The cheapest and fastest buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Cheapest price
$38
Average price
$61
Fastest journey
2 h 45 m
Average duration
2 h 59 m
Buses per day
24
Distance
204 km
The best way to find a cheap bus ticket from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA will cost around $61 if you buy it on the day, but the cheapest tickets can be found for only $38.
Of the 24 buses that leave Santa Fe Depot, San Diego, CA for Van Nuys, Metrolink Station, Los Angeles, CA on Sun, Jun 21, 21 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 204 km distance in an average of 2 h 59 m but if you time it right, some buses will get you there in just 2 h 45 m .
On Sun, Jun 21 the slowest buses will take 3 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus9:50 AM4h10La Jolla, UCSD Health La Jolla Station, CA2:00 PMSan Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop)$381One-way0 transfers
FlixBus9:25 AM4h35San Diego, Congress Street (Old Town Park), CA2:00 PMSan Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop)$381One-way0 transfers
FlixBus12:40 PM4h15San Diego, San Ysidro Transit Center4:55 PMLos Angeles, Patsaouras Transit Plaza (Union Station), CA$401One-way0 transfers
· 5:40 AM7h35San Diego, Congress Street (Old Town Park), CA1:15 PMLos Angeles, North Hollywood (W Magnolia Blvd / Klump Ave), CA$441One-way1 transfer
FlixBus · FlixBus+
8:55 AM7h55La Jolla, UCSD Health La Jolla Station, CA4:50 PMLos Angeles, North Hollywood (W Magnolia Blvd / Klump Ave), CA$451One-way2 transfers
07:51 PM2h45San Diego, CA10:36 PMLos Angeles, CA$831One-way0 transfers
06:30 AM3h00San Diego, CA9:30 AMLos Angeles, CA$561One-way0 transfers
011:30 AM3h00San Diego, CA2:30 PMLos Angeles, CA$561One-way0 transfers
FlixBus7:45 AM3h05San Diego, San Ysidro Transit Center10:50 AMDowney, Stonewood Center (251 Stonewood St), CA$691One-way0 transfers
05:51 PM3h05San Diego, CA8:56 PMLos Angeles, CA$831One-way0 transfers
Travel Information
Compare train, bus, and flight for Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Omio recommends booking the train as it is the most popular option from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $23. For those with little time consider booking a train which can get you there in 3h 45m. The ticket price range depends on the travel mode: a bus costs an average of $23, and a flight costs an average of $294.
Distance: 126 miles (204 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$28 Average price Cheapest | $43 Average price | $448 Average price | $36 Average price (fuel + tolls) |
4h 34m Average total duration 4h 4m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 3h 45m Onboard + 30m Additional time* | 7h 40m Average total duration 4h 40m Onboard + 3h 0m Additional time* | 2h 50m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA:
A bus is $15 (€12) less than a train for this route with tickets for a train from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA costing on average $43 (€35).
A bus is $420 (€343) less than a flight for this route with tickets for a flight from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA costing on average $448 (€367).
Other travel options to Van Nuys, Metrolink Station, Los Angeles, CA take longer:
Bus takes on average 4h 4m.
Flight takes on average 4h 40m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:35AM | Arrival Time 05:20AM | Duration 2h45 | Departure days Sat | Cheapest price $27 |
Operator Greyhound | Departure Time 04:55AM | Arrival Time 09:15AM | Duration 4h20 | Departure days Sun | Cheapest price $49 |
Operator Greyhound | Departure Time 05:40AM | Arrival Time 09:15AM | Duration 3h35 | Departure days Tue, Wed, Sat, Sun | Cheapest price $24 |
Operator Tufesa Internacional | Departure Time 06:30AM | Arrival Time 09:45AM | Duration 3h15 | Departure days Tue, Wed, Sat | Cheapest price $49 |
Operator Infobus | Departure Time 06:30AM | Arrival Time 09:30AM | Duration 3h00 | Departure days Sun | Cheapest price $56 |
Operator FlixBus | Departure Time 06:55AM | Arrival Time 11:35AM | Duration 4h40 | Departure days Sun | Cheapest price $57 |
Operator FlixBus | Departure Time 07:35AM | Arrival Time 11:35AM | Duration 4h00 | Departure days Tue, Wed, Sat | Cheapest price $33 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 10:50AM | Duration 3h05 | Departure days Sun | Cheapest price $69 |
Operator Infobus | Departure Time 07:51AM | Arrival Time 10:56AM | Duration 3h05 | Departure days Sun | Cheapest price $83 |
Operator Futura Net | Departure Time 07:51AM | Arrival Time 10:36AM | Duration 2h45 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator FlixBus | Departure Time 07:55AM | Arrival Time 11:35AM | Duration 3h40 | Departure days Tue, Wed, Sat | Cheapest price $33 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 10:50AM | Duration 2h20 | Departure days Wed, Sat | Cheapest price $35 |
Operator FlixBus | Departure Time 08:40AM | Arrival Time 12:45PM | Duration 4h05 | Departure days Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 08:55AM | Arrival Time 11:25AM | Duration 2h30 | Departure days Wed, Sat, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 02:00PM | Duration 4h35 | Departure days Tue, Wed, Sat, Sun | Cheapest price $26 |
Operator FlixBus | Departure Time 09:50AM | Arrival Time 02:00PM | Duration 4h10 | Departure days Tue, Wed, Sat, Sun | Cheapest price $26 |
Operator Futura Net | Departure Time 09:51AM | Arrival Time 12:36PM | Duration 2h45 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator Infobus | Departure Time 09:51AM | Arrival Time 12:56PM | Duration 3h05 | Departure days Sun | Cheapest price $83 |
Operator Tufesa Internacional | Departure Time 10:45AM | Arrival Time 02:45PM | Duration 4h00 | Departure days Tue, Wed, Sat | Cheapest price $49 |
Operator Infobus | Departure Time 10:45AM | Arrival Time 01:55PM | Duration 3h10 | Departure days Sun | Cheapest price $56 |
Operator Tufesa Internacional | Departure Time 11:30AM | Arrival Time 02:30PM | Duration 3h00 | Departure days Tue, Wed, Sat | Cheapest price $49 |
Operator Infobus | Departure Time 11:30AM | Arrival Time 02:30PM | Duration 3h00 | Departure days Sun | Cheapest price $56 |
Operator Infobus | Departure Time 11:51AM | Arrival Time 02:56PM | Duration 3h05 | Departure days Sun | Cheapest price $83 |
Operator Futura Net | Departure Time 11:51AM | Arrival Time 02:56PM | Duration 3h05 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 03:30PM | Duration 3h35 | Departure days Tue, Sat | Cheapest price $24 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 03:30PM | Duration 3h15 | Departure days Tue, Sat | Cheapest price $24 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 03:30PM | Duration 2h50 | Departure days Tue, Sat, Sun | Cheapest price $24 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 04:55PM | Duration 3h45 | Departure days Tue, Wed, Sat | Cheapest price $21 |
Operator FlixBus | Departure Time 01:35PM | Arrival Time 04:55PM | Duration 3h20 | Departure days Tue, Wed, Sat | Cheapest price $21 |
Operator Infobus | Departure Time 01:51PM | Arrival Time 04:56PM | Duration 3h05 | Departure days Sun | Cheapest price $83 |
Operator Futura Net | Departure Time 01:51PM | Arrival Time 04:36PM | Duration 2h45 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator Futura Net | Departure Time 03:51PM | Arrival Time 06:36PM | Duration 2h45 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator Infobus | Departure Time 03:51PM | Arrival Time 06:56PM | Duration 3h05 | Departure days Sun | Cheapest price $83 |
Operator FlixBus | Departure Time 03:55PM | Arrival Time 07:10PM | Duration 3h15 | Departure days Sat | Cheapest price $50 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 07:35PM | Duration 3h20 | Departure days Sat | Cheapest price $50 |
Operator FlixBus | Departure Time 04:50PM | Arrival Time 09:00PM | Duration 4h10 | Departure days Mon, Thu, Fri | Cheapest price $24 |
Operator Infobus | Departure Time 05:51PM | Arrival Time 08:56PM | Duration 3h05 | Departure days Sun | Cheapest price $83 |
Operator Futura Net | Departure Time 05:51PM | Arrival Time 08:56PM | Duration 3h05 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator Greyhound | Departure Time 07:10PM | Arrival Time 10:30PM | Duration 3h20 | Departure days Sun | Cheapest price $46 |
Operator Infobus | Departure Time 07:51PM | Arrival Time 10:36PM | Duration 2h45 | Departure days Sun | Cheapest price $83 |
Operator Futura Net | Departure Time 07:51PM | Arrival Time 10:56PM | Duration 3h05 | Departure days Tue, Wed, Sat | Cheapest price $76 |
Operator Greyhound | Departure Time 07:55PM | Arrival Time 11:40PM | Duration 3h45 | Departure days Tue, Wed, Sat, Sun | Cheapest price $20 |
Operator Tufesa Internacional | Departure Time 08:20PM | Arrival Time 12:20AM | Duration 4h00 | Departure days Tue, Wed, Sat | Cheapest price $49 |
Operator Infobus | Departure Time 08:20PM | Arrival Time 12:20AM | Duration 4h00 | Departure days Sun | Cheapest price $56 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 11:55PM | Duration 3h20 | Departure days Mon | Cheapest price $26 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 12:55AM | Duration 3h20 | Departure days Thu, Fri | Cheapest price $36 |
Live departures
Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA bus times
The table below shows live departures for Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
0 | 5:51 PM San Diego, CA | 2h45 | 8:36 PM Los Angeles, CA | 0 transfersDirect | |
0 | 7:51 PM San Diego, CA | 2h45 | 10:36 PM Los Angeles, CA | 0 transfersDirect | |
![]() | 7:55 PM San Diego, Congress Street (Old Town Park), CA | 3h45 | 11:40 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop) | 0 transfersDirect | |
![]() | 7:55 PM San Diego, Congress Street (Old Town Park), CA | 2h35 | 10:30 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 0 transfersDirect | |
0 | 8:20 PM San Diego, CA | 4h00 | 12:20 AM Los Angeles, CA | 0 transfersDirect | |
![]() | 4:55 AM San Diego, San Ysidro Transit Center | 4h20 | 9:15 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 0 transfersDirect | |
· | 5:40 AM San Diego, Congress Street (Old Town Park), CA | 7h35 | 1:15 PM Los Angeles, North Hollywood (W Magnolia Blvd / Klump Ave), CA | 1 transfer | |
0 | 6:30 AM San Diego, CA | 3h00 | 9:30 AM Los Angeles, CA | 0 transfersDirect | |
FlixBus | 6:55 AM San Diego, San Ysidro Transit Center | 4h40 | 11:35 AM Los Angeles, Cesar E Chavez / Vignes, CA | 0 transfersDirect | |
FlixBus | 7:45 AM San Diego, San Ysidro Transit Center | 3h05 | 10:50 AM Downey, Stonewood Center (251 Stonewood St), CA | 0 transfersDirect | |
FlixBus | 7:45 AM San Diego, San Ysidro Transit Center | 3h40 | 11:25 AM Los Angeles, Cesar E Chavez / Vignes, CA | 0 transfersDirect | |
0 | 7:51 AM San Diego, CA | 3h05 | 10:56 AM Los Angeles, CA | 0 transfersDirect | |
FlixBus | 8:40 AM San Diego, San Ysidro Transit Center | 4h05 | 12:45 PM Los Angeles, Cesar E Chavez / Vignes, CA | 0 transfersDirect | |
FlixBus · FlixBus+![]() | 8:55 AM La Jolla, UCSD Health La Jolla Station, CA | 7h55 | 4:50 PM Los Angeles, North Hollywood (W Magnolia Blvd / Klump Ave), CA | 2 transfers | |
FlixBus | 9:25 AM San Diego, Congress Street (Old Town Park), CA | 4h35 | 2:00 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop) | 0 transfersDirect | |
FlixBus | 9:50 AM La Jolla, UCSD Health La Jolla Station, CA | 4h10 | 2:00 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop) | 0 transfersDirect | |
0 | 9:51 AM San Diego, CA | 3h05 | 12:56 PM Los Angeles, CA | 0 transfersDirect | |
0 | 10:45 AM San Diego, CA | 3h10 | 1:55 PM Los Angeles, CA | 0 transfersDirect | |
0 | 11:30 AM San Diego, CA | 3h00 | 2:30 PM Los Angeles, CA | 0 transfersDirect | |
0 | 11:51 AM San Diego, CA | 3h05 | 2:56 PM Los Angeles, CA | 0 transfersDirect | |
FlixBus | 12:40 PM San Diego, San Ysidro Transit Center | 4h15 | 4:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 0 transfersDirect | |
0 | 1:51 PM San Diego, CA | 3h05 | 4:56 PM Los Angeles, CA | 0 transfersDirect | |
0 | 3:51 PM San Diego, CA | 3h05 | 6:56 PM Los Angeles, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 21
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Jun 27
Journey information
Overview: Bus from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA run on average 20 times per day, taking around 4h 4m. Cheap bus tickets for this journey start at $23 (€18) if you book in advance.
There are 17 buses per day. The earliest bus runs at 02:00, the last at 21:35. The fastest bus covers the 126 miles (204 km) distance in 2h 45m.
Distance 126 miles (204 km) |
Average bus duration 4h 4m |
Cheapest ticket price $23 (€18) |
Buses per day 20 |
Direct buses 17 |
Fastest bus 2h 45m |
First bus 2:00 AM |
Last bus 9:35 PM |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Sun |
FAQs: Bus from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Find answers to the most common questions about traveling from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Van Nuys, Metrolink Station, Los Angeles, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
Most Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA buses use the San Diego, Congress Street (Old Town Park) to Los Angeles, Patsaouras Transit Plaza (Union Station) station pair, with some services arriving at Los Angeles, Cesar E Chavez / Vignes. Use this guide to compare Santa Fe Depot, San Diego, CA and Van Nuys, Metrolink Station, Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
Getting to San Diego from San Diego city centre
Getting to Los Angeles, Patsaouras Transit Plaza (Union Station) from Los Angeles city centre
Getting to Los Angeles, Cesar E Chavez / Vignes from Los Angeles city centre
Getting to Los Angles, S Hope St. USC Parking from Los Angeles city centre
Most popular bus connections from Santa Fe Depot, San Diego, CA
More options for your journey from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA
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