The cheapest and fastest buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Cheapest price
$26
Average price
$37
Fastest journey
2 h 45 m
Average duration
3 h 8 m
Buses per day
3
Distance
204 km
The best way to find a cheap bus ticket from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA will cost around $37 if you buy it on the day, but the cheapest tickets can be found for only $26.
Of the 3 buses that leave Santa Fe Depot, San Diego, CA for Van Nuys, Metrolink Station, Los Angeles, CA on Fri, Feb 06, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 06 the direct buses cover the 204 km distance in an average of 3 h 8 m but if you time it right, some buses will get you there in just 2 h 45 m .
On Fri, Feb 06 the slowest buses will take 3 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, and flight for Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Omio recommends booking the train as it is the most popular option from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 1h 48m. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €153.
Distance: 126 miles (204 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€28 Average price Cheapest | €35 Average price | €333 Average price |
4h 52m Average total duration 4h 22m Onboard + 30m Additional time* | 4h 15m Average total duration 3h 45m Onboard + 30m Additional time* | 4h 48m Average total duration Fastest 1h 48m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA bus times
The table below shows live departures for Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA buses for today, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:45 PM Santa Fe Depot, San Diego, CA | 3h35 | 7:20 PM Van Nuys, Metrolink Station, Los Angeles, CA | 0 transfersDirect | |
![]() | 4:50 PM Santa Fe Depot, San Diego, CA | 2h30 | 7:20 PM Van Nuys, Metrolink Station, Los Angeles, CA | 0 transfersDirect | |
![]() | 9:35 PM Santa Fe Depot, San Diego, CA | 3h20 | 12:55 AM Van Nuys, Metrolink Station, Los Angeles, CA | 0 transfersDirect | |
![]() | 10:10 PM Santa Fe Depot, San Diego, CA | 2h45 | 12:55 AM Van Nuys, Metrolink Station, Los Angeles, CA | 0 transfersDirect | |
| Friday, February 6 | |||||
![]() | 3:35 AM Santa Fe Depot, San Diego, CA | 2h45 | 6:20 AM Van Nuys, Metrolink Station, Los Angeles, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of to find the best option for your trip from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA.
Journey information
Overview: Bus from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA run on average 24 times per day, taking around 4h 22m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 19 buses per day. The earliest bus runs at 03:35, the last at 22:10. The fastest bus covers the 126 miles (204 km) distance in 2h 30m.
Distance 126 miles (204 km) |
Average bus duration 4h 22m |
Cheapest ticket price $24 (€19) |
Buses per day 24 |
Direct buses 19 |
Fastest bus 2h 30m |
First bus 03:35 |
Last bus 22:10 |
Bus providers: FlixBus from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CAYou can travel by bus between Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA with FlixBus for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Find answers to the most common questions about traveling from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Van Nuys, Metrolink Station, Los Angeles, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
Most popular bus connections from Santa Fe Depot, San Diego, CA
More options for your journey from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
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