Chicago, IL CHI to Jefferson City, MO JEF flight with American Airlines

Tue, Sep 15
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Journey information

Overview: Chicago, IL to Jefferson City, MO flight

USAUSA
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Icon of flight

Flights from Chicago, IL to Jefferson City, MO depart on average 30 times per day, taking around 4h 44m. Cheap flight tickets for this journey start at $227 but you can travel from only $58 by bus.

There are 2 flights per day. The earliest flight runs at 00:10, the last at 23:05. The fastest flight covers the 328 miles (529 km) distance in 1h 26m. October is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $58
Distance
328 miles (529 km)
Average flight duration
4h 44m
Cheapest ticket price
$227
Flights per day
30
Direct flights
2
Fastest flight
1h 26m
First flight
12:10 AM
Last flight
11:05 PM
Cheapest Month
Oct
Cheapest Day
Wed
High Season
Apr - Jun
Low Season
Jul - Sep
Busiest Day
Mon
Least Busy Day
Mon
Best time to book
35 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $58

The cheapest and fastest flights from Chicago, IL to Jefferson City, MO

Showing times, prices and bookable tickets for Sep 15

Cheapest price on Sep 15

$411

Average ticket price on Sep 15

$655

Fastest journey on Sep 15

1 h 31 m

Average journey duration on Sep 15

1 h 34 m

Flights on Sep 15

42

Distance

529 km

Cheap tickets

The best way to find a cheap flight ticket from Chicago, IL to Jefferson City, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Chicago, IL to Jefferson City, MO will cost around $655 if you buy it on the day, but the cheapest tickets can be found for only $411.

Fast flights

On Tue, Sep 15, we found 42 flights from Chicago, IL to Jefferson City, MO, including 6 direct services.

On Tue, Sep 15 the direct flights cover the 529 km distance in an average of 1 h 34 m but if you time it right, some flights will get you there in just 1 h 31 m .

On Tue, Sep 15 the longest flights will take 1 h 39 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • envoy airAA3394
    8:24 AM1h32
    O'Hare International Airport
    9:56 AMColumbia Regional Airport
    $4111One-way
    0 transfers
  • envoy airAA3696
    7:13 PM1h33
    O'Hare International Airport
    8:46 PMColumbia Regional Airport
    $4111One-way
    0 transfers
  • envoy airAA3398
    4:31 PM1h31
    O'Hare International Airport
    6:02 PMColumbia Regional Airport
    $4111One-way
    0 transfers
  • American AirlinesAA1106+envoy airAA3402
    11:00 AM5h19
    O'Hare International Airport
    4:19 PMColumbia Regional Airport
    $4211One-way
    1 transfer
  • American AirlinesAA2896+envoy airAA3416
    6:00 AM5h29
    O'Hare International Airport
    11:29 AMColumbia Regional Airport
    $4211One-way
    1 transfer

Travel Information

Compare train, bus, and flight for Chicago, IL to Jefferson City, MO

Omio recommends booking the train as it is the most popular option from Chicago, IL to Jefferson City, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $106 For those with little time, consider booking a flight, which has an average total journey time of 6h 44m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $106, while a flight costs an average of $669.

Distance: 328 miles (529 km)

Compare flight with

Flight
Most popular
Train
Bus
Driving

$669

Average price

$106

Average price

$106

Average price

Cheapest

$81

Average price

(fuel + tolls)

6h 44m

Average total duration

Fastest

4h 44m

Onboard

+

2h 0m

Additional time*

7h 59m

Average total duration

7h 29m

Onboard

+

30m

Additional time*

12h 6m

Average total duration

11h 36m

Onboard

+

30m

Additional time*

5h 59m

Average total duration

(door-to-door)

-

CO2 emissions

0.2 - 0.5kg

CO2 emissions

Lowest

0.5 - 1.3kg

CO2 emissions

-

CO2 emissions

American Airlines

Most popular airline

Amtrak

Most popular train company

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Chicago, IL to Jefferson City, MO is a bus with an average price of $106.

This is compared to other travel options from Chicago, IL to Jefferson City, MO:

A bus is $0.06 less than a train for this route with tickets for a train from Chicago, IL to Jefferson City, MO costing on average $106.

A bus is $562 less than a flight for this route with tickets for a flight from Chicago, IL to Jefferson City, MO costing on average $669.

The fastest way to travel from Chicago, IL to Jefferson City, MO is by flight with an average journey time of 4h 44m.

Other travel options to Jefferson City, MO take longer:

Train takes on average 7h 29m.

Bus takes on average 11h 36m.

It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and Jefferson City, MO including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Chicago, IL to Jefferson City, MO among Omio's users.

Live departures

Chicago, IL to Jefferson City, MO flight times

The table below shows live departures for Chicago, IL to Jefferson City, MO flights for today, Monday, September 14. You can also manually refresh the results below to see updated flight journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
UnitedUA1885 · UA57978:40 AM O'Hare International Airport
11h59
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA2080+envoy airAA36188:59 AM O'Hare International Airport
13h09
10:08 PM Columbia Regional Airport1 transfer
UnitedUA53279:00 AM O'Hare International Airport
1h39
10:39 AM Columbia Regional Airport0 transfersDirect
American AirlinesAA1459+envoy airAA34029:40 AM O'Hare International Airport
6h39
4:19 PM Columbia Regional Airport1 transfer
American AirlinesAA1459+envoy airAA39289:40 AM O'Hare International Airport
10h32
8:12 PM Columbia Regional Airport1 transfer
UnitedUA536 · UA579710:55 AM O'Hare International Airport
9h44
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA1106+envoy airAA340211:00 AM O'Hare International Airport
5h19
4:19 PM Columbia Regional Airport1 transfer
American AirlinesAA1106+envoy airAA392811:00 AM O'Hare International Airport
9h12
8:12 PM Columbia Regional Airport1 transfer
American AirlinesAA3021+envoy airAA361811:50 AM O'Hare International Airport
10h18
10:08 PM Columbia Regional Airport1 transfer
American AirlinesAA3085+envoy airAA392812:09 PM O'Hare International Airport
8h03
8:12 PM Columbia Regional Airport1 transfer
UnitedUA2809 · UA579712:45 PM O'Hare International Airport
7h54
8:39 PM Columbia Regional Airport1 transfer
UnitedUA448312:50 PM O'Hare International Airport
1h40
2:30 PM Columbia Regional Airport0 transfersDirect
American AirlinesAA1409+envoy airAA36181:19 PM O'Hare International Airport
8h49
10:08 PM Columbia Regional Airport1 transfer
skywest airlinesAA49951:28 PM O'Hare International Airport
1h33
3:01 PM Columbia Regional Airport0 transfersDirect
UnitedUA2324 · UA57971:30 PM O'Hare International Airport
7h09
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA2451+envoy airAA39281:46 PM O'Hare International Airport
6h26
8:12 PM Columbia Regional Airport1 transfer
UnitedUA2803 · UA57972:32 PM O'Hare International Airport
6h07
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA2429+envoy airAA39283:00 PM O'Hare International Airport
5h12
8:12 PM Columbia Regional Airport1 transfer
UnitedUA2769 · UA57973:56 PM O'Hare International Airport
28h43
8:39 PM Columbia Regional Airport1 transfer
UnitedUA2119 · UA57974:26 PM O'Hare International Airport
28h13
8:39 PM Columbia Regional Airport1 transfer
envoy airAA33984:31 PM O'Hare International Airport
1h31
6:02 PM Columbia Regional Airport0 transfersDirect
American AirlinesAA3188+envoy airAA36184:45 PM O'Hare International Airport
5h23
10:08 PM Columbia Regional Airport1 transfer
UnitedUA1974 · UA57975:51 PM O'Hare International Airport
26h48
8:39 PM Columbia Regional Airport1 transfer
envoy airAA36967:13 PM O'Hare International Airport
1h33
8:46 PM Columbia Regional Airport0 transfersDirect
UnitedUA329 · UA57977:50 PM O'Hare International Airport
24h49
8:39 PM Columbia Regional Airport1 transfer
UnitedUA1046 · UA57978:20 PM O'Hare International Airport
24h19
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA2281+envoy airAA34169:15 PM O'Hare International Airport
14h14
11:29 AM Columbia Regional Airport1 transfer
UnitedUA44759:20 PM O'Hare International Airport
1h35
10:55 PM Columbia Regional Airport0 transfersDirect
UnitedUA1161 · UA57979:35 PM O'Hare International Airport
23h04
8:39 PM Columbia Regional Airport1 transfer
Tuesday, September 15
UnitedUA2666 · UA57975:00 AM O'Hare International Airport
15h39
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA760+envoy airAA34025:00 AM O'Hare International Airport
11h19
4:19 PM Columbia Regional Airport1 transfer
American AirlinesAA760+envoy airAA34165:00 AM O'Hare International Airport
6h29
11:29 AM Columbia Regional Airport1 transfer
UnitedUA2806 · UA57976:00 AM O'Hare International Airport
14h39
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA2896+envoy airAA39286:00 AM O'Hare International Airport
14h12
8:12 PM Columbia Regional Airport1 transfer
American AirlinesAA2896+envoy airAA34166:00 AM O'Hare International Airport
5h29
11:29 AM Columbia Regional Airport1 transfer
American AirlinesAA2896+envoy airAA34026:00 AM O'Hare International Airport
10h19
4:19 PM Columbia Regional Airport1 transfer
American AirlinesAA1784+envoy airAA36186:45 AM O'Hare International Airport
15h23
10:08 PM Columbia Regional Airport1 transfer
UnitedUA1217 · UA57977:00 AM O'Hare International Airport
13h39
8:39 PM Columbia Regional Airport1 transfer
American AirlinesAA1360+envoy airAA39287:09 AM O'Hare International Airport
13h03
8:12 PM Columbia Regional Airport1 transfer
American AirlinesAA1360+envoy airAA34027:09 AM O'Hare International Airport
9h10
4:19 PM Columbia Regional Airport1 transfer
American AirlinesAA411+envoy airAA36188:05 AM O'Hare International Airport
14h03
10:08 PM Columbia Regional Airport1 transfer
American AirlinesAA1555+envoy airAA39288:15 AM O'Hare International Airport
11h57
8:12 PM Columbia Regional Airport1 transfer
American AirlinesAA1555+envoy airAA34028:15 AM O'Hare International Airport
8h04
4:19 PM Columbia Regional Airport1 transfer
envoy airAA33948:24 AM O'Hare International Airport
1h32
9:56 AM Columbia Regional Airport0 transfersDirect

This is the last flight of the day.

Find all the dates and times for this journey

Compare prices and tickets Chicago, IL to Jefferson City, MO by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Sep 15
Wed
Sep 16
Thu
Sep 17
Fri
Sep 18
Sat
Sep 19
Sun
Sep 20
Mon
Sep 21

Why should you book Chicago, IL to Jefferson City, MO flights with Omio?

United operates all flights services from Chicago, IL to Jefferson City, MO.
Omio is an official ticket reseller for all your travel options from Chicago, IL to Jefferson City, MO.

Why book with Omio vs United?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare United with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Chicago, IL to Jefferson City, MO.

Why book with Omio over Kayak, Skyscanner or Trip?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Chicago, IL to Jefferson City, MO.

Airlines: American Airlines, United from Chicago, IL to Jefferson City, MOFind the best flights between Chicago, IL to Jefferson City, MO with Omio's travel partners American Airlines, United from $63. We can find you the best deals, schedules and tickets when comparing and booking the best trip.

United

About
United Airlines, established in 1926, is a major U.S. airline headquartered in Chicago, Illinois. Operating an extensive domestic and international network, United serves more destinations than any other airline, connecting travelers across six continents. The airline's eight hubs include Chicago–O'Hare, Denver, Houston–Intercontinental, Los Angeles, Newark, San Francisco, Washington–Dulles, and Guam. As a founding member of the Star Alliance, United offers a comprehensive range of services, including regional flights through United Express, catering to both leisure and business travelers. The airline is committed to sustainability, investing in sustainable aviation fuel and innovative technologies to reduce its environmental impact.
Luggage & cancellation policy
Average United Duration
1h 26m
Cheapest United Price
$249
United frequency
15 a day
Luggage included
Carry-on baggage allowance is 7kg total (2 pieces max. ) for both Choice and Flex fares on United Airlines and Virgin Australia flights.
Additional luggage
Excess baggage fees apply for additional checked luggage beyond the standard allowance.
Luggage storage
Both airlines provide checked baggage services for storing luggage during flights.
Cancellation Policy
Cancellation fees apply per person, per booking, with specific fees for different fare types.
Refund
Not applicable to flights; however, full refunds are available if flights are canceled by the airline.
Pregnant on board
Pregnant passengers are permitted to travel, with specific guidelines and medical certificates required after a certain gestational period.
Unaccompagned minor
Unaccompanied minors are permitted to travel, with specific age restrictions and services provided.
Amenities on board the airplane
Wifi
Food sold onboard
Meals and snacks are included on international flights operated by United Airlines and Virgin Australia.
Seat reservation
Seat selection may incur additional fees, depending on the fare type and airline.
Toilets
USB plugs
Accessibility
United Airlines and Virgin Australia offer services to and within Australia, providing accessible travel options for passengers with mobility needs.
Bikes
Both airlines permit bicycles onboard, with specific guidelines and fees.
Pets
United Airlines and Virgin Australia allow pets onboard, subject to specific policies and fees.
Learn more about United

American Airlines

About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average American Airlines Duration
4h 9m
Cheapest American Airlines Price
$227
American Airlines frequency
18 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Learn more about American Airlines

FAQs: Chicago, IL to Jefferson City, MO Flight

Find answers to the most common questions about traveling from Chicago, IL to Jefferson City, MO by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Jefferson City, MO, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from Chicago, IL to Jefferson City, MO can start from as little as $227 when you book in advance. The average flight ticket price for Chicago, IL to Jefferson City, MO is $669 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Chicago, IL to Jefferson City, MO is 1h 26m to travel the 328 miles (529 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Chicago, IL to Jefferson City, MO leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Chicago, IL to Jefferson City, MO leaves at 11:05 PM.
Yes, there are 2 direct flights a day from Chicago, IL to Jefferson City, MO with United. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Chicago, IL to Jefferson City, MO, you can count on United for the best way to get you to Jefferson City, MO. You can also check all possible airlines who offer a service between Chicago, IL and Jefferson City, MO and compare the amenities they offer before buying a plane ticket.
Flights from Chicago, IL to Jefferson City, MO generally leave from O'Hare International Airport and arrive in Columbia Regional Airport.O'Hare International Airport is 1 miles (3 km) away from Chicago, IL city centre and Columbia Regional Airport is 10 miles (17 km) from Jefferson City, MO city centre.
The cheapest month for a flight from Chicago, IL to Jefferson City, MO is October.
It's helpful to compare your options as there are 3 ways to travel between Chicago, IL and Jefferson City, MO including taking a train, bus, and flight.
Since neither Chicago, IL nor Jefferson City, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between Chicago, IL and Jefferson City, MO.
We recommend using the train as it is the most popular way to get from Chicago, IL to Jefferson City, MO among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jefferson City, MO, travelers should be cautious of common urban safety concerns such as petty theft and vehicle break-ins, especially in less populated areas or at night. Scams involving overcharging or fake ticket offers can occur, so it's advisable to purchase transportation tickets from official sources. Staying aware of surroundings and safeguarding personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular airports

Popular airports from Chicago, IL to Jefferson City, MO

Most Chicago, IL to Jefferson City, MO flights use the O'Hare International Airport to Columbia Regional Airport airport pair. Use this guide to compare Chicago, IL and Jefferson City, MO airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.

Departure airports in Chicago
Arrival airports in Jefferson City

Which Chicago, IL airport do flights to Jefferson City, MO leave from?

Flights from Chicago, IL to Jefferson City, MO depart from O'Hare International Airport. The airport is 2 miles (4 km) from Chicago, IL city centre at 10000 W O'Hare Ave, Chicago, IL 60666, USA.
O'Hare International Airport (ORD)10000 W O'Hare Ave, Chicago, IL 60666, USAWifiShoppingParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeCar Rental
City-centre transport

Getting to O'Hare International Airport from Chicago city centre

O'Hare International Airport is 3 km from Chicago city centre. Public transport options include:

SubwayBlue Line · 1h 7m · $6 · every ~23 min

O'Hare International Airport airport facilities and services

O'Hare International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.

Food and drink

Food options include: Restaurants are located in all terminals, offering a variety of cuisines including American and intertiol. Top options include Tortas Frontera and Publican Tavern.

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are located throughout all terminals.

Luggage and lost property

Lost and found is available at the station.

Parking, taxis and toilets

Available at O'Hare International Airport: Parking, Taxis, WC.

Bike and car services

Available at O'Hare International Airport: Car Rental.

Accessibility

Accessibility facilities are available at O'Hare International Airport: Elevators, ramps, toilets.

Shops, hotels and contact

Nearby hotels include Hotels such as Hilton Chicago O'Hare are located on airport grounds, with others like the Hyatt Regency nearby..

More about O'Hare International Airport

More options for your journey from Chicago, IL to Jefferson City, MO

Here are some other resources that might have the information you need

Return journeys for flights from Jefferson City, MO to Chicago, IL
Buses from Chicago, IL to Jefferson City, MO
Trains from Chicago, IL to Jefferson City, MO
More information on flights to Chicago, IL
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