701 km
The best way to find a cheap flight ticket from Madrid to Santiago is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Santiago will cost around $758 if you buy it on the day, but the cheapest tickets can be found for only $686.
Of the 5 flights that leave Madrid for Santiago onFri, Feb 27, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 27 the direct flights cover the 10701 km distance in an average of 14 h 12 m but if you time it right, some flights will get you there in just 13 h 15 m .
On Fri, Feb 27 the longest flights will take 17 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Live departures
Madrid to Santiago flight times
The table below shows live departures for Madrid to Santiago flights for today, Thursday, February 26. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:50 PM Madrid | 22h15 | 2:05 PM Santiago | 0 transfersDirect | |
![]() | 10:59 PM Madrid | 13h21 | 12:20 PM Santiago | 0 transfersDirect | |
| Friday, February 27 | |||||
![]() | 9:50 AM Madrid | 17h40 | 3:30 AM Santiago | 0 transfersDirect | |
![]() | 11:55 AM Madrid | 13h20 | 1:15 AM Santiago | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
How far in advance should I book flight tickets from Madrid to Santiago?
Compare prices and tickets Madrid to Santiago by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 27
Feb 28
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Why should you book Madrid to Santiago flights with Omio?
Why book with Omio vs Iberia?
- Compare with other providers: On Omio, you can not only buy tickets for Iberia, but also compare tickets for the likes of LATAM Airlines, Avianca - Aerovias Nacionales de Colombia, Aerolineas Argentinas or Air France to find the best option for your trip from Madrid to Santiago.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Kayak, Trip or Edreams?
- Compare with other providers: On Omio, you can also compare tickets for the likes of LATAM Airlines, Avianca - Aerovias Nacionales de Colombia, Aerolineas Argentinas or Air France to find the best option for your trip from Madrid to Santiago.
Airlines: Iberia, LATAM Airlines, Avianca - Aerovias Nacionales de Colombia, Aerolineas Argentinas, Air France, Airzena, Air Europa, British Airways, KLM from Madrid to SantiagoFind the best flights between Madrid to Santiago with Omio's travel partners Iberia, LATAM Airlines, Avianca - Aerovias Nacionales de Colombia, Aerolineas Argentinas, Air France, Airzena, Air Europa, British Airways, KLM from $542 (€431). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Avianca - Aerovias Nacionales de Colombia
Aerolineas Argentinas
Air France
British Airways
Iberia
LATAM Airlines
Air Europa
KLM
Airzena
FAQs: Madrid to Santiago Flight
Find answers to the most common questions about traveling from Madrid to Santiago by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santiago, this guide helps you travel smarter and with confidence.

- Fiesta de la Vendimia, a vibrant wine harvest festival celebrating Chile's winemaking heritage with tastings, music, and cultural events
- Santiago a Mil, an international theater festival featuring performances from around the world in various venues across the city
- Fiestas Patrias, Chile's national celebrations with parades, traditional food, and folk music honoring the country's independence.
- Fiestas Patrias, vibrant national celebrations with parades, traditional music, and delicious food
- New Year’s Day, lively festivities and fireworks to welcome the new year in a warm climate
- Easter, a time for cultural and religious observances with beautiful processions.
popular airports
Popular airports from Madrid to Santiago
- Free Wi-Fi available throughout the airport.
- Shops in all terminals, including duty-free and fashion brands.
- Parking available at all terminals, approximately 2.5€ per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in all terminals, including VIP lounges.
- Located in Terminal 1, 2, and 4.
- Metro: Line 8
- Bus: Lines 101, 200, Exprés-203
- Train: Cercanías C1, C10
- Free Wi-Fi available throughout the airport.
- Shops include duty-free and local Chilean products, located in both terminals.
- Parking available in several lots, approximately 1.7€ (CLP 1,500) per hour.
- Restaurants available in both domestic and intertiol terminals; options include fast food and Chilean cuisine.
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby include Holiday Inn Santiago Airport, within walking distance.
- Showers available in VIP lounges; access may require a lounge pass or fee.
- Several lounges available, including LATAM and American Airlines lounges.
- Lost and Found located in the arrivals area.
- Car rental services available from major companies like Hertz and Avis.
- Bus Centropuerto, Pajaritos Station, 19 km
More options for your journey from Madrid to Santiago
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